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738
Expression of homologous RND efflux pump genes is dependent upon AcrB
, 2014
"... expression: implications for efflux and virulence inhibitor design ..."
Spread of invasive Spanish Staphylococcus aureus spa-type t067 associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(49)-Ia and the efflux pump genes msrA/msrB
- J Antimicrob Chemother
, 2009
"... associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(40)-Ia and the efflux pump genes msrA/msrB ..."
Abstract
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Cited by 5 (0 self)
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associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(40)-Ia and the efflux pump genes msrA/msrB
Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes. Antimicrob. Agents Chemother
, 2001
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Ethidium bromide MIC screening for enhanced efflux pump gene expression or efflux activity in Staphylococcus aureus. Antimicrob Agents Chemother 2010;54
"... Multidrug resistance efflux pumps contribute to antimicrobial and biocide resistance in Staphylococcus aureus. The detection of strains capable of efflux is time-consuming and labor-intensive using currently available techniques. A simple and inexpensive method to identify such strains is needed. Et ..."
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Cited by 1 (0 self)
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-PCR identified the increased expression of one or more MDR efflux pump genes in 151/309 clinical strains (49%). Ethidium bromide MIC testing was insensitive (48%) but specific (92%) in identifying strains with gene overexpression, but it was highly sensitive (95%) and specific (99%) in identifying strains
Method for Regulated Expression of Single-Copy Efflux Pump Genes in a Surrogate Pseudomonas aeruginosa Strain: Identification of the
, 2006
"... Construction and integration of recombinant mini-Tn7 expression vectors into the chromosome of a surrogate, efflux-sensitized, and biosafe Pseudomonas aeruginosa host was validated as a generally applicable method for studies of uncharacterized bacterial efflux pumps. Using this method, the Burkhold ..."
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Construction and integration of recombinant mini-Tn7 expression vectors into the chromosome of a surrogate, efflux-sensitized, and biosafe Pseudomonas aeruginosa host was validated as a generally applicable method for studies of uncharacterized bacterial efflux pumps. Using this method
Dueling Regulatory Properties of a Transcriptional Activator (MtrA) and Repressor (MtrR) That Control Efflux Pump Gene Expression in
"... ABSTRACT MtrA is a member of the AraC family of transcriptional regulators and has been shown to play an important role in enhancing transcription of themtrCDE operon, which encodes a tripartite multidrug efflux pump, when gonococci are exposed to a sublethal level of antimicrobials. Heretofore, the ..."
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ABSTRACT MtrA is a member of the AraC family of transcriptional regulators and has been shown to play an important role in enhancing transcription of themtrCDE operon, which encodes a tripartite multidrug efflux pump, when gonococci are exposed to a sublethal level of antimicrobials. Heretofore
Expression of Multidrug Efflux Pump Genes acrAB-tolC, mdfA, and norE in Escherichia coli Clinical Isolates as a Function of
, 2010
"... In a single quantitative study, we measured acrA, acrB, tolC, mdfA, and norE expression in Escherichia coli clinical isolates by using real-time PCR. acrA and acrB overexpression strongly correlated with fluoroquinolone and multidrug resistance; tolC, mdfA, and norE expression did not. The order of ..."
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of abundance of efflux pump transcripts in all fluoroquinolone-susceptible isolates was tolC (highest), then acrA and acrB, and then mdfA and norE. Our findings suggest acrAB overexpression is an indicator of multidrug resistance. Multidrug resistance (MDR) is an increasing public health concern worldwide (7
resistance; Fluorescence real-time quantitative PCR; Knockout
"... CONCLUSION: The efflux pump gene hefA plays an important role in multidrug resistance of H pylori. ..."
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CONCLUSION: The efflux pump gene hefA plays an important role in multidrug resistance of H pylori.
from the National Institutes of Health (R01
, 2015
"... Sodium-pump gene-expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney ..."
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Sodium-pump gene-expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney
Results 1 - 10
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738