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Acinetobacter calcoaceticus–Acinetobacter

by Tse Hsien Koh, Li-hwei Sng, Grace Chee, Yeng Wang, Li-yang Hsu, Yi Zhao
"... Carbapenemase and efflux pump genes in ..."
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Carbapenemase and efflux pump genes in

Expression of homologous RND efflux pump genes is dependent upon AcrB

by Jessica M. A. Blair, Helen E. Smith, Vito Ricci, Amelia J. Lawler, Louisa J. Thompson, Laura J. V. Piddock , 2014
"... expression: implications for efflux and virulence inhibitor design ..."
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expression: implications for efflux and virulence inhibitor design

Spread of invasive Spanish Staphylococcus aureus spa-type t067 associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(49)-Ia and the efflux pump genes msrA/msrB

by Ana Vindel, Carmen Marcos, Oscar Cuevas, Pilar Trincado, Hajo Grundmann, Jose ́ Campos - J Antimicrob Chemother , 2009
"... associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(40)-Ia and the efflux pump genes msrA/msrB ..."
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associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(40)-Ia and the efflux pump genes msrA/msrB

Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes. Antimicrob. Agents Chemother

by Mark C. Sulavik, Chad Houseweart, Christina Cramer, Nilofer Jiwani, Nicholas Murgolo, Jonathan Greene, Karen Joy Shaw, George H. Miller, George Shimer, Mark C. Sulavik, Chad Houseweart, Christina Cramer, Nilofer Jiwani, Nicholas Murgolo, Jonathan Greene, Beth Didomenico, Karen Joy Shaw, George H. Miller, Roberta Hare , 2001
"... Updated information and services can be found at: ..."
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Updated information and services can be found at:

Ethidium bromide MIC screening for enhanced efflux pump gene expression or efflux activity in Staphylococcus aureus. Antimicrob Agents Chemother 2010;54

by Diixa Patel, Christos Kosmidis, Susan M. Seo, Glenn W. Kaatz
"... Multidrug resistance efflux pumps contribute to antimicrobial and biocide resistance in Staphylococcus aureus. The detection of strains capable of efflux is time-consuming and labor-intensive using currently available techniques. A simple and inexpensive method to identify such strains is needed. Et ..."
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-PCR identified the increased expression of one or more MDR efflux pump genes in 151/309 clinical strains (49%). Ethidium bromide MIC testing was insensitive (48%) but specific (92%) in identifying strains with gene overexpression, but it was highly sensitive (95%) and specific (99%) in identifying strains

Method for Regulated Expression of Single-Copy Efflux Pump Genes in a Surrogate Pseudomonas aeruginosa Strain: Identification of the

by Bpeef-oprc Chloramphenicol, Trimethoprim Efflux Pump, Ayush Kumar, Kim-lee Chua, Herbert P. Schweizer , 2006
"... Construction and integration of recombinant mini-Tn7 expression vectors into the chromosome of a surrogate, efflux-sensitized, and biosafe Pseudomonas aeruginosa host was validated as a generally applicable method for studies of uncharacterized bacterial efflux pumps. Using this method, the Burkhold ..."
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Construction and integration of recombinant mini-Tn7 expression vectors into the chromosome of a surrogate, efflux-sensitized, and biosafe Pseudomonas aeruginosa host was validated as a generally applicable method for studies of uncharacterized bacterial efflux pumps. Using this method

Dueling Regulatory Properties of a Transcriptional Activator (MtrA) and Repressor (MtrR) That Control Efflux Pump Gene Expression in

by Neisseria Gonorrhoeae, Yaramah M. Zalucki, A Vijaya Dhulipala, William M. Shafera
"... ABSTRACT MtrA is a member of the AraC family of transcriptional regulators and has been shown to play an important role in enhancing transcription of themtrCDE operon, which encodes a tripartite multidrug efflux pump, when gonococci are exposed to a sublethal level of antimicrobials. Heretofore, the ..."
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ABSTRACT MtrA is a member of the AraC family of transcriptional regulators and has been shown to play an important role in enhancing transcription of themtrCDE operon, which encodes a tripartite multidrug efflux pump, when gonococci are exposed to a sublethal level of antimicrobials. Heretofore

Expression of Multidrug Efflux Pump Genes acrAB-tolC, mdfA, and norE in Escherichia coli Clinical Isolates as a Function of

by Multidrug Resistance, Michelle C. Swick, Sonia K. Morgan-linnell, Kimberly M. Carlson, Lynn Zechiedrich , 2010
"... In a single quantitative study, we measured acrA, acrB, tolC, mdfA, and norE expression in Escherichia coli clinical isolates by using real-time PCR. acrA and acrB overexpression strongly correlated with fluoroquinolone and multidrug resistance; tolC, mdfA, and norE expression did not. The order of ..."
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of abundance of efflux pump transcripts in all fluoroquinolone-susceptible isolates was tolC (highest), then acrA and acrB, and then mdfA and norE. Our findings suggest acrAB overexpression is an indicator of multidrug resistance. Multidrug resistance (MDR) is an increasing public health concern worldwide (7

resistance; Fluorescence real-time quantitative PCR; Knockout

by unknown authors
"... CONCLUSION: The efflux pump gene hefA plays an important role in multidrug resistance of H pylori. ..."
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CONCLUSION: The efflux pump gene hefA plays an important role in multidrug resistance of H pylori.

from the National Institutes of Health (R01

by Pnina Scherzer, Anca Gal-moscovici, David Sheikh-hamad, Mordecai M. Popovtzer, Pnina Scherzer , 2015
"... Sodium-pump gene-expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney ..."
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Sodium-pump gene-expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney
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