This article cites 30 articles, 15 of which can be accessed free

Recombinant bacterial systems exhibit limited capaci-ties for heterologous protein production. As seen with this and other systems, cloned-gene protein production reaches an upper limit despite further increases in gene dosage. A series of closely related plasmids which con-tain mutations affecting

lantic cod (Gadus morhua) were held either at seasonal ambient temperatures (0.3 to 11°C) or at a relatively constant control temperature (8–11°C) to investigate aspects of protein synthesis during a period of compensatory growth. Protein synthesis rate, total RNA, and RNA-specific protein

Cilk (pronounced “silk”) is a C-based runtime system for multithreaded parallel programming. In this paper, we document the efficiency of the Cilk work-stealing scheduler, both empirically and analytically. We show that on real and synthetic applications, the “work” and “critical path ” of a Cilk

Persistent microvascular hyperpermeability to plasma proteins even after the cessation of injury is a characteristic but poorly understood feature of normal wound healing. It results in extravasation of fibrinogen that clots to form fibrin, which serves as a provisional matrix and promotes

to 3 decay pathways, respectively. We also demonstrate the use of 4-fold multiplexing to enable relative protein measurements simultaneously with determination of absolute levels of a target protein using synthetic isobaric peptide standards. We find that inactivation of Upf1p and Xrn1p causes common

this paper is the interactions occurring within specific complexes. These were obtained from the MIPS complexes catalog (Fellenberg et al. 2000), which represents a carefully annotated, comprehensive data set of protein complexes culled from the scientific literature. In addition, we looked

-folding capacity in the ER according to need. The ER responds to the burden of unfolded proteins in its lumen (ER stress) by activating intracellular signal transduction pathways, collectively termed the unfolded protein response (UPR). Together, at least three mechanistically distinct branches of the UPR regulate

systems. In the case of the Web, understanding the nature of reference locality will help improve the design of middleware, such as caching, prefetching, and document dissemination systems. For example, good measurements of reference locality would allow us to generate synthetic reference streams

Articles in PresS. Am J Physiol Regul Integr Comp Physiol (August 26, 2004). doi:10.1152/ajpregu.00109.2004 Enhanced protein synthetic capacity in Atlantic cod (Gadus morhua) is associated with temperature induced compensatory growth.