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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

by Wolfgang Kabsch, Christian Sander , 1983
"... For a successful analysis of the relation between amino acid sequence and protein structure, an unambiguous and physically meaningful definition of secondary structure is essential. We have developed a set of simple and physically motivated criteria for secondary structure, programmed as a pattern-r ..."
Abstract - Cited by 2096 (5 self) - Add to MetaCart
for an overall view and strip tables for the details of each of 10,925 residues. The dictionary is also available in computer-readable form for protein structure prediction work.

Protein Secondary Structure Prediction . . .

by David T. Jones - JO MOL B/O/. (1999) 292, 195-202 .GG , 1999
"... ..."
Abstract - Cited by 945 (19 self) - Add to MetaCart
Abstract not found

Prediction of Protein Secondary Structure at Better than 70% Accuracy

by Burkhard Rost, Chris Sander , 1993
"... ..."
Abstract - Cited by 759 (40 self) - Add to MetaCart
Abstract not found

Identification of Prokaryotic and Eukaryotic Signal Peptides and Prediction of Their Cleavage Sites

by Henrik Nielsen, Jacob Engelbrecht, Søren Brunak, Gunnar von Heijne , 1997
"... We have developed a new method for identification of signal peptides and their cleavage sites based on neural networks trained on separate sets of prokaryotic and eukaryotic sequences. The method performs significantly better than previous prediction schemes, and can easily be applied on genome-wide ..."
Abstract - Cited by 787 (17 self) - Add to MetaCart
the protein is translocated through the membrane. The common structure of signal peptides from variou...

The SWISS-MODEL Workspace: A web-based environment for protein structure homology modelling

by Konstantin Arnold, Lorenza Bordoli, Torsten Schwede, et al. - BIOINFORMATICS , 2005
"... Motivation: Homology models of proteins are of great interest for planning and analyzing biological experiments when no experimental three-dimensional structures are available. Building homology models requires specialized programs and up-to-date sequence and structural databases. Integrating all re ..."
Abstract - Cited by 575 (5 self) - Add to MetaCart
dedicated to protein structure homology modelling. It assists and guides the user in building protein homology models at different levels of complexity. A personal working environment is provided for each user where several modelling projects can be carried out in parallel. Protein sequence and structure

Cilk: An Efficient Multithreaded Runtime System

by Robert D. Blumofe, Christopher F. Joerg, Bradley C. Kuszmaul, Charles E. Leiserson, Keith H. Randall, Yuli Zhou , 1995
"... Cilk (pronounced “silk”) is a C-based runtime system for multithreaded parallel programming. In this paper, we document the efficiency of the Cilk work-stealing scheduler, both empirically and analytically. We show that on real and synthetic applications, the “work” and “critical path ” of a Cilk co ..."
Abstract - Cited by 763 (33 self) - Add to MetaCart
computation can be used to accurately model performance. Consequently, a Cilk programmer can focus on reducing the work and critical path of his computation, insulated from load balancing and other rtmtime scheduling issues. We also prove that for the class of “fully strict ” (well-structured) programs

Toward a model of text comprehension and production

by Walter Kintsch, Teun A. Van Dijk - Psychological Review , 1978
"... The semantic structure of texts can be described both at the local microlevel and at a more global macrolevel. A model for text comprehension based on this notion accounts for the formation of a coherent semantic text base in terms of a cyclical process constrained by limitations of working memory. ..."
Abstract - Cited by 557 (12 self) - Add to MetaCart
The semantic structure of texts can be described both at the local microlevel and at a more global macrolevel. A model for text comprehension based on this notion accounts for the formation of a coherent semantic text base in terms of a cyclical process constrained by limitations of working memory

Protein structure prediction and structural genomics

by David Baker, Andrej Sali - Science , 2001
"... Genome sequencing projects are producing linear amino acid sequences, but full understanding of the biological role of these proteins will require knowledge of their structure and function. Although experimental structure determination methods are providing high-resolution structure information abou ..."
Abstract - Cited by 332 (14 self) - Add to MetaCart
about a subset of the proteins, computational structure prediction methods will provide valuable information for the large fraction of sequences whose structures will not be determined experimentally. The first class of protein structure prediction methods, including threading and comparative modeling

Protein homology detection by HMM-HMM comparison

by Johannes Söding - BIOINFORMATICS , 2005
"... Motivation: Protein homology detection and sequence alignment are at the basis of protein structure prediction, function prediction, and evolution. Results: We have generalized the alignment of protein se-quences with a profile hidden Markov model (HMM) to the case of pairwise alignment of profile H ..."
Abstract - Cited by 401 (8 self) - Add to MetaCart
Motivation: Protein homology detection and sequence alignment are at the basis of protein structure prediction, function prediction, and evolution. Results: We have generalized the alignment of protein se-quences with a profile hidden Markov model (HMM) to the case of pairwise alignment of profile

What memory is for

by Arthur M. Glenberg , 1997
"... Let’s start from scratch in thinking about what memory is for, and consequently, how it works. Suppose that memory and conceptualization work in the service of perception and action. In this case, conceptualization is the encoding of patterns of possible physical interaction with a three-dimensiona ..."
Abstract - Cited by 396 (5 self) - Add to MetaCart
Let’s start from scratch in thinking about what memory is for, and consequently, how it works. Suppose that memory and conceptualization work in the service of perception and action. In this case, conceptualization is the encoding of patterns of possible physical interaction with a three
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