Results 1 - 10 of 153,757

Functional discovery via a compendium of expression profiles.

by Timothy R Hughes , Matthew J Marton , Allan R Jones , Christopher J Roberts , Roland Stoughton , Christopher D Armour , Holly A Bennett , Ernest Coffey , Hongyue Dai , Ross-Macdonald , Yudong D He , Matthew J Kidd , Amy M King , Michael R Meyer , David Slade , Pek Y Lum , Sergey B Stepaniants , Daniel D Shoemaker , Julian Simon , Martin Bard - Cell, , 2000
"... provided that the cellular transcriptional response to frames encode proteins required for sterol metabodisruption of different steps in the same pathway is lism, cell wall function, mitochondrial respiration, or similar, and that there are sufficiently unique transcripprotein synthesis. We also sh ..."
Abstract - Cited by 547 (9 self) - Add to MetaCart
dyclonine. sion measurement. Using a comprehensive database of reference profiles, the pathway(s) perturbed by an Introduction uncharacterized mutation would be ascertained by simply asking which expression patterns in the database Systematic approaches for identifying the biological its profile most

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.

by Ash A Alizadeh , Michael B Eisen , R Eric Davis , Chi Ma , Izidore S Lossos , Andreas Rosenwald , Jennifer C Boldrick , Hajeer Sabet , Truc Tran , Xin Yu , John I Powell , Liming Yang , Gerald E Marti , Troy Moore , James Hudson Jr , Lisheng Lu , David B Lewis , Robert Tibshirani , Gavin Sherlock , Wing C Chan , Timothy C Greiner , Dennis D Weisenburger , James O Armitage , Roger Warnke , Ronald Levy , Wyndham Wilson , Michael R Grever , John C Byrd , David Botstein , Patrick O Brown , Louis M Staudt - Nature , 2000
"... ..."
Abstract - Cited by 642 (10 self) - Add to MetaCart
Abstract not found

gprof: a Call Graph Execution Profiler

by Susan L. Graham, Peter B. Kessler, Marshall K. McKusick , 1982
"... Large complex programs are composed of many small routines that implement abstractions for the routines that call them. To be useful, an execution profiler must attribute execution time in a way that is significant for the logical structure of a program as well as for its textual decomposition. This ..."
Abstract - Cited by 414 (0 self) - Add to MetaCart
Large complex programs are composed of many small routines that implement abstractions for the routines that call them. To be useful, an execution profiler must attribute execution time in a way that is significant for the logical structure of a program as well as for its textual decomposition

Benchmarking Optimization Software with Performance Profiles

by Elizabeth D. Dolan, Jorge J. Moré , 2001
"... We propose performance profiles --- distribution functions for a performance metric --- as a tool for benchmarking and comparing optimization software. We show that performance profiles combine the best features of other tools for performance evaluation. 1 Introduction The benchmarking of optimi ..."
Abstract - Cited by 386 (8 self) - Add to MetaCart
We propose performance profiles --- distribution functions for a performance metric --- as a tool for benchmarking and comparing optimization software. We show that performance profiles combine the best features of other tools for performance evaluation. 1 Introduction The benchmarking

NewsWeeder: Learning to Filter Netnews

by Ken Lang - in Proceedings of the 12th International Machine Learning Conference (ML95 , 1995
"... A significant problem in many information filtering systems is the dependence on the user for the creation and maintenance of a user profile, which describes the user's interests. NewsWeeder is a netnews-filtering system that addresses this problem by letting the user rate his or her interest l ..."
Abstract - Cited by 561 (0 self) - Add to MetaCart
A significant problem in many information filtering systems is the dependence on the user for the creation and maintenance of a user profile, which describes the user's interests. NewsWeeder is a netnews-filtering system that addresses this problem by letting the user rate his or her interest

Pfam protein families database

by Robert D. Finn, John Tate, Jaina Mistry, Penny C. Coggill, Stephen John Sammut, Hans-rudolf Hotz, Goran Ceric, Kristoffer Forslund, Sean R. Eddy, Erik L. L. Sonnhammer, Alex Bateman - Nucleic Acids Research, 2008, 36(Database issue): D281–D288
"... Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam (22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI GenP ..."
Abstract - Cited by 771 (13 self) - Add to MetaCart
Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam (22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI Gen

MATRIX FACTORIZATION TECHNIQUES FOR RECOMMENDER SYSTEMS

by Yehuda Koren, Robert Bell, Chris Volinsky - IEEE COMPUTER , 2009
"... As the Netflix Prize competition has demonstrated, matrix factorization models are superior to classic nearest-neighbor techniques for producing product recommendations, allowing the incorporation of additional information such as implicit feedback, temporal effects, and confidence levels. Modern co ..."
Abstract - Cited by 593 (4 self) - Add to MetaCart
, recommender systems are based on one of two strategies. The content filtering approach creates a profile for each user or product to characterize its nature. For example, a movie profile could include attributes regarding its genre, the participating actors, its box office popularity, and so forth. User

Denaturing gradient gel electrophoresis of PCR-amplified 16S rDNA. A new molecular approach to analyze the genetic diversity of mixed microbial communities

by M J Ferris, G Muyzer, D M Ward, M. J. Ferris, G. Muyzer, D. M. Ward
"... Denaturing gradient gel electrophoresis profiles of 16S rRNA-defined populations inhabiting a hot spring microbial mat community. ..."
Abstract - Cited by 479 (37 self) - Add to MetaCart
Denaturing gradient gel electrophoresis profiles of 16S rRNA-defined populations inhabiting a hot spring microbial mat community.

An intrusion-detection model

by Dorothy E. Denning - IEEE TRANSACTIONS ON SOFTWARE ENGINEERING , 1987
"... A model of a real-time intrusion-detection expert system capable of detecting break-ins, penetrations, and other forms of computer abuse is described. The model is based on the hypothesis that security violations can be detected by monitoring a system's audit records for abnormal patterns of sy ..."
Abstract - Cited by 639 (0 self) - Add to MetaCart
of system usage. The model includes profiles for representing the behavior of subjects with respect to objects in terms of metrics and statistical models, and rules for acquiring knowledge about this behavior from audit records and for detecting anomalous behavior. The model is independent of any particular

Social Information Filtering: Algorithms for Automating "Word of Mouth"

by Upendra Shardanand, Pattie Maes , 1995
"... This paper describes a technique for making personalized recommendations from any type of database to a user based on similarities between the interest profile of that user and those of other users. In particular, we discuss the implementation of a networked system called Ringo, which makes personal ..."
Abstract - Cited by 1159 (20 self) - Add to MetaCart
This paper describes a technique for making personalized recommendations from any type of database to a user based on similarities between the interest profile of that user and those of other users. In particular, we discuss the implementation of a networked system called Ringo, which makes
Results 1 - 10 of 153,757