Abstract not found

In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular functions, their large-scale structure is essentially unknown. Here we present the first systematic comparative mathematical analysis of the metabolic networks of 43 organisms representing all three domains of life. We show that, despite significant variances in their individual constituents and pathways, these metabolic networks display the same topologic scaling properties demonstrating striking similarities to the inherent organization of complex non-biological systems. This suggests that the metabolic organization is not only identical for all living organisms, but complies with the design principles of robust and error-tolerant networks, and may represent a common blueprint for the large-scale organization of interactions among all cellular constituents.

On behalf of:

Research on ontology is becoming increasingly widespread in the computer science community, and its importance is being recognized in a multiplicity of research fields and application areas, including knowledge engineering, database design and integration, information retrieval and extraction. We shall use the generic term information systems, in its broadest sense, to collectively refer to these application perspectives. We argue in this paper that so-called ontologies present their own methodological and architectural peculiarities: on the methodological side, their main peculiarity is the adoption of a highly interdisciplinary approach, while on the architectural side the most interesting aspect is the centrality of the role they can play in an information system, leading to the perspective of ontology-driven information systems.

A large portion of real-world data is stored in commercial relational database systems. In contrast, most statistical learning methods work only with "flat " data representations. Thus, to apply these methods, we are forced to convert our data into a flat form, thereby losing much of the relational structure present in our database. This paper builds on the recent work on probabilistic relational models (PRMs), and describes how to learn them from databases. PRMs allow the properties of an object to depend probabilistically both on other properties of that object and on properties of related objects. Although PRMs are significantly more expressive than standard models, such as Bayesian networks, we show how to extend well-known statistical methods for learning Bayesian networks to learn these models. We describe both parameter estimation and structure learning — the automatic induction of the dependency structure in a model. Moreover, we show how the learning procedure can exploit standard database retrieval techniques for efficient learning from large datasets. We present experimental results on both real and synthetic relational databases. 1

This paper empirically investigates the effects of liberalized trade on plant productivity in the case of Chile. Chile presents an interesting setting to study this relationship since it underwent a massive trade liberalization that significantly exposed its plants to competition from abroad during the late 1970s and early 1980s. Methodologically, I approach this question in two steps. In the first step, I estimate a production function to obtain a measure of plant productivity. I estimate the production function semiparametrically to correct for the presence of selection and simultaneity biases in the estimates of the input coefficients required to construct a productivity measure. I explicitly incorporate plant exit in the estimation to correct for the selection problem induced by liquidated plants. These methodological aspects are important in obtaining a reliable plant-level productivity measure based on consistent estimates of the input coefficients. In the second step, I identify the impact of trade on plants’ productivity in a regression framework allowing variation in productivity over time and across tradedand nontraded-goods sectors. Using plant-level panel data on Chilean manufacturers, I find evidence of within plant productivity improvements that can be attributed to a liberalized trade for the plants in the import-competing sector. In many cases, aggregate productivity improvements stem from the reshuffling of resources and output from less to more efficient producers.

Eric Brill introduced transformation-based learning and showed that it can do part-ofspeech tagging with fairly high accuracy. The same method can be applied at a higher level of textual interpretation for locating chunks in the tagged text, including non-recursive "baseNP" chunks. For this purpose, it is convenient to view chunking as a tagging problem by encoding the chunk structure in new tags attached to each word. In automatic tests using Treebank-derived data, this technique achieved recall and precision rates of roughly 92% for baseNP chunks and 88% for somewhat more complex chunks that partition the sentence. Some interesting adaptations to the transformation-based learning approach are also suggested by this application.

Abstract not found

Most current approaches to concurrency control in database systems rely on locking of data objects as a control mechanism. In this paper, two families of nonlocking concurrency controls are presented. The methods used are “optimistic ” in the sense that they rely mainly on transaction backup as a control mechanism, “hoping ” that conflicts between transactions will not occur. Applications for which these methods should be more efficient than locking are discussed.

this document length correction factor is #global": it is added at the end, after the weights for the individual terms have been summed, and is independentofwhich terms match.