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215
Postexposure Treatment of Marburg Virus Infection
"... Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered ..."
Abstract
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Cited by 5 (1 self)
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against the filoviruses have not kept pace. Some degree of success has been achieved by using strategies that mitigate the coagulation abnormalities characterizing filoviral infection (2,3). Also, new postexposure treatment approaches, based on small interfering RNA (4) and antisense oligomers (5,6), have
Use of mouse anti-rabies monoclonal antibodies in postexposure treatment of rabies
- J. Clin. Investig
, 1989
"... Immunization of mice and hamsters with a cocktail of mouse MAbs specific for rabies virus nucleocapsid protein and glyco-protein protected animals not only when challenged with a lethal dose of rabies virus after immunization, but also in post-exposure situations. Hamsters treated with the MAb cockt ..."
Abstract
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Cited by 5 (4 self)
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cocktail 3 h after virus inoculation were completely protected from lethal rabies virus infection, and 80 % of the animals survived when the MAb cocktail was given 36 h after virus challenge. The potential usefulness of this MAb cocktail for the postex-posure treatment of human rabies is discussed.
Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs
- J. Virol
, 2002
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Postexposure treatment of rabies infection: can it be done without immunoglobulin? Clin. Infect. Dis
, 2002
"... The last remaining international manufacturer of equine rabies immunoglobulin (ERIG) discontinued production in 2001. However, ERIG remains an essential biological that has no substitute other than human rabies immunoglobulin (HRIG), which is in short supply and virtually unaffordable in developing ..."
Abstract
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Cited by 2 (0 self)
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countries. Physicians in regions where canine rabies is endemic and neither ERIG nor HRIG is available are providing less-than-optimal treatment to patients exposed to rabies. If no immunoglobulin is available, they have only 1 therapy option: use of a vaccine schedule that produces the highest and
The Primary Hamster Kidney Cell Rabies Vaccine: Adaptation of Viral Strain, Production of Vaccine, and Pre- and Postexposure Treatment
"... The hamster kidney cell rabies vaccine was investigated as a substitute for classical ner-vous tissue rabies vaccine. The Beijing strain of fixed rabies virus was adapted to primary hamster kidney cells (PHKCs), and four types of rabies vaccine (plain, adju-vant, concentrated, and concentrated adjuv ..."
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adjuvant vaccines) were developed for human use. The potencies of the vaccines met the requirements of the World Health Organiza-tion, and these vaccines elicited rather satisfactory antibody responses in volunteers. The postexposure use of vaccine was evaluated in 301 individuals, 97 of whom had been
Postexposure Treatment with the Live-Attenuated Rabies Virus (RV) Vaccine TriGAS Triggers the Clearance of Wild-Type RV from the Central Nervous System (CNS) through the Rapid Induction of Genes Relevant to Adaptive Immunity in CNS Tissues
"... Postexposure treatment (PET) of wild-type rabies virus (RV)-infected mice with a live-attenuated triple-glycoprotein RV variant (TriGAS) promotes survival but does not prevent the pathogenic RV from invading and replicating in the brain. Successful PET is associated with the induction of a robust vi ..."
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Postexposure treatment (PET) of wild-type rabies virus (RV)-infected mice with a live-attenuated triple-glycoprotein RV variant (TriGAS) promotes survival but does not prevent the pathogenic RV from invading and replicating in the brain. Successful PET is associated with the induction of a robust
Treatment and in the Post-Exposure Period
"... Abstract: The prevalence of trimethoprim (TMP) and sulfamethoxazole (SMX) resistance in commensal E. coli from pigs was tested in this study. E. coli was derived from three groups of piglets in successive stages of metaphylactic therapy and from two groups of sows 10 and 18 weeks after the treatment ..."
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the treatment. MIC values of TMP and SMX were determined for a total of 352 strains. The presence of resistance genes (dfrA1, dfrA5, dfrA7, dfrA12, dfrA17, sul1, sul2, sul3) and class 1 and 2 integron-associated dfrA gene cassettes was tested. Resistance to TMP was very high during the administration
HIV post-exposure therapy for drug users in treatment
, 2000
"... Abstract The purpose of this study was to evaluate the attitudes of drug treatment program providers concerning human immunodeficiency virus (HIV) post-exposure therapy (PET) for drug users enrolled in drug treatment. This was a cross-sectional evaluation of drug treatment program providers in four ..."
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Abstract The purpose of this study was to evaluate the attitudes of drug treatment program providers concerning human immunodeficiency virus (HIV) post-exposure therapy (PET) for drug users enrolled in drug treatment. This was a cross-sectional evaluation of drug treatment program providers
Results 1 - 10
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215
