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Gene selection for cancer classification using support vector machines

by Isabelle Guyon, Jason Weston, Stephen Barnhill, Vladimir Vapnik, Nello Cristianini - Machine Learning
"... Abstract. DNA micro-arrays now permit scientists to screen thousands of genes simultaneously and determine whether those genes are active, hyperactive or silent in normal or cancerous tissue. Because these new micro-array devices generate bewildering amounts of raw data, new analytical methods must ..."
Abstract - Cited by 1115 (24 self) - Add to MetaCart
Abstract. DNA micro-arrays now permit scientists to screen thousands of genes simultaneously and determine whether those genes are active, hyperactive or silent in normal or cancerous tissue. Because these new micro-array devices generate bewildering amounts of raw data, new analytical methods must

Effective Mapping of Biomedical Text to the UMLS Metathesaurus: The MetaMap Program

by Alan R. Aronson , 2001
"... The UMLS® Metathesaurus®, the largest thesaurus in the biomedical domain, provides a representation of biomedical knowledge consisting of concepts classified by semantic type and both hierarchical and nonhierarchical relationships among the concepts. This knowledge has proved useful for many applica ..."
Abstract - Cited by 380 (4 self) - Add to MetaCart
applications including decision support systems, management of patient records, information retrieval (IR) and data mining. Gaining effective access to the knowledge is critical to the success of these applications. This paper describes MetaMap, a program developed at the National Library of Medicine (NLM

Measuring phase-synchrony in brain signals

by Eugenio Rodriguez, Jacques Martinerie, Francisco J. Varela - Hum. Brain Mapp , 1999
"... r r Abstract: This article presents, for the first time, a practical method for the direct quantification of frequency-specific synchronization (i.e., transient phase-locking) between two neuroelectric signals. The motivation for its development is to be able to examine the role of neural synchronie ..."
Abstract - Cited by 346 (6 self) - Add to MetaCart
coherence, PLS separates the phase and amplitude components and can be directly interpreted in the framework of neural integration. To validate synchrony values against background fluctuations, PLS uses surrogate data and thus makes no a priori assumptions on the nature of the experimental data. We also

A neuropsychological theory of multiple systems in category learning

by F. Gregory Ashby, Leola A. Alfonso-Reese, And U. Turken, Elliott M. Waldron - PSYCHOLOGICAL REVIEW , 1998
"... A neuropsychological theory is proposed that assumes category learning is a competition between separate verbal and implicit (i.e., procedural-learning-based) categorization systems. The theory assumes that the caudate nucleus is an important component of the implicit system and that the anterior ci ..."
Abstract - Cited by 340 (32 self) - Add to MetaCart
cingulate and prefrontal cortices are critical to the verbal system. In addition to making predictions for normal human adults, the theory makes specific predictions for children, elderly people, and patients suffering from Parkinson's disease, Huntington's disease, major depression, amnesia

Encryption and the loss of patient data

by Amalia R. Miller, Catherine E. Tucker - Journal of Policy Analysis and Management , 2011
"... Fast-paced IT advances have made it increasingly possible and useful for firms to collect data on their customers on an unprecedented scale. One downside of this is that firms can experience negative publicity and financial damage if their data are breached. This is particularly the case in the medi ..."
Abstract - Cited by 4 (2 self) - Add to MetaCart
in the medical sector, where we find empirical evidence that increased digitization of patient data is associated with more data breaches. The encryption of customer data is often presented as a potential solution, because encryp-tion acts as a disincentive for potential malicious hackers, and can minimize

Pragmatics of measuring recognition memory: Applications to dementia and amnesia.

by Joan Gay Snodgrass , June Corwin - Journal of Experimental Psychology: General, , 1988
"... SUMMARY This article has two purposes. The first is to describe four theoretical models of yesno recognition memory and present their associated measures of discrimination and response bias. These models are then applied to a set of data from normal subjects to determine which pairs of discriminati ..."
Abstract - Cited by 326 (0 self) - Add to MetaCart
SUMMARY This article has two purposes. The first is to describe four theoretical models of yesno recognition memory and present their associated measures of discrimination and response bias. These models are then applied to a set of data from normal subjects to determine which pairs

Cooperative Mining of Patient Data

by Niels Damgaard, Contact Prof, Brian H. Mayoh, Junping Du, Junping Du, Brian H. Mayoh, Brian H. Mayoh
"... In this paper, we use machine leaming schemes lR, FOIL, InductH and C5.0 to generate decision trees and rules from the examples in the medical dataset. Furthermore we have used an approach where neural networks generated by genetic algorithms were also used to classify the data. The aim of our study ..."
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: brian@daimi.aau.dk Cooperative Mining of Patient Data Junping Du, Brian H. Mayoh, NielsDamgaard Comp...

from individual patient data

by Sebastian Straube, Sheena Derry, R Andrew Moore, Jocelyn Paine, Henry J Mcquay
"... Background: Population mean changes are difficult to use in clinical practice. Responder analysis may be better, but needs validating for level of response and treatment duration. A consensus group has defined what constitutes minimal, moderate, and substantial benefit based on pain intensity and Pa ..."
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and Patient Global Impression of Change scores. Methods: We obtained individual patient data from four randomised double blind trials of pregabalin in fibromyalgia lasting eight to 14 weeks. We calculated response for all efficacy outcomes using any improvement ( ≥ 0%), minimal improvement ( ≥ 15%), moderate

patient data meta-analysis

by unknown authors
"... Protocol for a systematic r ..."
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Protocol for a systematic r

Use of Patient Data for QualityControlof

by Allenh Reed , 1969
"... The average.of.normals quality-control method is examined mathematically. Two modifications are proposed. After modification, the essential un-changed feature of the method is the idea of censoring the laboratory test results so that only means of test values inside the normal range are plotted on t ..."
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in the clinical laboratory. Q UALITY CONTROL charts based on control sam-ples have been used routinely in the clinical laboratory for some time (1, 2). More recently, several writers have advocated methods for moni-toring the routine precision of a laboratory test by using results from patient data (3-6). My
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