paternally derived (or vice versa). Parental antagonism favours the evolution of alleles that are expressed only when maternally derived or only when paternally derived (genomic imprinting). 1.

Parental antagonism and parent−offspring co-adaptation

Sexual antagonism occurs when an allele is beneficial in one sex but costly in the other. Parental antagonism occurs when an allele is beneficial when inherited from one sex but costly when inherited from the other because of fitness interactions among kin. Sexual and parental antagonisms together

lines, compared with the parental Ci67 VP40. Ci67 VP40 is also demonstrated to target the activation of kinase Jak1. A single change at VP40 residue 79 was found to be suf-ficient for the increased VP40 IFN antagonism. These data argue that VP40 IFN-antagonist activity plays a key role in MARV

‐induced deletions at CAG repeat tract. To test the role of CSB in vivo, we measured intergenerational and somatic expansion of CAG tracts in HD mice lacking CSB, OGG1, or both. We provide evidence that CSB protects CAG repeats from expansion by either active reduction of the tract length during parent

and ABCG2 in vitro. Methodology and Principal Findings: MDR cancer cells overexpressing ABCC1 or ABCG2 and their sensitive parental cell lines were used. MTT assay showed that vandetanib had moderate and almost equal-potent anti-proliferative activity in both sensitive parental and MDR cancer cells

was derived by Foley et al. (1965) from the peripheral blood of a patient with acute lymphoblastic leukaemia (ALL). When tested by Norman & Thompson (1977) CCRF-CEM was only partially sensitive to glucocorticoids, but Clone C7, isolated from the parental cell line, was lysed by pharmacological

, and became increasingly avoidant over time. A path model, guided by a Process ϫ Person ϫ Context ϫ Time model, revealed that low parental self-efficacy heightened by parenting stress and children's dysregulated temperament was directly related to the escalating-antagonism pattern. Punitive parenting

-helicity of these peptides was demonstrated by circular dichroism spectroscopy in the presence of liposomes. CP29 was shown to have activity against gram-negative bacteria that was similar to or better than those of the parent peptides, and CP26 had similar activity. CP29 had cytoplasmic membrane permeabilization activity

-offspring relationship. Kowakare is the psychosomatic development of the relationship as the process of accumulation in the otherness of offspring. Early human Kowakare has two frameworks, biological interbody antagonism and socio-cultural allomothering compensating the antagonism. Some features of feeding