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Classification by pairwise coupling

by Trevor Hastie, Robert Tibshirani , 1998
"... We discuss a strategy for polychotomous classification that involves estimating class probabilities for each pair of classes, and then coupling the estimates together. The coupling model is similar to the Bradley-Terry method for paired comparisons. We study the nature of the class probability estim ..."
Abstract - Cited by 378 (0 self) - Add to MetaCart
We discuss a strategy for polychotomous classification that involves estimating class probabilities for each pair of classes, and then coupling the estimates together. The coupling model is similar to the Bradley-Terry method for paired comparisons. We study the nature of the class probability

Sequential data assimilation with a nonlinear quasi-geostrophic model using Monte Carlo methods to forecast error statistics

by Geir Evensen - J. Geophys. Res , 1994
"... . A new sequential data assimilation method is discussed. It is based on forecasting the error statistics using Monte Carlo methods, a better alternative than solving the traditional and computationally extremely demanding approximate error covariance equation used in the extended Kalman filter. The ..."
Abstract - Cited by 800 (23 self) - Add to MetaCart
. A new sequential data assimilation method is discussed. It is based on forecasting the error statistics using Monte Carlo methods, a better alternative than solving the traditional and computationally extremely demanding approximate error covariance equation used in the extended Kalman filter

A Fast Algorithm for Particle Simulations

by L. Greengard, V. Rokhlin , 1987
"... this paper to the case where the potential (or force) at a point is a sum of pairwise An algorithm is presented for the rapid evaluation of the potential and force fields in systems involving large numbers of particles interactions. More specifically, we consider potentials of whose interactions a ..."
Abstract - Cited by 1152 (19 self) - Add to MetaCart
are Coulombic or gravitational in nature. For a the form system of N particles, an amount of work of the order O(N 2 ) has traditionally been required to evaluate all pairwise interactions, un- F5F far 1 (F near 1F external ), less some approximation or truncation method is used. The algorithm of the present

Text Categorization with Support Vector Machines: Learning with Many Relevant Features

by Thorsten Joachims , 1998
"... This paper explores the use of Support Vector Machines (SVMs) for learning text classifiers from examples. It analyzes the particular properties of learning with text data and identifies, why SVMs are appropriate for this task. Empirical results support the theoretical findings. SVMs achieve substan ..."
Abstract - Cited by 2303 (9 self) - Add to MetaCart
substantial improvements over the currently best performing methods and they behave robustly over a variety of different learning tasks. Furthermore, they are fully automatic, eliminating the need for manual parameter tuning.

Gene selection for cancer classification using support vector machines

by Isabelle Guyon, Jason Weston, Stephen Barnhill, Vladimir Vapnik, Nello Cristianini - Machine Learning
"... Abstract. DNA micro-arrays now permit scientists to screen thousands of genes simultaneously and determine whether those genes are active, hyperactive or silent in normal or cancerous tissue. Because these new micro-array devices generate bewildering amounts of raw data, new analytical methods must ..."
Abstract - Cited by 1115 (24 self) - Add to MetaCart
based on Recursive Feature Elimination (RFE). We demonstrate experimentally that the genes selected by our techniques yield better classification performance and are biologically relevant to cancer. In contrast with the baseline method, our method eliminates gene redundancy automatically and yields

MAFFT version 5: improvement in accuracy of multiple sequence alignment

by Kazutaka Katoh, Kei-ichi Kuma, Hiroyuki Toh, Takashi Miyata - NUCLEIC ACIDS RES , 2005
"... The accuracy of multiple sequence alignment pro-gram MAFFT has been improved. The new version (5.3) of MAFFT offers new iterative refinement options, H-INS-i, F-INS-i and G-INS-i, in which pairwise alignment information are incorporated into objective function. These new options of MAFFT showed high ..."
Abstract - Cited by 801 (5 self) - Add to MetaCart
The accuracy of multiple sequence alignment pro-gram MAFFT has been improved. The new version (5.3) of MAFFT offers new iterative refinement options, H-INS-i, F-INS-i and G-INS-i, in which pairwise alignment information are incorporated into objective function. These new options of MAFFT showed

A Bayesian approach to filtering junk E-mail

by Mehran Sahami, Susan Dumais, David Heckerman, Eric Horvitz - PAPERS FROM THE 1998 WORKSHOP, AAAI , 1998
"... In addressing the growing problem of junk E-mail on the Internet, we examine methods for the automated construction of filters to eliminate such unwanted messages from a user’s mail stream. By casting this problem in a decision theoretic framework, we are able to make use of probabilistic learning m ..."
Abstract - Cited by 545 (6 self) - Add to MetaCart
In addressing the growing problem of junk E-mail on the Internet, we examine methods for the automated construction of filters to eliminate such unwanted messages from a user’s mail stream. By casting this problem in a decision theoretic framework, we are able to make use of probabilistic learning

A direct approach to false discovery rates

by John D. Storey , 2002
"... Summary. Multiple-hypothesis testing involves guarding against much more complicated errors than single-hypothesis testing. Whereas we typically control the type I error rate for a single-hypothesis test, a compound error rate is controlled for multiple-hypothesis tests. For example, controlling the ..."
Abstract - Cited by 775 (14 self) - Add to MetaCart
the false discovery rate FDR traditionally involves intricate sequential p-value rejection methods based on the observed data. Whereas a sequential p-value method fixes the error rate and estimates its corresponding rejection region, we propose the opposite approach—we fix the rejection region

Improved prediction of signal peptides -- SignalP 3.0

by Jannick Dyrløv Bendtsen, Henrik Nielsen, Gunnar von Heijne, Søren Brunak - J. MOL. BIOL. , 2004
"... We describe improvements of the currently most popular method for prediction of classically secreted proteins, SignalP. SignalP consists of two different predictors based on neural network and hidden Markov model algorithms, where both components have been updated. Motivated by the idea that the cle ..."
Abstract - Cited by 654 (7 self) - Add to MetaCart
peptide discrimination improvement is mainly due to the elimination of false positive predictions, as well as the introduction of a new discrimination score for the neural network. The new method has also been benchmarked against other available methods. Predictions can be made at the publicly available

Classical negation in logic programs and disjunctive databases

by Michael Gelfond, Vladimir Lifschitz - New Generation Computing , 1991
"... An important limitation of traditional logic programming as a knowledge representation tool, in comparison with classical logic, is that logic programming does not allow us to deal directly with incomplete information. In order to overcome this limitation, we extend the class of general logic progra ..."
Abstract - Cited by 1044 (73 self) - Add to MetaCart
programs by including classical negation, in addition to negation-as-failure. The semantics of such extended programs is based on the method of stable models. The concept of a disjunctive database can be extended in a similar way. We show that some facts of commonsense knowledge can be represented by logic
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