This is a digitized copy derived from an ACM copyrighted work. It is not guaranteed to be an accurate copy of the author's original work. This paper develops Brinch-Hansen's concept of a monitor as a method of structuring an operating system. It introduces a form of synchronization

Normal plantar weight distribution pattern and its variations with change of functional position and its comparison with patients of knee osteoarthritis

Un nuevo método de cromatografía de líquidos de alto rendimiento y de fase inversa para la determinación de flutamida en liposomas, plasma de sangre de rata y formas de dosificación en comprimidos A new reverse-phase high performance liquid chromatographic method for determination of flutamide in liposomes, rat blood plasma and tablet dosage forms

ABSTRACT: The Island of Mauritius was affected by a large scale epidemic outbreak of Chikungunya Fever (CHIKF) from February to April 2006. It was observed that this epidemic was associated with an excess mortality during the months of March to May 2006 in Mauritius. This study was aimed to analyze the gender and age group distribution of the excess mortality. Population and mortality data were obtained from the Mauritius Central Statistics Office for the years 2000 to 2006. The excess monthly mortality was computed for 2006 and the distribution of excess mortality according to gender and age groups was analyzed. For both genders combined, the excess mortality was 91.5 % in the age group ≥50 years. For the ≥ 50-year age group, the total male excess death rate (EDR) exceeded the total female EDR by 66%. Our results indicate that CHIKF is associated with an increased mortality particularly in the ≥ 50-year age group with males being more vulnerable than females to mortality. Although there have been reports of CHIKF related deaths in other studies, the profile of the excess mortality during a CHIKF outbreak has not been previously described.

Treatment to targets in type 2 diabetics: analysis of out-patients practice at a remote Western Nigerian hospital

ABSTRACT: Nutritional inadequacy leads to health problems, especially during the period of increased demand. Adolescents are a potential group in view of rapid growth and maturation which demands extra nutrients. With the multitude of social customs and beliefs cited against adolescents especially adolescent girls it is no wonder that they form the vulnerable group of under nutrition. With poor socio economic status, hostile living conditions and food influenced by vagaries of nature, adolescents living at hills form the distinct group to be studied. This cross-sectional prevalence study included 45 adolescent girls of age group 12-19 years residing in hills of Garhwal. The outcome measures for nutritional status were stunting, thinness and proportion of underweight/under nutrition. In this study 34.61 % of adolescents ’ girls were found to be stunted. The stunting was more (33.33%) in 16 to 19 years of age group. The overall prevalence of thinness was 43.47%. However percentage of thinness was higher (56.25%) in the lower age group (12-15 years). Under nutrition was prevalent in similar proportions in both the age groups with> 50 % of the rural adolescent girls having less than 3rd percentile of weight for age by NCHS standards. The prevalence of stunting, thinness and underweight was high among adolescent girls living at high altitudes. In this regard special attention should be paid to the girls of hills and specific strategies should be formulated for meeting their nutritional demands.

ABSTRACT: The aims of the present study are to observe the prevalence of hypothyroidism (both subclinical and overt hypothyroidism), its association with dyslipidemia and whether replacement therapy with thyroid hormone has an effect on plasma lipid profile of hypothyroid patients. This prospective study of one-year duration recruited 232 clinically suspected patients belonging to both sexes and age group between 20-70 years attending OPD of endocrinology department of MLN Medical College, Allahabad. Patients were screened for T3, T4 and TSH and those who were euthyroid (52 cases) were excluded from the study. Thus, the present study included only 180 newly diagnosed cases of hypothyroidism. Levothyroxine replacement therapy was administered and patients were assessed every 3-4 months for an effect on lipid profile and body mass index during the study period. In both subclinical and overt hypothyroidism associated with dyslipidemia, replacement therapy with levothyroxine resulted in reversal to normal in significant number of cases. Although majority of hypothyroid cases were overweight yet therapy with levothyroxine caused no significant changes in BMI in all grades of obesity.

A comparative study to determine the clinical efficacy of Ramipril versus combination of Ramipril and Telmisartan in reducing microalbuminuria associated with grade 2 hypertension

ABSTRACT: The objective of our research project was screening of various highly specific substrates of Acetoxy Drug: Protein Transacytylase (M.TAase) for antimycobacterial activity. Mycobacterial culture was done in Middlebrook’s 7H9 media. Protein purification (Mycobacterial Tranacetylase, M.TAase) was done by ion exchange chromatography and its demonstration was done on SDS- polyacrylamide gel electrophoresis (SDS-PAGE) and western blot. Middlebrook’s 7H9 broth was procured from Becton Dickinson. CM-Sepharose, DEAE-Sepharose and Q-Sephharose were purchased from Amersham Pharmacia. Anti acetyl lysine polyclonal antibody was purchased from Cell Signaling. The Middlebrook 7H9 medium was used for M. smegmatis culture. The media was prepared according to the manufacturer’s instructions. The various Polyphenol acetate compounds were tested for their antimycobacterial activities. Minimal inhibitory concentrations (MIC) were calculated by Alamar blue dye assay method. The GST protein was used as a receptor protein and purified Mycobacterial Glutamine Synthetase (GS) as TAase for acetylation by DAMC. To demonstrate the TAase catalyzed acetylation of GST by DAMC, purified M.TAase (GS) was preincubated with GST and

ABSTRACT: A versatile assessment technique used in classroom for quick and simple feedback is ‘One-Minute paper’. It provides real-time feedback from class and enables the teacher to find out if students have recognized the main points in a class session. The objectives of the study were to employ one-minute paper for post-graduate students during a continuous medical education (CME) program lecture, to assess its effectiveness for achievement of objectives and learning ability of the students, to analyze the questioning pattern of the students for the topic and to obtain feedback on participant’s perception on use of ‘one-minute paper’. The study was employed for one-hour lecture in CME program for post-graduate students. One-Minute paper was employed for the topic ‘Phenylketonuria’. The lecture was sub-divided into five components and the response sheet was designed accordingly. The delivery time for each component varied between 8 to 12 minutes. At the end of each component, 2 minutes was given for the participants to respond to two questions- what was the most important thing they learnt during this session and what important question remains unanswered? Analysis of response was carried out to know achievement of objectives, association of learning ability and