Changes to Management Committee and Newsletter Editorship Peter Hendriks is now Director of the CRLC,  replacing Cynthia Allen after two terms in this role. Cynthia will take over the editorship of The Chameleon. Thanks to outgoing editor Harold Koch for his fine work on past editions and for coediting this edition.

8. Publish with the CRLC! Many thanks to Rachel Hendery for her substantial assistance to the editor (Cynthia Allen)  in the production of this edition. Thanks also to Rachel for serving as the student representative on the CRLC Management Committee until the successful termination of her status as a PhD candidate (see Profile).  Thanks to Bevan Barrett for taking up the position of student representative.

Note: permission from the proper authorities has been granted to use all reprinted information.

Two kinds of contemporary developments in cryptography are examined. Widening applications of teleprocessing have given rise to a need for new types of cryptographic systems, which minimize the need for secure key distribution channels and supply the equivalent of a written signature. This paper

It has long been recognized that personality test scores are influenced by non-test-relevant response determinants. Wiggins and Rumrill (1959) distinguish three approaches to this problem. Briefly, interest in the problem of response distortion has been concerned with attempts at statistical correction for "faking good " or "faking bad " (Meehl & Hathaway, 1946), the analysis of response sets (Cron-bach, 1946,1950), and ratings of the social de-sirability of personality test items (Edwards, 19 5 7). A further distinction can be made, how-ever, which results in a somewhat different division of approaches to the question of re-sponse distortion. Common to both the Meehl

cases is much more sensitive to weak but biologically relevant sequence similarities. PSI-BLAST is used to uncover several new and interesting members of the BRCT superfamily.

We examine properties of residual-based tests for the null of no cointegration for dynamic panels in which both the short-run dynamics and the long-run slope coefficients are permitted to be heterogeneous across individual members of the panel+ The tests also allow for individual heterogeneous

The rapid growth of the World-Wide Web poses unprecedented scaling challenges for general-purpose crawlers and search engines. In this paper we describe a new hypertext resource discovery system called a Focused Crawler. The goal of a focused crawler is to selectively seek out pages

INTRODUCTION A logo is "a single piece of type bearing two or more usually separate elements" [1]. In this paper, we use logos to display aligned sets of sequences. Sequence logos concentrate the following information into a single graphic [2]: 1. The general consensus of the sequences. National Cancer Institute, Frederick Cancer Research and Development Center, Laboratory of Mathematical Biology, P. O. Box B, Frederick, MD 21701. Internet addresses: toms@ncifcrf.gov and stephens@ncifcrf.gov. y corresponding author 1 2. The order of predominance of the residues at every position. 3. The relative frequencies of every residue at every position. 4. The amount of information present at every position in the sequence, measured in bits. 5. An initiation point, cut point, or other significant location (if appropriate) . Any aligned set of DNA, RNA or protein sequences can be represented using this technique. CREATION OF BINDING S

of its members. Web servers are unable to learn the true source of a request because it is equally likely to have originated from any member of the crowd, and even collaborating crowd members cannot distinguish the originator of a request from a member who is merely forwarding the request on behalf