Results 1 - 10 of 36,503

Database resources of the National Center for Biotechnology Information

by David L. Wheeler, Tanya Barrett, Dennis A. Benson, Stephen H. Bryant, Kathi Canese, Vyacheslav Chetvernin, Deanna M. Church, Michael Dicuccio, Ron Edgar, Scott Federhen, Lewis Y. Geer, Yuri Kapustin, Oleg Khovayko, David L, David J. Lipman, Thomas L. Madden, Donna R. Maglott, James Ostell, Vadim Miller, Kim D. Pruitt, Gregory D. Schuler, Edwin Sequeira, Steven T. Sherry, Karl Sirotkin, Re Souvorov, Grigory Starchenko, Roman L. Tatusov, Tatiana A. Tatusova, Lukas Wagner, Eugene Yaschenko - Nucleic Acids Res , 2008
"... In addition to maintaining the GenBankÒ nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI’s Web site. NCBI resources include Entrez, ..."
Abstract - Cited by 964 (15 self) - Add to MetaCart
In addition to maintaining the GenBankÒ nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI’s Web site. NCBI resources include Entrez,

NCBI reference sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

by Kim D. Pruitt, Tatiana Tatusova, Donna R. Maglott - Nucleic Acids Res , 2005
"... transcripts and proteins ..."
Abstract - Cited by 586 (6 self) - Add to MetaCart
transcripts and proteins

The KEGG resource for deciphering the genome

by Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, Yasushi Okuno, Masahiro Hattori - Nucleic Acids Res , 2004
"... A grand challenge in the post-genomic era is a complete computer representation of the cell and the organism, which will enable computational prediction of higher-level complexity of cellular processes and organism behavior from genomic information. Toward this end we have been developing a knowledg ..."
Abstract - Cited by 504 (24 self) - Add to MetaCart
A grand challenge in the post-genomic era is a complete computer representation of the cell and the organism, which will enable computational prediction of higher-level complexity of cellular processes and organism behavior from genomic information. Toward this end we have been developing a knowledge-based approach for network prediction, which is to predict, given a complete set of genes in the genome, the protein interaction networks that are responsible for various cellular processes. KEGG at

Identification of Single Nucleotide Polymorphisms and associated Disease Genes using NCBI resources

by Navreet Kaur, Dr. Amardeep Singh
"... Abstract — Single Nucleotide Polymorphisms (SNP) are the most common and simplest form of variation associated with genetic diseases. SNPs are responsible for more than half of the genetic polymorphisms known to cause inherited diseases. The SNPs are single base changes in the DNA sequence which are ..."
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development. The paper focuses on the method of detection of SNPs and associated disease genes using the National Center for Biotechnology Information (NCBI) resources. The BLAST, NCBI Map Viewer, dbSNP and Cn3D tools have been used to identify the SNPs and associated genes aligning the given Expressed

Information resources at the National Center for Biotechnology Information

by Eric W. Sayers, Tanya Barrett, Dennis A. Benson, Evan Bolton, Stephen H. Bryant, Kathi Canese, Vyacheslav Chetvernin, Deanna M. Church, Michael Dicuccio, Scott Federhen, Michael Feolo, Lewis Y. Geer, Wolfgang Helmberg, Yuri Kapustin, David L, David J. Lipman, Zhiyong Lu, Thomas L. Madden, Tom Madej, Donna R. Maglott, Aron Marchler-bauer, Vadim Miller, Ilene Mizrachi, James Ostell, Anna Panchenko, Kim D. Pruitt, Gregory D. Schuler, Edwin Sequeira, Re Souvorov, Grigory Starchenko, Tatiana A. Tatusova, Lukas Wagner, Yanli Wang, W. John Wilbur, Eugene Yaschenko, Jian Ye - Nucleic Acids Res , 2009
"... In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made avail-able through the NCBI web site. NCBI resources include Entrez, the E ..."
Abstract - Cited by 321 (17 self) - Add to MetaCart
In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made avail-able through the NCBI web site. NCBI resources include Entrez

Database resources of the National Center for Biotechnology Information NCBI Resource Coordinators*y

by Programming Utilities , 2013
"... In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI, ..."
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In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI,

Pfam protein families database

by Robert D. Finn, John Tate, Jaina Mistry, Penny C. Coggill, Stephen John Sammut, Hans-rudolf Hotz, Goran Ceric, Kristoffer Forslund, Sean R. Eddy, Erik L. L. Sonnhammer, Alex Bateman - Nucleic Acids Research, 2008, 36(Database issue): D281–D288
"... Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam (22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI GenP ..."
Abstract - Cited by 748 (13 self) - Add to MetaCart
Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam (22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI Gen

2005 MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res

by Kazutaka Katoh, Kei-ichi Kuma, Hiroyuki Toh, Takashi Miyata
"... The accuracy of multiple sequence alignment pro-gram MAFFT has been improved. The new version (5.3) of MAFFT offers new iterative refinement opti-ons, H-INS-i, F-INS-i and G-INS-i, in which pairwise alignment information are incorporated into objective function. These new options of MAFFT showed hig ..."
Abstract - Cited by 788 (5 self) - Add to MetaCart
database. Such improvement was gen-erally observed for most methods, but remarkably large for the new options of MAFFT proposed here. Thus, we made a Ruby script, mafftE.rb, which aligns the input sequences together with their close homo-logues collected from SwissProt using NCBI-BLAST.

From genomics to chemical genomics: new developments in KEGG

by Minoru Kanehisa, Susumu Goto, Masahiro Hattori, Kiyoko F. Aoki-kinoshita, Masumi Itoh, Shuichi Kawashima, Toshiaki Katayama, Michihiro Araki, Mika Hirakawa - Nucleic Acids Res , 2006
"... The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interactions with the environment, as well as for medical, industrial and other practical applications. The KEGG resource ..."
Abstract - Cited by 517 (30 self) - Add to MetaCart
The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interactions with the environment, as well as for medical, industrial and other practical applications. The KEGG resource

Clone DB: an integrated NCBI resource for clone-associated data

by Valerie A. Schneider, Hsiu-chuan Chen, Cliff Clausen, Peter A. Meric, Zhigang Zhou, Nathan Bouk, Nora Husain, Donna R. Maglott, Deanna M. Church - Nucleic Acids Res , 2013
"... clone/) is an integrated resource providing informa-tion about and facilitating access to clones, which serve as valuable research reagents in many fields, including genome sequencing and variation analysis. Clone DB represents an expansion and replacement of the former NCBI Clone Registry and has r ..."
Abstract - Cited by 2 (0 self) - Add to MetaCart
clone/) is an integrated resource providing informa-tion about and facilitating access to clones, which serve as valuable research reagents in many fields, including genome sequencing and variation analysis. Clone DB represents an expansion and replacement of the former NCBI Clone Registry and has
Results 1 - 10 of 36,503