consecutive fashion allowed control over reaction parameters leading to fast optimisation. The performance of Heck reactions in multistep procedures was not as successful as in the single step coupling, whereas the ring-closing metathesis proved to be successful in the production of the desired compounds

The dogma of cancer biology is that tumours arise in a multistep fashion, and colon cancer has been the paradigm of this type of model. It is no surprise that the same model has been adopted in other cancer types, and breast

Summary. In this paper we propose a simple multistep regression smoother which is constructed in a boosting fashion, by learning the Nadaraya–Watson estimator with L2Boosting. Differently from the usual approach, we do not focus on L2Boosting for ever. Given a kernel smoother as a learner, we

Abstract—In the considered linear Gaussian sensor scheduling prob-lem, only one sensor out of a set of sensors performs a measurement. To minimize the estimation error over multiple time steps in a com-putationally tractable fashion, the so-called information-based pruning algorithm is proposed

Abstract: A multistep method with matricial coefficients is developed. It can be used to solve stiff initial value problems of the form y’ = Ay + g(x,y). This method bears the nature of the classical Adams-Bashforth-Moulton PC formula and can be shown to be consistent, convergent and A-stable. A

Background and Purpose: Current views on B-cell lymphoma genesis suggest that several exogenous factors, acting in a multistep fashion upon a predisposing condition, may be involved in B-cell clonal expansion, a potentially prelymphomatous stage. This study was done to investigate the extrahepatic

Ovalbumin (OVA) genetically fused to protein sigma 1 (ps1) results in tolerance to both OVA and ps1. Ps1 binds in a multistep fashion, involving both protein- and carbohydrate-based receptors. To assess the relative ps1 components responsible for inducing tolerance and the importance of its sialic

For many applications—including recognizing malware variants, determining the range of system versions vulnerable to a given attack, testing defense mechanisms, and filtering multi-step attacks—it can be highly useful to mimic an existing system while interacting with a live host on the network. We

. The results of pulse-chase experiments indicated that the post-translational processing of large prosequences proceeds in a multistep fashion to produce the mature enzymes. Processing intermediates for EP-B are observed both in the aleurone layers and surrounding incubation medium, but only mature EP

This work addresses the need for stateful dataflow programs that can rapidly sift through huge, evolving data sets. These data-intensive applications perform complex multi-step computations over successive generations of data inflows, such as weekly web crawls, daily image/video uploads, log files