We provide formal definitions and efficient secure techniques for • turning noisy information into keys usable for any cryptographic application, and, in particular, • reliably and securely authenticating biometric data. Our techniques apply not just to biometric information, but to any keying

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This paper describes a distributed, linear-time algorithm for localizing sensor network nodes in the presence of range measurement noise and demonstrates the algorithm on a physical network. We introduce the probabilistic notion of robust quadrilaterals as a way to avoid flip ambiguities that otherwise corrupt localization computations. We formulate the localization problem as a two-dimensional graph realization problem: given a planar graph with approximately known edge lengths, recover the Euclidean position of each vertex up to a global rotation and translation. This formulation is applicable to the localization of sensor networks in which each node can estimate the distance to each of its neighbors, but no absolute position reference such as GPS or fixed anchor nodes is available. We implemented the algorithm on a physical sensor network and empirically assessed its accuracy and performance. Also, in simulation, we demonstrate that the algorithm scales to large networks and handles real-world deployment geometries. Finally, we show how the algorithm supports localization of mobile nodes.

There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling efficiency between the two fluorescent dyes). The term normalization refers to the process of removing such variation. A constant adjustment is often used to force the distribution of the intensity log ratios to have a median of zero for each slide. However, such global normalization approaches are not adequate in situations where dye biases can depend on spot overall intensity and/or spatial location within the array. This article proposes normalization methods that are based on robust local regression and account for intensity and spatial dependence in dye biases for different types of cDNA microarray experiments. The selection of appropriate controls for normalization is discussed and a novel set of controls (microarray sample pool, MSP) is introduced to aid in intensity-dependent normalization. Lastly, to allow for comparisons of expression levels across slides, a robust method based on maximum likelihood estimation is proposed to adjust for scale differences among slides.

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prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive only for your personal, non-commercial use. Please contact the publisher regarding any further use of this work. Publisher contact information may

you have obtained prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive only for your personal, non-commercial use. Please contact the publisher regarding any further use of this work. Publisher contact

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