for the quality of the model. Strategies and tools are described that help to alleviate this problem. These simplify the model-building process, quantify the goodness of fit of the model on a per-residue basis and locate possible errors in pep-tide and side-chain conformations.

A number of techniques have been developed for reconstructing surfaces by integrating groups of aligned range images. A desirable set of properties for such algorithms includes: incremental updating, representation of directional uncertainty, the ability to fill gaps in the reconstruction, and robustness in the presence of outliers. Prior algorithms possess subsets of these properties. In this paper, we present a volumetric method for integrating range images that possesses all of these properties. Our volumetric representation consists of a cumulative weighted signed distance function. Working with one range image at a time, we first scan-convert it to a distance function, then combine this with the data already acquired using a simple additive scheme. To achieve space efficiency, we employ a run-length encoding of the volume. To achieve time efficiency, we resample the range image to align with the voxel grid and traverse the range and voxel scanlines synchronously. We generate the f...

, knowledge content has been processed by the students. In this chapter we offer a suggestion for how to escape the pattern of reinventing the familiar with educational technology. Knowledge-building discourse is at the heart of the superior education that we have in mind. We argue that the classroom needs

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Motivation: Homology models of proteins are of great interest for planning and analyzing biological experiments when no experimental three-dimensional structures are available. Building homology models requires specialized programs and up-to-date sequence and structural databases. Integrating all

The proliferation of mobile computing devices and local-area wireless networks has fostered a growing interest in location-aware systems and services. In this paper we present RADAR, a radio-frequency (RF) based system for locating and tracking users inside buildings. RADAR operates by recording

for enterprises as diverse as the automatic construction of statistical models for the grammar of the written and the colloquial spoken language, the development of explicit formal theories of the differing grammars of writing and speech, the investigation of prosodic phenomena in speech, and the evaluation

, and efficient instrumentation. Instrumentation tools (called Pintools) are written in C/C++ using Pin’s rich API. Pin follows the model of ATOM, allowing the tool writer to analyze an application at the instruction level without the need for detailed knowledge of the underlying instruction set. The API

Dryad is a general-purpose distributed execution engine for coarse-grain data-parallel applications. A Dryad applica-tion combines computational “vertices ” with communica-tion “channels ” to form a dataflow graph. Dryad runs the application by executing the vertices of this graph on a set of available computers, communicating as appropriate through files, TCP pipes, and shared-memory FIFOs. The vertices provided by the application developer are quite simple and are usually written as sequential programs with no thread creation or locking. Concurrency arises from Dryad scheduling vertices to run simultaneously on multi-ple computers, or on multiple CPU cores within a computer. The application can discover the size and placement of data at run time, and modify the graph as the computation pro-gresses to make efficient use of the available resources. Dryad is designed to scale from powerful multi-core sin-gle computers, through small clusters of computers, to data centers with thousands of computers. The Dryad execution engine handles all the difficult problems of creating a large distributed, concurrent application: scheduling the use of computers and their CPUs, recovering from communication or computer failures, and transporting data between ver-tices.

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