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The Retinoblastoma Protein and Cell-Cycle Control

by Robert A. Weinberg - Cell , 1995
"... pRB, the product of the retinoblastoma tumor suppressor gene, operates in the midst of the cell cycle clock appara-tus. Its main role is to act as a signal transducer connecting the cell cycle clock with the transcriptional machinery. In this role, pRB allows the clock to control the expression of b ..."
Abstract - Cited by 429 (5 self) - Add to MetaCart
pRB, the product of the retinoblastoma tumor suppressor gene, operates in the midst of the cell cycle clock appara-tus. Its main role is to act as a signal transducer connecting the cell cycle clock with the transcriptional machinery. In this role, pRB allows the clock to control the expression

Information-Based Objective Functions for Active Data Selection

by David J.C. MacKay - Neural Computation
"... Learning can be made more efficient if we can actively select particularly salient data points. Within a Bayesian learning framework, objective functions are discussed which measure the expected informativeness of candidate measurements. Three alternative specifications of what we want to gain infor ..."
Abstract - Cited by 428 (4 self) - Add to MetaCart
Learning can be made more efficient if we can actively select particularly salient data points. Within a Bayesian learning framework, objective functions are discussed which measure the expected informativeness of candidate measurements. Three alternative specifications of what we want to gain

Robust convex optimization

by A. Ben-tal, A. Nemirovski - Mathematics of Operations Research , 1998
"... We study convex optimization problems for which the data is not specified exactly and it is only known to belong to a given uncertainty set U, yet the constraints must hold for all possible values of the data from U. The ensuing optimization problem is called robust optimization. In this paper we la ..."
Abstract - Cited by 416 (21 self) - Add to MetaCart
lay the foundation of robust convex optimization. In the main part of the paper we show that if U is an ellipsoidal uncertainty set, then for some of the most important generic convex optimization problems (linear programming, quadratically constrained programming, semidefinite programming and others

The Determinants of Credit Spread Changes.

by Pierre Collin-Dufresne , Robert S Goldstein , J Spencer Martin , Gurdip Bakshi , Greg Bauer , Dave Brown , Francesca Carrieri , Peter Christoffersen , Susan Christoffersen , Greg Duffee , Darrell Duffie , Vihang Errunza , Gifford Fong , Mike Gallmeyer , Laurent Gauthier , Rick Green , John Griffin , Jean Helwege , Kris Jacobs , Chris Jones , Andrew Karolyi , Dilip Madan , David Mauer , Erwan Morellec , Federico Nardari , N R Prabhala , Tony Sanders , Sergei Sarkissian , Bill Schwert , Ken Singleton , Chester Spatt , René Stulz - Journal of Finance , 2001
"... ABSTRACT Using dealer's quotes and transactions prices on straight industrial bonds, we investigate the determinants of credit spread changes. Variables that should in theory determine credit spread changes have rather limited explanatory power. Further, the residuals from this regression are ..."
Abstract - Cited by 422 (2 self) - Add to MetaCart
at both the individual firm level (see, for example, Kwan (1996)) and portfolio level (see, for example, Blume, Keim and Patel (1991), and Cornell and Green (1991)). These studies focus on corporate bond returns, or yield changes. The main conclusions of these papers are: (1) high-grade bonds behave

Internet traffic engineering by optimizing OSPF weights

by Bernard Fortz - in Proc. IEEE INFOCOM , 2000
"... Abstract—Open Shortest Path First (OSPF) is the most commonly used intra-domain internet routing protocol. Traffic flow is routed along shortest paths, splitting flow at nodes where several outgoing links are on shortest paths to the destination. The weights of the links, and thereby the shortest pa ..."
Abstract - Cited by 403 (13 self) - Add to MetaCart
path routes, can be changed by the network operator. The weights could be set proportional to their physical distances, but often the main goal is to avoid congestion, i.e. overloading of links, and the standard heuristic recommended by Cisco is to make the weight of a link inversely proportional

Embedded root phenomena, assertion, presupposition, and main point of utterance

by Kristine Bentzen - Workshop on Root Phenomena , 2009
"... Main claims of this talk: 1. The assertion/presupposition distinction is not crucial for the availability of embedded root phenomena. 2. The potential independent communicative contribution of the clause is relevant for whether syntactic root phenomena are available or not. 3. (Embedded) syntactic r ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
Main claims of this talk: 1. The assertion/presupposition distinction is not crucial for the availability of embedded root phenomena. 2. The potential independent communicative contribution of the clause is relevant for whether syntactic root phenomena are available or not. 3. (Embedded) syntactic

Concentration Of Measure And Isoperimetric Inequalities In Product Spaces

by Michel Talagrand , 1995
"... The concentration of measure phenomenon in product spaces roughly states that, if a set A in a product# N of probability spaces has measure at least one half, "most" of the points of# N are "close" to A. We proceed to a systematic exploration of this phenomenon. The meaning o ..."
Abstract - Cited by 376 (4 self) - Add to MetaCart
The concentration of measure phenomenon in product spaces roughly states that, if a set A in a product# N of probability spaces has measure at least one half, "most" of the points of# N are "close" to A. We proceed to a systematic exploration of this phenomenon. The meaning

The Object-Oriented Database System Manifesto

by Malcolm Atkinson, François Bancilhon, David DeWitt, Klaus Dittrich, David Maier, Stanley Zdonik , 1989
"... This paper attempts to define an object-oriented database system. It describes the main features and characteristics that a system must have to qualify as an objectoriented database system. We have separated these characteristics into three groups: ffl Mandatory, the ones the system must satisfy in ..."
Abstract - Cited by 361 (5 self) - Add to MetaCart
This paper attempts to define an object-oriented database system. It describes the main features and characteristics that a system must have to qualify as an objectoriented database system. We have separated these characteristics into three groups: ffl Mandatory, the ones the system must satisfy

Journal of Business Cases and Applications Total points are not, Page 1 Total points are not the main point

by Bob Wheatley
"... This case study provides students with the opportunity to use descriptive statistics tools to compare the “competitiveness ” of the football series between several southern universities. In addition, more advanced topics such as hypothesis testing can be employed. Knowledge of football is not necess ..."
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is not necessary; however, basic knowledge regarding how points are scored might prove beneficial.

Efficient Capital Market: II” ,

by Eugene F Fama , Fischer Black , David Booth , Michael Bradley , Michael Brennan , Stephen Buser , John Campbell , Nai-Fu Chen , John Cochrane , George Constantinides , Wayne Ferson , Kenneth French , Campbell Harvey , Richard Ippolito , Michael Jensen , Gautam Kaul , Josef Lakonishok , Bill Mcdonald , Robert Merton , Mark Mitchell , Sam Peltzman , Marc Reinganum , Jay Ritter , Harry Roberts , Richard Roll , G William Schwert , H Nejat Seyhun , Jay Shanken , Robert Shiller , Andrei Shleifer , Rex Sinquefield , Rene Stulz , Richard Thaler , Robert Vishny , Jerold Warner - Journal of Finance, No , 1991
"... SEQUELS ARE RARELY AS good as the originals, so I approach this review of the market efflciency literature with trepidation. The task is thornier than it was 20 years ago, when work on efficiency was rather new. The literature is now so large that a full review is impossible, and is not attempted h ..."
Abstract - Cited by 337 (0 self) - Add to MetaCart
to the point where the marginal benefits of acting on information (the profits to be made) do not exceed the marginal costs (Jensen (1978)). Since there are surely positive information and trading costs, the extreme version of the market efficiency hypothesis is surely false. Its advantage, however
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