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Results 1 - 10
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13,441
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
, 2002
"... There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling efficiency between the two fluorescent dyes). The term normalization refers to the process of removing such variation. A constant adjustment is ..."
Abstract
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Cited by 718 (9 self)
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is often used to force the distribution of the intensity log ratios to have a median of zero for each slide. However, such global normalization approaches are not adequate in situations where dye biases can depend on spot overall intensity and/or spatial location within the array. This article proposes
ReVirt: Enabling Intrusion Analysis through Virtual-Machine Logging and Replay
- In Proceedings of the 2002 Symposium on Operating Systems Design and Implementation (OSDI
, 2002
"... Rights to individual papers remain with the author or the author's employer. Permission is granted for noncommercial reproduction of the work for educational or research purposes. This copyright notice must be included in the reproduced paper. USENIX acknowledges all trademarks herein. Current ..."
Abstract
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Cited by 469 (26 self)
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for interactive use and CPU-bound workloads, and 13-58 % for kernel-intensive workloads. Logging adds 0-8 % overhead, and logging
A Threshold of ln n for Approximating Set Cover
- JOURNAL OF THE ACM
, 1998
"... Given a collection F of subsets of S = f1; : : : ; ng, set cover is the problem of selecting as few as possible subsets from F such that their union covers S, and max k-cover is the problem of selecting k subsets from F such that their union has maximum cardinality. Both these problems are NP-har ..."
Abstract
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Cited by 776 (5 self)
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o(1)) ln n), and previous results of Lund and Yannakakis, that showed hardness of approximation within a ratio of (log 2 n)=2 ' 0:72 lnn. For max k-cover we show an approximation threshold of (1 \Gamma 1=e) (up to low order terms), under the assumption that P != NP .
Relations between the statistics of natural images and the response properties of cortical cells
- J. Opt. Soc. Am. A
, 1987
"... The relative efficiency of any particular image-coding scheme should be defined only in relation to the class of images that the code is likely to encounter. To understand the representation of images by the mammalian visual system, it might therefore be useful to consider the statistics of images f ..."
Abstract
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Cited by 831 (18 self)
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cells are well suited for coding the information in such images if the goal of the code is to convert higher-order redundancy (e.g., correlation between the intensities of neighboring pixels) into first-order redundancy (i.e., the response distribution of the coefficients). Such coding produces a
Exploration, normalization, and summaries of high density oligonucleotide array probe level data.
- Biostatistics,
, 2003
"... SUMMARY In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip R system with the objective of improving upon currently used measures of gene expression. Our analyses make use of three data sets: a small experimental study consisting of f ..."
Abstract
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Cited by 854 (33 self)
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intensities. We then examine the behavior of the P M and M M using spike-in data and assess three commonly used summary measures: Affymetrix's (i) average difference (AvDiff) and (ii) MAS 5.0 signal, and (iii) the Li and Wong multiplicative model-based expression index (MBEI). The exploratory data
Brain magnetic resonance imaging with contrast dependent on blood oxygenation.
- Proc. Natl. Acad. Sci. USA
, 1990
"... ABSTRACT Paramagnetic deoxyhemoglobin in venous blood is a naturally occurring contrast agent for magnetic resonance imaging (MRI). By accentuating the effects of this agent through the use of gradient-echo techniques in high fields, we demonstrate in vivo images of brain microvasculature with imag ..."
Abstract
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Cited by 648 (1 self)
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dispersion of water proton signals is produced at the echo time. This dispersion reduces the signal intensity and the voxel appears dark in the image. These intensity losses, which at high magnetic fields (-4 T) extend significantly beyond the boundary of the blood vessel, are the source of BOLD contrast
On-line selection of discriminative tracking features
, 2003
"... This paper presents an on-line feature selection mechanism for evaluating multiple features while tracking and adjusting the set of features used to improve tracking performance. Our hypothesis is that the features that best discriminate between object and background are also best for track-ing the ..."
Abstract
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Cited by 356 (5 self)
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the object. Given a set of seed features, we compute log likelihood ratios of class conditional sample densities from object and background to form a new set of candidate features tailored to the local object/background discrimination task. The two-class variance ratio is used to rank these new features
On the capacity of MIMO broadcast channel with partial side information
- IEEE TRANS. INFORM. THEORY
, 2005
"... In multiple-antenna broadcast channels, unlike point-to-point multiple-antenna channels, the multiuser capacity depends heavily on whether the transmitter knows the channel coefficients to each user. For instance, in a Gaussian broadcast channel with transmit antennas and single-antenna users, the ..."
Abstract
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Cited by 349 (9 self)
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, the sum rate capacity scales like log log for large if perfect channel state information (CSI) is available at the transmitter, yet only logarithmically with if it is not. In systems with large, obtaining full CSI from all users may not be feasible. Since lack of CSI does not lead to multiuser gains
Unified segmentation
, 2005
"... A probabilistic framework is presented that enables image registration, tissue classification, and bias correction to be combined within the same generative model. A derivation of a log-likelihood objective function for the unified model is provided. The model is based on a mixture of Gaussians and ..."
Abstract
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Cited by 324 (12 self)
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A probabilistic framework is presented that enables image registration, tissue classification, and bias correction to be combined within the same generative model. A derivation of a log-likelihood objective function for the unified model is provided. The model is based on a mixture of Gaussians
Quest: a bayesian adaptive psychometric method
- PERCEPT PSYCHOPHYS
, 1983
"... An adaptive psychometric procedure that places each trial at the current most probable Baye& ian estimate of threshold is described. The procedure takes advantage of the common finding that the human psychometric function is invariant in form when expressed as a function of log intensity. The pr ..."
Abstract
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Cited by 321 (25 self)
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An adaptive psychometric procedure that places each trial at the current most probable Baye& ian estimate of threshold is described. The procedure takes advantage of the common finding that the human psychometric function is invariant in form when expressed as a function of log intensity
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