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Probabilistic Latent Semantic Indexing

by Thomas Hofmann , 1999
"... Probabilistic Latent Semantic Indexing is a novel approach to automated document indexing which is based on a statistical latent class model for factor analysis of count data. Fitted from a training corpus of text documents by a generalization of the Expectation Maximization algorithm, the utilized ..."
Abstract - Cited by 1225 (10 self) - Add to MetaCart
Probabilistic Latent Semantic Indexing is a novel approach to automated document indexing which is based on a statistical latent class model for factor analysis of count data. Fitted from a training corpus of text documents by a generalization of the Expectation Maximization algorithm, the utilized

Linear models and empirical bayes methods for assessing differential expression in microarray experiments.

by Gordon K Smyth , Gordon K Smyth - Stat. Appl. Genet. Mol. Biol. , 2004
"... Abstract The problem of identifying differentially expressed genes in designed microarray experiments is considered. Lonnstedt and Speed (2002) derived an expression for the posterior odds of differential expression in a replicated two-color experiment using a simple hierarchical parametric model. ..."
Abstract - Cited by 1321 (24 self) - Add to MetaCart
Abstract The problem of identifying differentially expressed genes in designed microarray experiments is considered. Lonnstedt and Speed (2002) derived an expression for the posterior odds of differential expression in a replicated two-color experiment using a simple hierarchical parametric model

Surface deformation due to shear and tensile faults in a half-space

by Yoshimitsu Okada , 1985
"... A complete set of closed analytical expressions is presented in a unified manner for the internal displacements and strains due to shear and tensile faults in a half-space for both point and finite rectangular sources. These expressions are particularly compact and systematically composed of terms r ..."
Abstract - Cited by 727 (1 self) - Add to MetaCart
representing deformations in an infinite medium, a term related to surface deformation and that is multiplied by the depth of observation point. Several practical suggestions to avoid mathematical singularities and computational instabilities are also presented. The expressions derived here represent power-ful

Model-Based Analysis of Oligonucleotide Arrays: Model Validation, Design Issues and Standard Error Application

by Cheng Li, Wing Hung Wong , 2001
"... Background: A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe pair and calculates model-based expression indexes (MBEI). MBEI has standard error attached to it as a measure of ..."
Abstract - Cited by 775 (28 self) - Add to MetaCart
's presence in many arrays of an array set allows the probe-sensitivity index to be estimated accurately. We extended the model to obtain expression values for PM-only arrays, and found that the 20-probe PM-only model is comparable to the 10-probe PM/MM difference model, in terms of the expression

Space-time block codes from orthogonal designs

by Vahid Tarokh, Hamid Jafarkhani, A. R. Calderbank - IEEE Trans. Inform. Theory , 1999
"... Abstract — We introduce space–time block coding, a new paradigm for communication over Rayleigh fading channels using multiple transmit antennas. Data is encoded using a space–time block code and the encoded data is split into � streams which are simultaneously transmitted using � transmit antennas. ..."
Abstract - Cited by 1524 (42 self) - Add to MetaCart
decoding algorithm. The classical mathematical framework of orthogonal designs is applied to construct space–time block codes. It is shown that space–time block codes constructed in this way only exist for few sporadic values of �. Subsequently, a generalization of orthogonal designs is shown to provide

Modeling and simulation of genetic regulatory systems: A literature review

by Hidde De Jong - JOURNAL OF COMPUTATIONAL BIOLOGY , 2002
"... In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between ..."
Abstract - Cited by 738 (14 self) - Add to MetaCart
for the modeling and simulation of genetic regulatory networks will be indispensable. This paper reviews formalisms that have been employed in mathematical biology and bioinformatics to describe genetic regulatory systems, in particular directed graphs, Bayesian networks, Boolean networks and their generalizations

Graphical models, exponential families, and variational inference

by Martin J. Wainwright, Michael I. Jordan , 2008
"... The formalism of probabilistic graphical models provides a unifying framework for capturing complex dependencies among random variables, and building large-scale multivariate statistical models. Graphical models have become a focus of research in many statistical, computational and mathematical fiel ..."
Abstract - Cited by 819 (28 self) - Add to MetaCart
all be understood in terms of exact or approximate forms of these variational representations. The variational approach provides a complementary alternative to Markov chain Monte Carlo as a general source of approximation methods for inference in large-scale statistical models.

Exploration, normalization, and summaries of high density oligonucleotide array probe level data.

by Rafael A Irizarry , Bridget Hobbs , Francois Collin , Yasmin D Beazer-Barclay , Kristen J Antonellis , Uwe Scherf , Terence P Speed - Biostatistics, , 2003
"... SUMMARY In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip R system with the objective of improving upon currently used measures of gene expression. Our analyses make use of three data sets: a small experimental study consisting of f ..."
Abstract - Cited by 854 (33 self) - Add to MetaCart
intensities. We then examine the behavior of the P M and M M using spike-in data and assess three commonly used summary measures: Affymetrix's (i) average difference (AvDiff) and (ii) MAS 5.0 signal, and (iii) the Li and Wong multiplicative model-based expression index (MBEI). The exploratory data

Motivation through the Design of Work: Test of a Theory. Organizational Behavior and Human Performance,

by ] Richard Hackman , Grec R Oldham , 1976
"... A model is proposed that specifies the conditions under which individuals will become internally motivated to perform effectively on their jobs. The model focuses on the interaction among three classes of variables: (a) the psychological states of employees that must be present for internally motiv ..."
Abstract - Cited by 622 (2 self) - Add to MetaCart
was unrelated to the Index. The investigators concluded that reactions to jobs high on the RTA Index were moderated by differences in the cultural backgrounds of employees. Subsequent research by A study by Results of the study generally supported the hypothesis that employees who work on jobs high

Service Disciplines for Guaranteed Performance Service in Packet-Switching Networks

by Hui Zhang - Proceedings of the IEEE , 1995
"... While today’s computer networks support only best-effort service, future packet-switching integrated-services networks will have to support real-time communication services that allow clients to transport information with performance guarantees expressed in terms of delay, delay jitter, throughput, ..."
Abstract - Cited by 609 (4 self) - Add to MetaCart
While today’s computer networks support only best-effort service, future packet-switching integrated-services networks will have to support real-time communication services that allow clients to transport information with performance guarantees expressed in terms of delay, delay jitter, throughput
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