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approval from the US Food and Drug Administration in
"... an orally available, reversible human epidermal growth fac-tor receptor (EGFR) tyrosine kinase inhibitor[1, 2]. It received ..."
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an orally available, reversible human epidermal growth fac-tor receptor (EGFR) tyrosine kinase inhibitor[1, 2]. It received
Conflict of interest notification: none
, 2010
"... moral hemorrhage, pituitary adeno-ma, vascular endothelial growth fac-tor. Acknowledgments: This work was supported by the research fund of ..."
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moral hemorrhage, pituitary adeno-ma, vascular endothelial growth fac-tor. Acknowledgments: This work was supported by the research fund of
EXPERIMENTAL PROCEDURE
, 1955
"... ST U D I E S on unidentified growth fac-tors for poultry have been comprehen- ..."
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ST U D I E S on unidentified growth fac-tors for poultry have been comprehen-
Original Article Irbesartan Treatment Reduces Biomarkers of Inflammatory Activity in Patients With Type 2 Diabetes
"... The impact of irbesartan treatment on biomarkers of low-grade inflammation, endothelial dysfunction, growth fac-tors, and advanced glycation end products (AGEs) during the Irbesartan in Patients with Type 2 Diabetes and Mi-croalbuminuria (IRMA 2) study was evaluated. IRMA 2 was a 2-year multicenter, ..."
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The impact of irbesartan treatment on biomarkers of low-grade inflammation, endothelial dysfunction, growth fac-tors, and advanced glycation end products (AGEs) during the Irbesartan in Patients with Type 2 Diabetes and Mi-croalbuminuria (IRMA 2) study was evaluated. IRMA 2 was a 2-year multicenter
Knockdown of VEGFR2 inhibitsproliferation and induces apoptosis in hemangioma-derived endothelial cells
"... Angiogenesis is a process of development and growth of new capillary blood vessels from pre-existing vessels. Angiogenic growth fac-tors play important roles in the development and maintenance of some malignancies, of which vascular endothelial growth factor (VEGF)/VEGFR2 interactions are involved i ..."
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Angiogenesis is a process of development and growth of new capillary blood vessels from pre-existing vessels. Angiogenic growth fac-tors play important roles in the development and maintenance of some malignancies, of which vascular endothelial growth factor (VEGF)/VEGFR2 interactions are involved
Author's View www.landesbioscience.com oncoimmunology e28399-1
, 2014
"... Author's View The process of tumor neo-vascular-ization (angiogenesis) is considered a major target in the treatment of cancer, as are the growth factors that drive the proliferation of constituent vasculature endothelial cells. The general aim of this therapeutic approach is to asphyxiate tumo ..."
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tumors by depriving them of oxygen and nutrients obtained from the blood. Anti-angiogenesis therapies typically comprise inhibitors of these angiogenic growth fac-tors or their cognate receptors and such agents have been approved for the treat-ment of colon, breast, lung, kidney, brain,
chronic anti-TGF-beta antibody therapy in Dahl S rats. Am J Physiol
, 1115
"... extracellular matrix protein synthesis through induction of trans-forming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest 1994; 93: 2431–2437 35. Okada H, Kikuta T, Kobayashi T et al. Connective tissue growth fac-tor expressed in tubular epithelium plays a pivotal role ..."
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extracellular matrix protein synthesis through induction of trans-forming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest 1994; 93: 2431–2437 35. Okada H, Kikuta T, Kobayashi T et al. Connective tissue growth fac-tor expressed in tubular epithelium plays a pivotal
unknown title
"... Multiple myeloma (MM) is a plasmacell malignancy character-ized by the tight relationship with the bone marrow (BM) microen-vironment that has a pivotal role in the regulation of myeloma cell growth and survival through the production of several growth fac-tors and the increase of BM angiogenesis. B ..."
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Multiple myeloma (MM) is a plasmacell malignancy character-ized by the tight relationship with the bone marrow (BM) microen-vironment that has a pivotal role in the regulation of myeloma cell growth and survival through the production of several growth fac-tors and the increase of BM angiogenesis
Asahara T. Effects of statins on angiogenesis and vasculogenesis. Rev Esp Cardiol. 2002; 55: 838–844
- PMID: 12199980 Angiogenesis in Hypertension PLOS ONE | DOI:10.1371/journal.pone.0126190 May 7, 2015 17 / 17
"... Statins promote the proliferation, migration, and survi-val of endothelial cells and bone marrow-derived endo-thelial progenitor cells (angioblasts) by stimulating the se-rine/threonine protein kinase Akt (also known as protein kinase B) pathway. Like vascular endothelial growth fac-tor (VEGF), the ..."
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Statins promote the proliferation, migration, and survi-val of endothelial cells and bone marrow-derived endo-thelial progenitor cells (angioblasts) by stimulating the se-rine/threonine protein kinase Akt (also known as protein kinase B) pathway. Like vascular endothelial growth fac-tor (VEGF
General Background Issues Concerning Cancer Risk Assessment
"... In this review, selected examples of recent research developments concerning insulin-like growth fac-tors (IGFs) and insulin in the context of cancer risk assessment and prevention will be discussed. We reviewed background information related to IGF physiology at the cellular and whole-organ-ism lev ..."
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In this review, selected examples of recent research developments concerning insulin-like growth fac-tors (IGFs) and insulin in the context of cancer risk assessment and prevention will be discussed. We reviewed background information related to IGF physiology at the cellular and whole
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