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Missing value estimation methods for DNA microarrays
, 2001
"... Motivation: Gene expression microarray experiments can generate data sets with multiple missing expression values. Unfortunately, many algorithms for gene expression analysis require a complete matrix of gene array values as input. For example, methods such as hierarchical clustering and K-means clu ..."
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Cited by 477 (24 self)
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Motivation: Gene expression microarray experiments can generate data sets with multiple missing expression values. Unfortunately, many algorithms for gene expression analysis require a complete matrix of gene array values as input. For example, methods such as hierarchical clustering and K
Model-Based Analysis of Oligonucleotide Arrays: Model Validation, Design Issues and Standard Error Application
, 2001
"... Background: A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe pair and calculates model-based expression indexes (MBEI). MBEI has standard error attached to it as a measure of ..."
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Cited by 775 (28 self)
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's presence in many arrays of an array set allows the probe-sensitivity index to be estimated accurately. We extended the model to obtain expression values for PM-only arrays, and found that the 20-probe PM-only model is comparable to the 10-probe PM/MM difference model, in terms of the expression
A Bayesian Framework for the Analysis of Microarray Expression Data: Regularized t-Test and Statistical Inferences of Gene Changes
- Bioinformatics
, 2001
"... Motivation: DNA microarrays are now capable of providing genome-wide patterns of gene expression across many different conditions. The first level of analysis of these patterns requires determining whether observed differences in expression are significant or not. Current methods are unsatisfactory ..."
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Cited by 491 (6 self)
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due to the lack of a systematic framework that can accommodate noise, variability, and low replication often typical of microarray data. Results: We develop a Bayesian probabilistic framework for microarray data analysis. At the simplest level, we model log-expression values by independent normal
Symbolic Model Checking for Real-time Systems
- INFORMATION AND COMPUTATION
, 1992
"... We describe finite-state programs over real-numbered time in a guarded-command language with real-valued clocks or, equivalently, as finite automata with real-valued clocks. Model checking answers the question which states of a real-time program satisfy a branching-time specification (given in an ..."
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Cited by 578 (50 self)
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We describe finite-state programs over real-numbered time in a guarded-command language with real-valued clocks or, equivalently, as finite automata with real-valued clocks. Model checking answers the question which states of a real-time program satisfy a branching-time specification (given
Learning logical definitions from relations
- MACHINE LEARNING
, 1990
"... This paper describes FOIL, a system that learns Horn clauses from data expressed as relations. FOIL is based on ideas that have proved effective in attribute-value learning systems, but extends them to a first-order formalism. This new system has been applied successfully to several tasks taken fro ..."
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Cited by 935 (8 self)
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This paper describes FOIL, a system that learns Horn clauses from data expressed as relations. FOIL is based on ideas that have proved effective in attribute-value learning systems, but extends them to a first-order formalism. This new system has been applied successfully to several tasks taken
Exploration, normalization, and summaries of high density oligonucleotide array probe level data.
- Biostatistics,
, 2003
"... SUMMARY In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix GeneChip R system with the objective of improving upon currently used measures of gene expression. Our analyses make use of three data sets: a small experimental study consisting of f ..."
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Cited by 854 (33 self)
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analyses of the probe level data motivate a new summary measure that is a robust multiarray average (RMA) of background-adjusted, normalized, and log-transformed P M values. We evaluate the four expression summary measures using the dilution study data, assessing their behavior in terms of bias, variance
Implementing data cubes efficiently
- In SIGMOD
, 1996
"... Decision support applications involve complex queries on very large databases. Since response times should be small, query optimization is critical. Users typically view the data as multidimensional data cubes. Each cell of the data cube is a view consisting of an aggregation of interest, like total ..."
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Cited by 548 (1 self)
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total sales. The values of many of these cells are dependent on the values of other cells in the data cube..A common and powerful query optimization technique is to materialize some or all of these cells rather than compute them from raw data each time. Commercial systems differ mainly in their approach
Metaphors We Live By
, 1980
"... 1. Make a list of some of the metaphors discussed by Lakoff and Johnson. Try inserting new words that convey a different meaning. For example, consider the expression, “I’d like to share some time with you ” rather than “spend some time with you.” 2. Make a list of “language asymmetries ” (see Part ..."
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Cited by 3387 (7 self)
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1. Make a list of some of the metaphors discussed by Lakoff and Johnson. Try inserting new words that convey a different meaning. For example, consider the expression, “I’d like to share some time with you ” rather than “spend some time with you.” 2. Make a list of “language asymmetries ” (see Part
The design and implementation of an intentional naming system
- 17TH ACM SYMPOSIUM ON OPERATING SYSTEMS PRINCIPLES (SOSP '99) PUBLISHED AS OPERATING SYSTEMS REVIEW, 34(5):186--201, DEC. 1999
, 1999
"... This paper presents the design and implementation of the Intentional Naming System (INS), a resource discovery and service location system for dynamic and mobile networks of devices and computers. Such environments require a naming system that is (i) expressive, to describe and make requests based o ..."
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Cited by 518 (14 self)
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This paper presents the design and implementation of the Intentional Naming System (INS), a resource discovery and service location system for dynamic and mobile networks of devices and computers. Such environments require a naming system that is (i) expressive, to describe and make requests based
Culture and the self: Implications for cognition, emotion, and motivation
- Psychological Review
, 1991
"... People in different cultures have strikingly different construals of the self, of others, and of the interdependence of the 2. These construals can influence, and in many cases determine, the very nature of individual experience, including cognition, emotion, and motivation. Many Asian cultures have ..."
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Cited by 1832 (35 self)
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have distinct conceptions of individuality that insist on the fundamental relatedness of individuals to each other. The emphasis is on attending to others, fitting in, and harmonious interdependence with them. American culture neither assumes nor values such an overt connectedness among individuals
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