Results 1 - 10 of 12,548

Refining motif finders with E-value calculations

by Niranjan Nagarajan, Patrick Ng, Uri Keich
"... Motif finders are an important tool for searching for regulatory elements in DNA. Popular existing programs optimize the entropy score to efficiently search for motifs. While E-values are commonly used for assigning significance to the optimal reported motifs they are not directly optimized for. Thi ..."
Abstract - Cited by 4 (2 self) - Add to MetaCart
Motif finders are an important tool for searching for regulatory elements in DNA. Popular existing programs optimize the entropy score to efficiently search for motifs. While E-values are commonly used for assigning significance to the optimal reported motifs they are not directly optimized for

Evaluating the Accuracy of Sampling-Based Approaches to the Calculation of Posterior Moments

by John Geweke - IN BAYESIAN STATISTICS , 1992
"... Data augmentation and Gibbs sampling are two closely related, sampling-based approaches to the calculation of posterior moments. The fact that each produces a sample whose constituents are neither independent nor identically distributed complicates the assessment of convergence and numerical accurac ..."
Abstract - Cited by 604 (12 self) - Add to MetaCart
accuracy of the approximations to the expected value of functions of interest under the posterior. In this paper methods from spectral analysis are used to evaluate numerical accuracy formally and construct diagnostics for convergence. These methods are illustrated in the normal linear model

Do Better Schools Matter? Parental Valuation of Elementary Education

by Sandra E. Black - QUARTERLY JOURNAL OF ECONOMICS , 1999
"... The evaluation of numerous school reforms requires an understanding of the value of better schools. Given the difficulty of calculating the relationship between school quality and student outcomes, I turn to another method and use house prices to infer the value parents place on school quality. I lo ..."
Abstract - Cited by 500 (3 self) - Add to MetaCart
The evaluation of numerous school reforms requires an understanding of the value of better schools. Given the difficulty of calculating the relationship between school quality and student outcomes, I turn to another method and use house prices to infer the value parents place on school quality. I

Activity recognition from user-annotated acceleration data

by Ling Bao, Stephen S. Intille , 2004
"... In this work, algorithms are developed and evaluated to detect physical activities from data acquired using five small biaxial accelerometers worn simultaneously on different parts of the body. Acceleration data was collected from 20 subjects without researcher supervision or observation. Subjects ..."
Abstract - Cited by 515 (7 self) - Add to MetaCart
In this work, algorithms are developed and evaluated to detect physical activities from data acquired using five small biaxial accelerometers worn simultaneously on different parts of the body. Acceleration data was collected from 20 subjects without researcher supervision or observation

Loopy belief propagation for approximate inference: An empirical study. In:

by Kevin P Murphy , Yair Weiss , Michael I Jordan - Proceedings of Uncertainty in AI, , 1999
"... Abstract Recently, researchers have demonstrated that "loopy belief propagation" -the use of Pearl's polytree algorithm in a Bayesian network with loops -can perform well in the context of error-correcting codes. The most dramatic instance of this is the near Shannon-limit performanc ..."
Abstract - Cited by 676 (15 self) - Add to MetaCart
. Introduction The task of calculating posterior marginals on nodes in an arbitrary Bayesian network is known to be NP hard In this paper we investigate the approximation performance of "loopy belief propagation". This refers to using the well-known Pearl polytree algorithm [12] on a Bayesian network

Effective Energy Function for Proteins in Solution

by Themis Lazaridis, Martin Karplus , 1999
"... A Gaussian solvent-exclusion model for the solvation free energy is developed. It is based on theoretical considerations and parametrized with experimental data. When combined with the CHARMM 19 polar hydrogen energy function, it provides an effective energy function (EEF1) for proteins in solution. ..."
Abstract - Cited by 259 (16 self) - Add to MetaCart
. The solvation model assumes that the solvation free energy of a protein molecule is a sum of group contributions, which are determined from values for small model compounds. For charged groups, the self-energy contribution is accounted for primarily by the exclusion model. Ionic side-chains are neutralized

Perceived organizational support and employee diligence, commitment, and innovation

by Robert Eisenberger, Peter Fasolo, Valerie Davis-lamastro - Journal of Applied Psychology , 1990
"... Two studies report a positive relationship ofemployees ' perception ofbeing valued and cared about by the organization with (a) conscientiousness in carrying out conventional job responsibilities, (b) expressed affective and calculative involvements in the organization, and (e) innovation on be ..."
Abstract - Cited by 238 (7 self) - Add to MetaCart
Two studies report a positive relationship ofemployees ' perception ofbeing valued and cared about by the organization with (a) conscientiousness in carrying out conventional job responsibilities, (b) expressed affective and calculative involvements in the organization, and (e) innovation

Bayesian inference on phylogeny and its impact on evolutionary biology.

by John P Huelsenbeck , Fredrik Ronquist , Rasmus Nielsen , Jonathan P Bollback - Science , 2001
"... 1 As a discipline, phylogenetics is becoming transformed by a flood of molecular data. These data allow broad questions to be asked about the history of life, but also present difficult statistical and computational problems. Bayesian inference of phylogeny brings a new perspective to a number of o ..."
Abstract - Cited by 235 (10 self) - Add to MetaCart
of that tree (10). Although MCMC has made analysis of many complex models possible, it is not a panacea, as chains can fail to converge to the stationary distribution for a number of reasons (e.g., a poor Problem Bayesian approach Ref. Inferring phylogeny Find tree with maximum posterior probability; evaluate

COMPASS: a tool for comparison of multiple protein alignments with assessment of statistical significance

by Ruslan Sadreyev, Nick Grishin, Howard Hughes Medical - J. Mol. Biol , 2003
"... We present a novel method for the comparison of multiple protein align-ments with assessment of statistical significance (COMPASS). The method derives numerical profiles from alignments, constructs optimal local profile–profile alignments and analytically estimates E-values for the detected similari ..."
Abstract - Cited by 125 (33 self) - Add to MetaCart
similarities. The scoring system and E-value calculation are based on a generalization of the PSI-BLAST approach to profile–sequence comparison, which is adapted for the profile–profile case. Tested along with existing methods for profile–sequence (PSI-BLAST) and profile– profile (prof_sim) comparison, COMPASS

to Calculation

by Mike Cooley, Mike Cooley Engineer
"... frequently come between the professional and the primary task as the real world of touch, shape, size, form (and smell) is replaced by an image on a screen or a stream of data or calculation outputs. This can lead to high levels of abstraction where the ability to judge is diminished. I have describ ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
frequently come between the professional and the primary task as the real world of touch, shape, size, form (and smell) is replaced by an image on a screen or a stream of data or calculation outputs. This can lead to high levels of abstraction where the ability to judge is diminished. I have
Results 1 - 10 of 12,548