Andrew Warner for generously sharing their data with us. We are particularly grateful to Ben-David, Frankel, Romer, Sachs, Warner and Romain Wacziarg for helpful e-mail exchanges. We have benefited greatly from discussions in seminars at the University of California at Berkeley,

A new approach to the problem of multimodality medical image registration is proposed, using a basic concept from information theory, mutual information (MI), or relative entropy, as a new matching criterion. The method presented in this paper applies MI to measure the statistical dependence or information redundancy between the image intensities of corresponding voxels in both images, which is assumed to be maximal if the images are geometrically aligned. Maximization of MI is a very general and powerful criterion, because no assumptions are made regarding the nature of this dependence and no limiting constraints are imposed on the image content of the modalities involved. The accuracy of the MI criterion is validated for rigid body registration of computed tomography (CT), magnetic resonance (MR), and photon emission tomography (PET) images by comparison with the stereotactic registration solution, while robustness is evaluated with respect to implementation issues, such as interpolation and optimization, and image content, including partial overlap and image degradation. Our results demonstrate that subvoxel accuracy with respect to the stereotactic reference solution can be achieved completely automatically and without any prior segmentation, feature extraction, or other preprocessing steps which makes this method very well suited for clinical applications.

We describe a system for representing moving images with sets of overlapping layers. Each layer contains an intensity map that defines the additive values of each pixel, along with an alpha map that serves as a mask indicating the transparency. The layers are ordered in depth and they occlude each other in accord with the rules of compositing. Velocity maps define how the layers are to be warped over time. The layered representation is more flexible than standard image transforms and can capture many important properties of natural image sequences. We describe some methods for decomposing image sequences into layers using motion analysis, and we discuss how the representation may be used for image coding and other applications.

Abstract Several common systems satisfy some but not all of the VR This paper describes the CAVE (CAVE Automatic Virtual Environment) virtual reality/scientific visualization system in detail and demonstrates that projection technology applied to virtual-reality goals achieves a system that matches the quality of workstation screens in terms of resolution, color, and flicker-free stereo. In addition, this format helps reduce the effect of common tracking and system latency errors. The off-axis perspective projection techniques we use are shown to be simple and straightforward. Our techniques for doing multi-screen stereo vision are enumerated, and design barriers, past and current, are described. Advantages and disadvantages of the projection paradigm are discussed, with an analysis of the effect of tracking noise and delay on the user. Successive refinement, a necessary tool for scientific visualization, is developed in the virtual reality context. The use of the CAVE as a one-to-many presentation

Stable local feature detection and representation is a fundamental component of many image registration and object recognition algorithms. Mikolajczyk and Schmid [14] recently evaluated a variety of approaches and identified the SIFT [11] algorithm as being the most resistant to common image deformations. This paper examines (and improves upon) the local image descriptor used by SIFT. Like SIFT, our descriptors encode the salient aspects of the image gradient in the feature point's neighborhood; however, instead of using SIFT's smoothed weighted histograms, we apply Principal Components Analysis (PCA) to the normalized gradient patch. Our experiments demonstrate that the PCAbased local descriptors are more distinctive, more robust to image deformations, and more compact than the standard SIFT representation. We also present results showing that using these descriptors in an image retrieval application results in increased accuracy and faster matching.

This paper aims to present a review of recent as well as classic image registration methods. Image registration is the process of overlaying images (two or more) of the same scene taken at different times, from different viewpoints, and/or by different sensors. The registration geometrically align two images (the reference and sensed images). The reviewed approaches are classified according to their nature (areabased and feature-based) and according to four basic steps of image registration procedure: feature detection, feature matching, mapping function design, and image transformation and resampling. Main contributions, advantages, and drawbacks of the methods are mentioned in the paper. Problematic issues of image registration and outlook for the future research are discussed too. The major goal of the paper is to provide a comprehensive reference source for the researchers involved in image registration, regardless of particular application areas.

In this paper, we develop methods to rapidly remove rough features from irregularly triangulated data intended to portray a smooth surface. The main task is to remove undesirable noise and uneven edges while retaining desirable geometric features. The problem arises mainly when creating high-fidelity computer graphics objects using imperfectly-measured data from the real world. Our approach contains three novel features: an implicit integration method to achieve efficiency, stability, and large time-steps; a scale-dependent Laplacian operator to improve the diffusion process; and finally, a robust curvature flow operator that achieves a smoothing of the shape itself, distinct from any parameterization. Additional features of the algorithm include automatic exact volume preservation, and hard and soft constraints on the positions of the points in the mesh. We compare our method to previous operators and related algorithms, and prove that our curvature and Laplacian operators have several mathematically-desirable qualities that improve the appearance of the resulting surface. In consequence, the user can easily select the appropriate operator according to the desired type of fairing. Finally, we provide a series of examples to graphically and numerically demonstrate the quality of our results.

The intuitive background for measures of structural centrality in social networks is reviewed aPzd existing measures are evaluated in terms of their consistency with intuitions and their interpretability. Three distinct intuitive conceptions of centrality are uncovered and existing measures are refined to embody these conceptions. Three measures are developed for each concept, one absolute and one relative measure of the ~entra~~t~ ~ of ~os~tio~ls in a network, and one relenting the degree of centralization of the entire network. The implications of these measures for the experimental study of small groups is examined. The problem of centrality The idea of centrality as applied to human communication was introduced by Bavelas in 1948. He was specifically concerned with communication in small groups and he hypothesized a relationship between structural centrality and influence in group processes.

We present a novel approach to measuring similarity between shapes and exploit it for object recognition. In our framework, the measurement of similarity is preceded by (1) solv- ing for correspondences between points on the two shapes, (2) using the correspondences to estimate an aligning transform. In order to solve the correspondence problem, we attach a descriptor, the shape context, to each point. The shape context at a reference point captures the distribution of the remaining points relative to it, thus offering a globally discriminative characterization. Corresponding points on two similar shapes will have similar shape con- texts, enabling us to solve for correspondences as an optimal assignment problem. Given the point correspondences, we estimate the transformation that best aligns the two shapes; reg- ularized thin plate splines provide a flexible class of transformation maps for this purpose. The dissimilarity between the two shapes is computed as a sum of matching errors between corresponding points, together with a term measuring the magnitude of the aligning trans- form. We treat recognition in a nearest-neighbor classification framework as the problem of finding the stored prototype shape that is maximally similar to that in the image. Results are presented for silhouettes, trademarks, handwritten digits and the COIL dataset.

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