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Fundamental Design Issues for the Future Internet

by Scott Shenker - IEEE JOURNAL ON SELECTED AREAS IN COMMUNICATIONS , 1995
"... The Internet has been a startling and dramatic success. However, multimedia applications, with their novel traffic characteristics and service requirements, pose an interesting challenge to the technical foundations of the Internet. In this paper we address some of the fundamental architectural d ..."
Abstract - Cited by 471 (3 self) - Add to MetaCart
design issues facing the future Internet. In particular, we discuss whether the Internet should adopt a new service model, how this service model should be invoked, and whether this service model should include admission control. These architectural issues are discussed in a nonrigorous manner

Model-Based Analysis of Oligonucleotide Arrays: Model Validation, Design Issues and Standard Error Application

by Cheng Li, Wing Hung Wong , 2001
"... Background: A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe pair and calculates model-based expression indexes (MBEI). MBEI has standard error attached to it as a measure of ..."
Abstract - Cited by 775 (28 self) - Add to MetaCart
Background: A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe pair and calculates model-based expression indexes (MBEI). MBEI has standard error attached to it as a measure of accuracy. Here we investigate the stability of the probe-sensitivity index across different tissue types, the reproducibility of results in replicate experiments, and the use of MBEI in perfect match (PM)-only arrays. Results: Probe-sensitivity indexes are stable across tissue types. The target gene's presence in many arrays of an array set allows the probe-sensitivity index to be estimated accurately. We extended the model to obtain expression values for PM-only arrays, and found that the 20-probe PM-only model is comparable to the 10-probe PM/MM difference model, in terms of the expression correlations with the original 20-probe PM/MM difference model. MBEI method is able to extend the reliable detection limit of expression to a lower mRNA concentration. The standard errors of MBEI can be used to construct confidence intervals of fold changes, and the lower confidence bound of fold change is a better ranking statistic for filtering genes. We can assign reliability indexes for genes in a specific cluster of interest in hierarchical clustering by resampling clustering trees. A software dChip implementing many of these analysis methods is made available. Conclusions: The model-based approach reduces the variability of low expression estimates, and provides a natural method of calculating expression values for PM-only arrays. The standard errors attached to expression values can be used to assess the reliability of downstream analysis. Published: X Month 2001 Genome Biology...

Design and Implementation or the Sun Network Filesystem

by Russel Sandberg, David Goldberg, Steve Kleiman, Dan Walsh, Bob Lyon , 1985
"... this paper we discuss the design and implementation of the/'fiesystem interface in the kernel and the NF$ virtual/'fiesystem. We describe some interesting design issues and how they were resolved, and point out some of the shortcomings of the current implementation. We conclude with some i ..."
Abstract - Cited by 502 (0 self) - Add to MetaCart
this paper we discuss the design and implementation of the/'fiesystem interface in the kernel and the NF$ virtual/'fiesystem. We describe some interesting design issues and how they were resolved, and point out some of the shortcomings of the current implementation. We conclude with some

Automating the Design of Graphical Presentations of Relational Information

by Jock Mackinlay - ACM Transactions on Graphics , 1986
"... The goal of the research described in this paper is to develop an application-independent presentation tool that automatically designs effective graphical presentations (such as bar charts, scatter plots, and connected graphs) of relational information. Two problems are raised by this goal: The codi ..."
Abstract - Cited by 559 (9 self) - Add to MetaCart
are sentences of graphical languages. The graphic design issues are codified as expressiveness and effectiveness criteria for graphical languages. Expressiveness criteria determine whether a graphical language can express the desired information. Effectiveness criteria determine whether a graphical language

Distributed Database Systems

by M. Tamer Özsu
"... this article, we discuss the fundamentals of distributed DBMS technology. We address the data distribution and architectural design issues as well as the algorithms that need to be implemented to provide the basic DBMS functions such as query processing, concurrency control, reliability, and replica ..."
Abstract - Cited by 588 (26 self) - Add to MetaCart
this article, we discuss the fundamentals of distributed DBMS technology. We address the data distribution and architectural design issues as well as the algorithms that need to be implemented to provide the basic DBMS functions such as query processing, concurrency control, reliability

The design of an acquisitional query processor for sensor networks

by Samuel Madden, Michael J. Franklin, Joseph M. Hellerstein, Wei Hong - In SIGMOD , 2003
"... We discuss the design of an acquisitional query processor for data collection in sensor networks. Acquisitional issues are those that pertain to where, when, and how often data is physically acquired (sampled) and delivered to query processing operators. By focusing on the locations and costs of acq ..."
Abstract - Cited by 523 (25 self) - Add to MetaCart
We discuss the design of an acquisitional query processor for data collection in sensor networks. Acquisitional issues are those that pertain to where, when, and how often data is physically acquired (sampled) and delivered to query processing operators. By focusing on the locations and costs

Image retrieval: Current techniques, promising directions and open issues

by Yong Rui, Thomas S. Huang - Journal of Visual Communication and Image Representation , 1999
"... This paper provides a comprehensive survey of the technical achievements in the research area of image retrieval, especially content-based image retrieval, an area that has been so active and prosperous in the past few years. The survey includes 100+ papers covering the research aspects of image fea ..."
Abstract - Cited by 507 (15 self) - Add to MetaCart
feature representation and extraction, multidimensional indexing, and system design, three of the fundamental bases of content-based image retrieval. Furthermore, based on the state-of-the-art technology available now and the demand from real-world applications, open research issues are identified

Design and Evaluation of a Compiler Algorithm for Prefetching

by Todd C. Mowry, Monica S. Lam, Anoop Gupta - in Proceedings of the Fifth International Conference on Architectural Support for Programming Languages and Operating Systems , 1992
"... Software-controlled data prefetching is a promising technique for improving the performance of the memory subsystem to match today's high-performance processors. While prefetching is useful in hiding the latency, issuing prefetches incurs an instruction overhead and can increase the load on the ..."
Abstract - Cited by 501 (20 self) - Add to MetaCart
Software-controlled data prefetching is a promising technique for improving the performance of the memory subsystem to match today's high-performance processors. While prefetching is useful in hiding the latency, issuing prefetches incurs an instruction overhead and can increase the load

Working Knowledge

by Thomas Davenport, Laurence Prusak, Gary Wills, Harith Alani, Ronald Ashri, Richard Crowder, Yannis Kalfoglou, Sanghee Kim , 1998
"... While knowledge is viewed by many as an asset, it is often difficult to locate particular items within a large electronic corpus. This paper presents an agent based framework for the location of resources to resolve a specific query, and considers the associated design issue. Aspects of the work ..."
Abstract - Cited by 527 (0 self) - Add to MetaCart
While knowledge is viewed by many as an asset, it is often difficult to locate particular items within a large electronic corpus. This paper presents an agent based framework for the location of resources to resolve a specific query, and considers the associated design issue. Aspects of the work

Routing Techniques in Wireless Sensor Networks: A Survey

by Jamal N. Al-karaki, Ahmed E. Kamal - IEEE WIRELESS COMMUNICATIONS , 2004
"... Wireless Sensor Networks (WSNs) consist of small nodes with sensing, computation, and wireless communications capabilities. Many routing, power management, and data dissemination protocols have been specifically designed for WSNs where energy awareness is an essential design issue. The focus, howeve ..."
Abstract - Cited by 741 (2 self) - Add to MetaCart
Wireless Sensor Networks (WSNs) consist of small nodes with sensing, computation, and wireless communications capabilities. Many routing, power management, and data dissemination protocols have been specifically designed for WSNs where energy awareness is an essential design issue. The focus
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