Microblogging is a new form of communication in which users can describe their current status in short posts distributed by instant messages, mobile phones, email or the Web. Twitter, a popular microblogging tool has seen a lot of growth since it launched in October, 2006. In this paper, we present

clinical significance, detection, pathogenesis, and preven-tion of anthracycline-induced cardiotoxicity. Data Sources: A MEDLINE search of the English-lan-guage medical literature and a manual search of the bib-liographies of relevant articles, including abstracts from national cardiology meetings. Study Selection: Pertinent clinical and experimental studies addressing the clinical relevance, pathogenesis, detection, and prevention of anthracycline cardiotoxicity were selected from peer-reviewed journals without judg-ments about study design. A total of 137 original studies and 9 other articles were chosen. Data Extraction: Data quality and validity were assessed by each author independently. Statistical analysis of com-bined data was inappropriate given the differences in

pharmacology and efficacy in acute leukemias. Use of newer antifolates in clinical trials trends in hematology

Abstract. The unexpected high bump in the UV part of the spectrum found in nearby giant elliptical galaxies, a.k.a. the UV upturn, has been a subject of debate. A remarkable progress has been made lately from the observational side, mainly involving space telescopes. The GALEX UV telescope has been obtaining thousands of giant ellipticals in the nearby universe, while HST is resolving local galaxies into stars and star clusters. An important clue has also been found regarding the origin of hot HB stars, and perhaps of sdB stars. That is, extreme amounts of helium are suspected to be the origin of the extended HB and even to the UV upturn phenomenon. A flurry of studies are pursuing the physics behind it. All this makes me optimistic that the origin of the UV upturn will be revealed in the next few years. I review some of the most notable progress and remaining issues. 1.

(Rs), peaks harply near Enceladus ' orbit (3.95 Rs) and has recently been found to be composed predominantly of grains l micrometer in radius. We study analytically and numerically the motion of such grains launched from Enceladus as they evolve under the action of Saturn's oblate gravity field, solar radiation pressure, and electromagnetic forces. The latter arise because grains are charged (usually to negative values) and also orbit through a dipolar mag-netic field. In the absence of planetary shadowing, solar radiation pressure cannot change an orbit's semimajor axis, but it can pro-duce periodic hanges in orbital eccentricity hat vary at the orbital precession rate. The orbital precession rates caused by the plane-tary oblateness and the Lorentz force on grains of 1 #m radius are shown to be approximately equal in magnitude but opposite in sign at Enceladus ' distance. The near-equality of these precessions for micrometer-sized grains introduced at Enceladus allows very large

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The brain is unique among virtually all somatic organs in its lack of a conventional lymphatic vasculature.1–3 In the periphery, the lymphatic circulation facilitates the clearance of extracellular proteins and excess fluid from the interstitium, a role critical to tissue homeostasis and function.4,5 Yet within the brain, despite its complex architecture and high metabolic activity and neural cells ’ sensitivity to changes in the extra-cellular environment, no specialized organ-wide anatomic structure has yet been identified that facilitates the efficient lymphatic clearance of extracellular solutes and fluid from the brain parenchyma.

M uch previous research has established that perceived ease of use is an important factor influencing user acceptance and usage behavior of information technologies. However, very little research has been conducted to understand how that perception forms and changes over time. The current work

various limitations of current recommendation methods and discusses possible extensions that can improve recommendation capabilities and make recommender systems applicable to an even broader range of applications. These extensions include, among others, an improvement of understanding of users and items

in current computer technology. Ontologies provide a shared and common understanding of a domain that can be communicated between people and application systems. Therefore, they may play a major role in supporting information exchange processes in various areas. This book discusses the role ontologies