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A quantitative description of membrane currents and its application to conduction and excitation in nerve

by A. L. Hodgkin, A. F. Huxley - Journal of Physiology , 1952
"... This article concludes a series of papers concerned with the flow of electric current through the surface membrane of a giant nerve fibre (Hodgkin, Huxley & Katz, 1952; Hodgkin & Huxley, 1952 a-c). Its general object is to discu the results of the preceding papers (Part I), to put them into ..."
Abstract - Cited by 1924 (2 self) - Add to MetaCart
in Fig. 1. Current can be carried through the membrane either by charging the membrane capacity or by movement of ion-s through the resistances in parallel with the capacity. The ionic current is divided into components carried by sodium and potassium ions (INa and IK), and a small 'leakage current

Image retrieval: Current techniques, promising directions and open issues

by Yong Rui, Thomas S. Huang - Journal of Visual Communication and Image Representation , 1999
"... This paper provides a comprehensive survey of the technical achievements in the research area of image retrieval, especially content-based image retrieval, an area that has been so active and prosperous in the past few years. The survey includes 100+ papers covering the research aspects of image fea ..."
Abstract - Cited by 507 (15 self) - Add to MetaCart
feature representation and extraction, multidimensional indexing, and system design, three of the fundamental bases of content-based image retrieval. Furthermore, based on the state-of-the-art technology available now and the demand from real-world applications, open research issues are identified

Determinants of perceived ease of use Integrating Control, Intrinsic Motivation, and Emotion into the Technology Acceptance Model.

by Viswanath Venkatesh - Information Systems Research , 2000
"... M uch previous research has established that perceived ease of use is an important factor influencing user acceptance and usage behavior of information technologies. However, very little research has been conducted to understand how that perception forms and changes over time. The current work pres ..."
Abstract - Cited by 493 (2 self) - Add to MetaCart
M uch previous research has established that perceived ease of use is an important factor influencing user acceptance and usage behavior of information technologies. However, very little research has been conducted to understand how that perception forms and changes over time. The current work

A framework for information systems architecture.

by J A Zachman - IBM Syst. J., , 1987
"... With increasing size and complexity of the implementations of information systems, it is necessary to use some logical construct (or architecture) for defining and controlling the interfaces and the integration of all of the components of the system. This paper defines information systems architect ..."
Abstract - Cited by 546 (0 self) - Add to MetaCart
are forcing the use of some logical construct (or architecture) for defining and controlling the interfaces and the integration of all of the components of the system. Thirty years ago this issue was not at all significant because the technology itself did not provide for either breadth in scope or depth

Principled design of the modern web architecture

by Roy T. Fielding, Richard N. Taylor - ACM Trans. Internet Techn
"... The World Wide Web has succeeded in large part because its software architecture has been designed to meet the needs of an Internet-scale distributed hypermedia system. The modern Web architecture emphasizes scalability of component interactions, generality of interfaces, independent deployment of c ..."
Abstract - Cited by 531 (14 self) - Add to MetaCart
The World Wide Web has succeeded in large part because its software architecture has been designed to meet the needs of an Internet-scale distributed hypermedia system. The modern Web architecture emphasizes scalability of component interactions, generality of interfaces, independent deployment

Ontologies: Silver Bullet for Knowledge Management and Electronic Commerce

by Dieter Fensel , 2007
"... Currently computers are changing from single isolated devices to entry points into a world wide network of information exchange and business transactions called the World Wide Web (WWW). Therefore support in the exchange of data, information, and knowledge exchange is becoming the key issue in cur ..."
Abstract - Cited by 656 (45 self) - Add to MetaCart
in current computer technology. Ontologies provide a shared and common understanding of a domain that can be communicated between people and application systems. Therefore, they may play a major role in supporting information exchange processes in various areas. This book discusses the role ontologies

An Overview of Workflow Management: From Process Modeling to Workflow Automation Infrastructure

by Diimitrios Georgakopoulos, Mark Hornick, Amit Sheth - DISTRIBUTED AND PARALLEL DATABASES , 1995
"... Today’s business enterprises must deal with global competition, reduce the cost of doing business, and rapidly develop new services and products. To address these requirements enterprises must constantly reconsider and optimize the way they do business and change their information systems and appl ..."
Abstract - Cited by 670 (26 self) - Add to MetaCart
) workflow automation to generate workflow implementations from workflow specifications. This paper provides a high-level overview of the current workflow management methodologies and software products. In addition, we discuss the infrastructure technologies that can address the limitations of current

Distributed Computing in Practice: The Condor Experience

by Douglas Thain, Todd Tannenbaum, Miron Livny , 2005
"... Since 1984, the Condor project has enabled ordinary users to do extraordinary computing. Today, the project continues to explore the social and technical problems of cooperative computing on scales ranging from the desktop to the world-wide computational Grid. In this paper, we provide the history a ..."
Abstract - Cited by 551 (8 self) - Add to MetaCart
and philosophy of the Condor project and describe how it has interacted with other projects and evolved along with the field of distributed computing. We outline the core components of the Condor system and describe how the technology of computing must correspond to social structures. Throughout, we reflect

Foundations for the Study of Software Architecture

by Dewayne E. Perry, Alexander L. Wolf - ACM SIGSOFT SOFTWARE ENGINEERING NOTES , 1992
"... The purpose of this paper is to build the foundation for software architecture. We first develop an intuition for software architecture by appealing to several well-established architectural disciplines. On the basis of this intuition, we present a model of software architec-ture that consists of th ..."
Abstract - Cited by 812 (35 self) - Add to MetaCart
of three components: elements, form, and rationale. Elements are either processing, data, or connecting elements. Form is defined in terms of the properties of, and the relationships among, the elements-- that is, the constraints on the elements. The ratio-nale provides the underlying basis

Induction of Decision Trees

by J. R. Quinlan - MACH. LEARN , 1986
"... The technology for building knowledge-based systems by inductive inference from examples has been demonstrated successfully in several practical applications. This paper summarizes an approach to synthesizing decision trees that has been used in a variety of systems, and it describes one such syste ..."
Abstract - Cited by 4377 (4 self) - Add to MetaCart
The technology for building knowledge-based systems by inductive inference from examples has been demonstrated successfully in several practical applications. This paper summarizes an approach to synthesizing decision trees that has been used in a variety of systems, and it describes one
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