Recent neurological studies indicate that the role of emotion in human cognition is essential; emotions are not a luxury. Instead, emotions play a critical role in rational decision-making, in perception, in human interaction, and in human intelligence. These facts, combined with abilities

The discovery of increased formation of methylglyoxal (MG) by cell metabolism in high glucose concentration in vitro suggested possible relevance to diabetes and di-abetes complications (1,2). MG is the precursor of quantitatively important advanced glycation end prod-ucts (AGEs) of protein and DNA- and MG-derived AGEs increase in experimental and clinical diabetes (3,4). In-creased MG and its metabolism by glyoxalase 1 (Glo1) was linked to clinical microvascular complications (ne-phropathy, retinopathy, and neuropathy) (5). Current clinical treatment decreasing MG and MG-derived AGEs, such as insulin lispro (6,7), has some clinical benefit in diabetic nephropathy (8), although the decrease in MG-derived AGE exposure is minor—;17 % (7). Greater benefits may be achieved with specific and effective anti-

natriuretic peptide receptor signaling and plays a

of networks and distributed systems. Ponder can also be used for security management activities such as registration of users or logging and auditing events for dealing with access to critical resources or security violations. Key concepts of the language include roles to group policies relating to a position

Given the central role that software development plays in the delivery and application of information technology, managers are increasingly focusing on process improvement in the software development area. This demand has spurred the provision of a number of new and/or improved approaches

We investigate the interaction between labour and credit market imperfections for the determination of equilibrium unemployment within the framework of the "right-tomanage " approach. Our analysis highlights the critical role of labour mobility for the evaluation of the employment

pRB, the product of the retinoblastoma tumor suppressor gene, operates in the midst of the cell cycle clock appara-tus. Its main role is to act as a signal transducer connecting the cell cycle clock with the transcriptional machinery. In this role, pRB allows the clock to control the expression

cold-start problem and incentive systems in emotional Web 2.0 services Abstract: Some content in multimedia resources can depict or evoke certain emotions in users. The aim of Emotional Information Retrieval (EmIR) is to identify knowledge about emotional-laden documents and to use these findings in a new kind of World Wide Web information service that allows users to search and browse by emotion. The cold-start problem arises in systems where users need to rate or tag documents when there is not sufficient information to draw interferences from these documents and the existing ratings or tags for those. The cold-start problem can be divided into three situations: cold-start system, coldstart user and cold-start item. In this paper we will refer to the first one and the last one. We will discuss the cold-start problem of the specialized search engine for emotional-laden multimedia documents called MEMOSE in this article and provide a solution using a combination of using content-based features to overcome the start-up phase and an incentive system for getting and keeping users motivated to use MEMOSE.

professional expertise, updated knowledge, critical thinking and involvement in developing effective AIDS literacy programs. Information professionals serving in different libraries or potential information dissemination centers can provide dedicated services to society by helping to access AIDS information

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