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gene cluster

by unknown authors
"... The rice plastid genes psaA and psaB encoding the two apoproteins ofP700 chlorophyll a protein complex of photosystem I reac-tion center, and the putative rpsl4 gene for ribosomal protein Sl4, are organized into a transcription u it. Northern blot analyses revealed that the polycistronic mRNA is tra ..."
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plastid evelopment is light-regulated primarily at translational or post-translational level. Sl-nuclease mapping and primer extension located the 5 ' end of the transcript predominantly at 175 bp upstream ofpsaA, and the 3 ' end at 116 bp downstream from rpsl4. The transcript is calculated tobe

RNA polymerase III transcribes human microRNAs.

by Glen M Borchert , William Lanier , Beverly L Davidson - Nature Struct. Mol. Biol. , 2006
"... Prior work demonstrates that mammalian microRNA (miRNA or miR) expression requires RNA polymerase II (Pol II). However, the transcriptional requirements of many miRNAs remain untested. Our genomic analysis of miRNAs in the human chromosome 19 miRNA cluster (C19MC) revealed that they are intersperse ..."
Abstract - Cited by 201 (3 self) - Add to MetaCart
. RESULTS miRNAs localize to repeats within the human genome We expanded prior studies by screening sequences flanking all known human miRNAs for repetitive elements (500 bp upstream and down stream) and annotating them using the Censor web server at the Genetic Information Research Institute 13 . Overall

A cis-acting element 7 bp upstream of the ESF-1-binding motif

by Ts Promoter, Brigitte M. Pu Tzer, Johanna Gnauck, H. -christoph Kirch, Dieter Brockmann, Helmut Esche
"... is involved in E1A 13S autoregulation of the adenovirus 12 ..."
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is involved in E1A 13S autoregulation of the adenovirus 12

Structure and function of the ζ-globin upstream regulatory element

by Daniel E. Sabath, Karen M. Koehler, Wei-qing Yang , 1996
"... The human ζ-globin promoter contains a strong posi-tive regulatory element in the 5 ′ flanking region, designated the ζ-globin upstream regulatory element (URE). In this study, we define the minimal sequences required for URE function and characterize the associated protein–DNA interactions. Deletio ..."
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as the other upstream factors. These results show that ζ-globin promoter function is highly dependent on a 60 bp region to which at least three different factors bind. Two of these factors may represent DNA-binding proteins not previously identified as important for regulation of globin gene expression

Cooperativity of Glucocorticoid Response Elements Located Far Upstream of the

by Tyrosine Aminotransferase Gene, Hans-michael Jantzen, Bernd Gloss, Francis Stewart, Wolfgang Schmid, Michael Boshart, Richard Miksicek, Gunther Schlitz
"... Two glucocorticoid response elements (GREs) located 2.5 kb upstream of the transcription initiation site of the tyrosine aminotransferase gene were identified by gene transfer experiments and shown to bind to puri-fied glucocorticoid receptor. Although the proximal GRE has no inherent capacity by it ..."
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by itself to stimulate transcription, when present in conjunction with the distal GRE, this element synergistically enhances glu-cocorticoid induction of gene expression. Coopera-tivity of the two GREs is maintained when they are transposed upstream of a heterologous promoter. An oligonucleotide of 22 bp

Does the Upstream Region Possessing MULE-Like Sequence in

by Rice Upregulate Psbs Gene Expression, Mohammed Nuruzzaman, Tatsuo Kanno, Rika Amada, Yoshiki Habu, Ichiro Kasajima, Toshiki Ishikawa, Maki Kawai-yamada, Hirofumi Uchimiya , 2014
"... The genomic nucleotide sequences of japonica rice (Sasanishiki and Nipponbare) contained about 2.7-kb unique region at the point of 0.4-kb upstream of the OsPsbS1 gene. In this study, we found that japonica rice with a few exceptions possessing such DNA sequences [denoted to OsMULE-japonica specific ..."
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The genomic nucleotide sequences of japonica rice (Sasanishiki and Nipponbare) contained about 2.7-kb unique region at the point of 0.4-kb upstream of the OsPsbS1 gene. In this study, we found that japonica rice with a few exceptions possessing such DNA sequences [denoted to Os

Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene

by Frank Kirchhoff, Harry W. Kestler Iii, J, Ronald C. Desrosiers - J Virol , 1994
"... Major transcriptional control elements are located within the U3 region of the long terminal repeats (LTRs) of lentivirus and other retroviral genomes. The nef auxiliary gene of simian immunodeficiency virus (SIV) and human immunodeficiency virus overlaps about 70 % of the 450- to 560-bp-long U3 reg ..."
Abstract - Cited by 23 (7 self) - Add to MetaCart
Major transcriptional control elements are located within the U3 region of the long terminal repeats (LTRs) of lentivirus and other retroviral genomes. The nef auxiliary gene of simian immunodeficiency virus (SIV) and human immunodeficiency virus overlaps about 70 % of the 450- to 560-bp-long U3

Two components of Saccharomyces cerevisiae transcription factor IIIB (TFIIIB) are stereospecifically located upstream of a tRNA gene and interact with the second-largest subunit of TFIIIC

by Blaine Bartholomew, George A. Kassavetis, E. Peter Geiduschek - Mol. Cell. Biol , 1991
"... A novel photocrosslinking method has been used to identify the components of transcription factor IIIB (TFIIIB) and TFIHC that associate with DNA upstream of the Saccharomyces cerevisiae SUP4 tRNATYF gene and to map these components to specific positions in DNA. When TFIIIC binds to the tRNA gene, o ..."
Abstract - Cited by 27 (3 self) - Add to MetaCart
Da) within reach of upstream photoprobes. A collection of 13 probes has been used to map the locations of these three proteins along a 45-bp segment of DNA upstream of the transcriptional start site. Evidence is presented that the 90- and 70-kDa polypeptides are separate and distinct components of yeast

V (2008) L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer

by Yu Han - Mol Cell Biol
"... The Sry-related high-mobility-group box transcription factor Sox9 recruits the redundant L-Sox5 and Sox6 proteins to effect chondrogenesis, but the mode of action of the trio remains unclear. We identify here a highly conserved 359-bp sequence 10 kb upstream of the Agc1 gene for aggrecan, a most ess ..."
Abstract - Cited by 33 (0 self) - Add to MetaCart
The Sry-related high-mobility-group box transcription factor Sox9 recruits the redundant L-Sox5 and Sox6 proteins to effect chondrogenesis, but the mode of action of the trio remains unclear. We identify here a highly conserved 359-bp sequence 10 kb upstream of the Agc1 gene for aggrecan, a most

Modulation of in vitro splicing of the upstream intron by modifying an intra-exon sequence which is deleted from the dystrophin gene in dystrophin Kobe

by Yasuhiro Takeshima, Hisahide Nishio, Hiroshi Sakamoto, Hajime Nakamura, Masafumi Matsuo, T. Masumura, H. Nishio, T. Nakajima, Y. Kitoh, T. Takumi, J. Koga - J. Clin. Invest , 1995
"... Molecular analysis of dystrophin Kobe showed that exon 19 of the dystrophin gene bearing 52-bp deletion was skipped during splicing, although the known consensus sequences at the 5 ' and 3 ' splice sites of exon 19 were maintained (Mat- ..."
Abstract - Cited by 15 (4 self) - Add to MetaCart
Molecular analysis of dystrophin Kobe showed that exon 19 of the dystrophin gene bearing 52-bp deletion was skipped during splicing, although the known consensus sequences at the 5 ' and 3 ' splice sites of exon 19 were maintained (Mat-
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