Results 1  10
of
5,278
Integrative analysis of cancer gene expression studies using Bayesian latent factor modelling. Annals of Applied Statistics
, 2009
"... We present an applied study in cancer genomics for integrating data and inferences from laboratory experiments on cancer cell lines with observational data obtained from human breast cancer studies. The biological focus is on improving understanding of transcriptional responses of tumors to changes ..."
Abstract

Cited by 5 (2 self)
 Add to MetaCart
contexts. The statistical methodologies employed here draw heavily on Bayesian sparse factor models for identifying, modularizing, and correlating with clinical outcome these signatures of aggregate changes in gene expression. By projecting patterns of biological response linked to specific experimental
Latent dirichlet allocation
 Journal of Machine Learning Research
, 2003
"... We describe latent Dirichlet allocation (LDA), a generative probabilistic model for collections of discrete data such as text corpora. LDA is a threelevel hierarchical Bayesian model, in which each item of a collection is modeled as a finite mixture over an underlying set of topics. Each topic is, ..."
Abstract

Cited by 4365 (92 self)
 Add to MetaCart
We describe latent Dirichlet allocation (LDA), a generative probabilistic model for collections of discrete data such as text corpora. LDA is a threelevel hierarchical Bayesian model, in which each item of a collection is modeled as a finite mixture over an underlying set of topics. Each topic is
Probabilistic Latent Semantic Indexing
, 1999
"... Probabilistic Latent Semantic Indexing is a novel approach to automated document indexing which is based on a statistical latent class model for factor analysis of count data. Fitted from a training corpus of text documents by a generalization of the Expectation Maximization algorithm, the utilized ..."
Abstract

Cited by 1225 (10 self)
 Add to MetaCart
Probabilistic Latent Semantic Indexing is a novel approach to automated document indexing which is based on a statistical latent class model for factor analysis of count data. Fitted from a training corpus of text documents by a generalization of the Expectation Maximization algorithm, the utilized
Unsupervised Learning by Probabilistic Latent Semantic Analysis
 Machine Learning
, 2001
"... Abstract. This paper presents a novel statistical method for factor analysis of binary and count data which is closely related to a technique known as Latent Semantic Analysis. In contrast to the latter method which stems from linear algebra and performs a Singular Value Decomposition of cooccurren ..."
Abstract

Cited by 618 (4 self)
 Add to MetaCart
Abstract. This paper presents a novel statistical method for factor analysis of binary and count data which is closely related to a technique known as Latent Semantic Analysis. In contrast to the latter method which stems from linear algebra and performs a Singular Value Decomposition of co
Variational algorithms for approximate Bayesian inference
, 2003
"... The Bayesian framework for machine learning allows for the incorporation of prior knowledge in a coherent way, avoids overfitting problems, and provides a principled basis for selecting between alternative models. Unfortunately the computations required are usually intractable. This thesis presents ..."
Abstract

Cited by 440 (9 self)
 Add to MetaCart
a unified variational Bayesian (VB) framework which approximates these computations in models with latent variables using a lower bound on the marginal likelihood. Chapter 1 presents background material on Bayesian inference, graphical models, and propagation algorithms. Chapter 2 forms
Dynamic Bayesian Networks: Representation, Inference and Learning
, 2002
"... Modelling sequential data is important in many areas of science and engineering. Hidden Markov models (HMMs) and Kalman filter models (KFMs) are popular for this because they are simple and flexible. For example, HMMs have been used for speech recognition and biosequence analysis, and KFMs have bee ..."
Abstract

Cited by 770 (3 self)
 Add to MetaCart
been used for problems ranging from tracking planes and missiles to predicting the economy. However, HMMs
and KFMs are limited in their “expressive power”. Dynamic Bayesian Networks (DBNs) generalize HMMs by allowing the state space to be represented in factored form, instead of as a single discrete
The unity and diversity of executive functions and their contributions to complex “Frontal Lobe” tasks: a latent variable analysis
 COGNIT PSYCHOL
, 2000
"... This individual differences study examined the separability of three often postulated executive functions—mental set shifting ("Shifting"), information updating and monitoring ("Updating"), and inhibition of prepotent responses ("Inhibition")—and their roles in complex ..."
Abstract

Cited by 696 (9 self)
 Add to MetaCart
Sorting Test (WCST), Tower of Hanoi (TOH), random number generation (RNG), operation span, and dual tasking. Confirmatory factor analysis indicated that the three target executive functions are moderately correlated with one another, but are clearly separable. Moreover, structural equation modeling
Factor Graphs and the SumProduct Algorithm
 IEEE TRANSACTIONS ON INFORMATION THEORY
, 1998
"... A factor graph is a bipartite graph that expresses how a "global" function of many variables factors into a product of "local" functions. Factor graphs subsume many other graphical models including Bayesian networks, Markov random fields, and Tanner graphs. Following one simple c ..."
Abstract

Cited by 1791 (69 self)
 Add to MetaCart
A factor graph is a bipartite graph that expresses how a "global" function of many variables factors into a product of "local" functions. Factor graphs subsume many other graphical models including Bayesian networks, Markov random fields, and Tanner graphs. Following one simple
Probabilistic Principal Component Analysis
 JOURNAL OF THE ROYAL STATISTICAL SOCIETY, SERIES B
, 1999
"... Principal component analysis (PCA) is a ubiquitous technique for data analysis and processing, but one which is not based upon a probability model. In this paper we demonstrate how the principal axes of a set of observed data vectors may be determined through maximumlikelihood estimation of paramet ..."
Abstract

Cited by 709 (5 self)
 Add to MetaCart
of parameters in a latent variable model closely related to factor analysis. We consider the properties of the associated likelihood function, giving an EM algorithm for estimating the principal subspace iteratively, and discuss, with illustrative examples, the advantages conveyed by this probabilistic approach
Probabilistic Inference Using Markov Chain Monte Carlo Methods
, 1993
"... Probabilistic inference is an attractive approach to uncertain reasoning and empirical learning in artificial intelligence. Computational difficulties arise, however, because probabilistic models with the necessary realism and flexibility lead to complex distributions over highdimensional spaces. R ..."
Abstract

Cited by 736 (24 self)
 Add to MetaCart
Probabilistic inference is an attractive approach to uncertain reasoning and empirical learning in artificial intelligence. Computational difficulties arise, however, because probabilistic models with the necessary realism and flexibility lead to complex distributions over highdimensional spaces
Results 1  10
of
5,278