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Activated Kinases To Stimulate AP-1 Activity

by J A Frost, A S Alberts, E Sontag, K Guan, M C Mumby, Jeffrey A. Frost, T Arthur S. Alberts, T Estelle Sontag, Kunliang Guan, Marc C. Mumby, James R. Feramisco , 1994
"... Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity. ..."
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Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity.

by Quenching AP-1 Activity

by M J O'connor, S H Tan, C H Tan, H U Bernard, J. Virol, Mark J. O’connor, Shyh-han Tan, Chiew-hoon Tan, Hans-ulrich Bernard , 1996
"... These include: Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this article), more» Downloaded from ..."
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These include: Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this article), more» Downloaded from

1 Opposite effects of rofecoxib on NF-κB and AP-1 activation1

by Ellen Niederberger, Irmgard Tegeder, Christine Schäfer, Maic Seegel, Sabine Grösch, Gerd Geisslinger, Pharmazentrum Frankfurt, Klinikum Johann, Wolfgang Goethe-universität Frankfurt, Ellen Niederberger Phd
"... 2 Running title: AP-1 activation and NF-κB inhibition through rofecoxib ..."
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2 Running title: AP-1 activation and NF-κB inhibition through rofecoxib

implication of ERK pathway and AP-1 activation

by Julie Blanchette, Martin Olivier
"... Role of protein tyrosine phosphatases in the regulation of ..."
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Role of protein tyrosine phosphatases in the regulation of

the Transcription Factor AP-1 Activity by Glucocorticoid Receptor

by Forschungszentrum Karlsruhe, Wissenschaftliche Berichte, Phosphorylation Trans, S. Sekula, Forschungszentrum Karlsruhe, Wissenschaftliche Berichte, Sylwia Sekula
"... Inhibition of c-Jun/ATF2 phosphorylation, Trans-repression of c-Jun/c-Fos: Two modes of regulation of the transcription factor ..."
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Inhibition of c-Jun/ATF2 phosphorylation, Trans-repression of c-Jun/c-Fos: Two modes of regulation of the transcription factor

Coactivator MBF1 preserves the redox-dependent AP-1 activity during oxidative stress in Drosophila

by Marek Jindra, Ivana Gaziova, Masataka Okabe, Susumu Hirose - EMBO J , 2004
"... Basic leucine zipper proteins Jun and Fos form the dimeric transcription factor AP-1, essential for cell differentiation and immune and antioxidant defenses. AP-1 activity is controlled, in part, by the redox state of critical cysteine residues within the basic regions of Jun and Fos. Mutation of th ..."
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Basic leucine zipper proteins Jun and Fos form the dimeric transcription factor AP-1, essential for cell differentiation and immune and antioxidant defenses. AP-1 activity is controlled, in part, by the redox state of critical cysteine residues within the basic regions of Jun and Fos. Mutation

Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo

by Rachel Schiff, Praveen Reddy, Markku Ahotupa Ester, Coronado-heinsohn Matt Grim, Susan G. Hilsenbeck, Susan Deneke, Suzanne A. W. Fuqua, Powel H, C. Kent Osborne - J. Natl. Cancer Inst. (Bethesda
"... Background: Most breast cancers, even those that are initially responsive to tamoxifen, ultimately become resistant. The molecular basis for this resistance, which in some patients is thought to involve stimulation of tumor growth by tamoxifen, is unclear. Tamoxifen induces cellular oxidative stress ..."
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stress, and because changes in cell redox state can activate signaling pathways leading to the activation of activating protein-1 (AP-1), we investigated whether tamoxifen-resistant growth in vivo is associated with oxidative stress and/or activation of AP-1 in a xenograft model

Signaling Pathways Leading to AP-1 Activation and c-Fos Expression 1

by Amy L. Silvers, Michael A. Bachelor, G. Timothy Bowden
"... To further delineate ultraviolet A (UVA) signaling pathways in the human keratinocyte cell line HaCaT, we examined the potential role of mitogen-activated protein kinases (MAPKs) in UVA-induced activator protein-1 (AP-1) transactivation and c-Fos expression. UVA-induced phosphorylation of p38 and c- ..."
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To further delineate ultraviolet A (UVA) signaling pathways in the human keratinocyte cell line HaCaT, we examined the potential role of mitogen-activated protein kinases (MAPKs) in UVA-induced activator protein-1 (AP-1) transactivation and c-Fos expression. UVA-induced phosphorylation of p38 and c

The estrogen receptor enhances AP1 activity by two distinct mechanisms with different requirements for receptor transactivation functions

by Paul Webb, Phuong Nguyen, Cathleen Valentine, Gabriela N. Lopez, Grace R. Kwok, Eileen Mcinerney, Benita S. Katzenellenbogen, Eva Enmark, Jan-åke Gustafsson, Stefan Nilsson, Peter J. Kushner, Karobio Ab (s. N - Mol. Endocrinol , 1999
"... Estrogen receptors (ERs � and �) enhance transcription in response to estrogens by binding to estrogen response elements (EREs) within target genes and utilizing transactivation functions (AF-1 and AF-2) to recruit p160 coactivator proteins. The ERs also enhance transcription in response to estrogen ..."
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to estrogens and antiestrogens by modulating the activity of the AP-1 protein complex. Here, we examine the role of AF-1 and AF-2 in ER action at AP-1 sites. Estrogen responses at AP-1 sites require the integrity of the ER � AF-1 and AF-2 activation surfaces and the complementary surfaces on the p160

AP-1 Activator protein 1 ATCC American Type Culture Collection

by Hanna Piotrowska, Malgorzata Kucinska, Marek Murias, Ca Human Cervical Carcinoma
"... Abstract The expression of P450 enzymes and antioxi-dative enzymes in tumour tissue can have a major impact on the responsiveness of tumours to cancer chemotherapeutic drugs, therefore such information may be very precious when experiments are designed. The compressive informa-tion, concerning the e ..."
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, lack of cancer cell specific CYP1B1 protein was discovered in LOVO colorectal cells. In order to test possible correlation between expression of CYP1A1, CYP1B1 and MnSOD and modulators of their activity, cytotoxicity of resveratrol and its promising hydroxylated analogue 3,30,4,40,5,50-trans
Results 1 - 10 of 3,326