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4,410
Cytological Alterations and Antitumoral Activity
"... Peritoneal macrophages from mice injected with aclacinomycin (ACM) (4 mg/kg, i.p.) showed increased functional activity, as assessed by increased antitumoral activity in vitro and in vivo and zymosan-triggered chemoluminescence. They also showed ultrastructural signs of activation (increased number ..."
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Peritoneal macrophages from mice injected with aclacinomycin (ACM) (4 mg/kg, i.p.) showed increased functional activity, as assessed by increased antitumoral activity in vitro and in vivo and zymosan-triggered chemoluminescence. They also showed ultrastructural signs of activation (increased number
Evaluation of the Antitumor Activity of Gemcitabine
, 2013
"... A new pyrimidine antimetabolite, 2',2'-difluorodeoxycytidine, Gem citabine (LY188011, dFdCyd) has been synthesized and evaluated in experimental tumor models. dFdCyd is a very potent and specific deoxy cytidine analogue. The concentration required for 50 % inhibition of growth is 1 ng/ml i ..."
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agent. Maximal activity in vivo was seen with dFdCyd when administered on an every third day schedule. 1-/3-D-Arabinofuranosylcytosine, administered on a daily for 10-day sched ule, was directly compared to dFdCyd in this evaluation. dFdCyd dem onstrated good to excellent antitumor activity in eight
IN VITRO ANTIOXIDANT AND ANTITUMOR ACTIVITY OF
"... journal published quarterly. The Aim of IJPBS is to publish peer reviewed research and review articles in less time without much delay in the developing field of Pharmaceutical and Biological sciences. One week from the date of manuscript submission author gets the decision of acceptance and if acce ..."
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journal published quarterly. The Aim of IJPBS is to publish peer reviewed research and review articles in less time without much delay in the developing field of Pharmaceutical and Biological sciences. One week from the date of manuscript submission author gets the decision of acceptance and if accepted the manuscript will be processed within 3 weeks (approx.) for publication.
induce additive antitumor activity
"... Small-molecule inhibition of proteasome and silencing by vascular endothelial cell growth factor-specific siRNA ..."
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Small-molecule inhibition of proteasome and silencing by vascular endothelial cell growth factor-specific siRNA
and Antitumor Activity in a
"... reduced tumor burden in the peritoneal cavity of mice and sig-nificantly increased their survival. Analysis of vascular changes and PTX tumor uptake in vandetanib-treated tumors may help to guide the scheduling of vandetanib plus PT n of clinical trials with these drugs. Neoplasia (2009) 11, 1155–11 ..."
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reduced tumor burden in the peritoneal cavity of mice and sig-nificantly increased their survival. Analysis of vascular changes and PTX tumor uptake in vandetanib-treated tumors may help to guide the scheduling of vandetanib plus PT n of clinical trials with these drugs. Neoplasia (2009) 11, 1155–1164
ANTITUMOR ACTIVITY OF THE CARBOPLATIN-o-CYCLODEXTRIN
"... Antitumor activity of the adduct between Carboplatin and (z-cyclodextrin has been tested against Sarcoma 180 ($18o) and Ehrlich ascites carcinoma (EAC) murine tumors. The preliminary toxicity has also been evaluated by histological examinations of the treated animals. The results show the adduct has ..."
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Antitumor activity of the adduct between Carboplatin and (z-cyclodextrin has been tested against Sarcoma 180 ($18o) and Ehrlich ascites carcinoma (EAC) murine tumors. The preliminary toxicity has also been evaluated by histological examinations of the treated animals. The results show the adduct
Antitumor Activities of Kushen: Literature Review
"... To discover and develop novel natural compounds with therapeutic selectivity or that can preferentially kill cancer cells without significant toxicity to normal cells is an important area in cancer chemotherapy. Kushen, the dried roots of Sophora flavescens Aiton, has a long history of use in tradi ..."
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activities were identified in KS-Fs than in KS-As in vitro and in vivo. KS-Fs may be developed as novel antitumor agents.
Synthesis and Antitumor Activity of Poly(organophosphazene)/
, 1998
"... Doxorubicin shows a wide spectrum of activity for solid tumors such as sarcomas, adenocarcinomas and melanomas, but its strong side effects including myelosuppression, extravasation reaction and cardiotoxicity have been a serious problem.1 Polymer-anticancer drug conjugates have been studied in orde ..."
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~5 In addition, polymer-anticancer drug conju-gates can afford to prolong the antitumor activity by releas-ing the drug with a controlled rate. Several polymer-doxorubicin conjugates have been studied, and among them, N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer/ doxorubicin conjugate is currently under
Results 1 - 10
of
4,410
