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Adenoviral gene transfer in a rat fracture model
"... Adenoviral gene transfer in a rat fracture model ..."
Adenoviral gene transfer of active human transforming growth factor-
- Visual Science
, 2010
"... PURPOSE. Glaucoma is a leading cause worldwide of blindness and visual impairment. Transforming growth factor-2 (TGF2) has been implicated in the pathogenesis of primary open-angle glaucoma (POAG) based on elevated levels in glaucomatous aqueous humor and its ability to induce extracellular matri ..."
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Cited by 1 (0 self)
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. Adenoviral gene transfer of hTGF2 226/228 , but not hTGF2 WT , to the rodent eye elevated IOP in rat (43%, P Ͻ 0.001) and mouse (110%, P Ͻ 0.001) and reduced aqueous humor outflow facility in the mouse. The TGF2-induced ocular hypertension correlated with anterior segment TGF2 expression levels (P Ͻ 0
TNF receptor secretion after ex vivo adenoviral gene transfer
, 2001
"... PURPOSE. To explore the potential for adenovirus-mediated ex vivo gene transfer of a soluble tumor necrosis factor (TNF) receptor and evaluate the effect of transplanting the adenovirally transplanted corneas in vivo. METHODS. Rabbit corneal segments were transfected with replication-deficient adeno ..."
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PURPOSE. To explore the potential for adenovirus-mediated ex vivo gene transfer of a soluble tumor necrosis factor (TNF) receptor and evaluate the effect of transplanting the adenovirally transplanted corneas in vivo. METHODS. Rabbit corneal segments were transfected with replication
Mesenchymal Stem Cells by Combined Co-stimulation Mediated by Adenoviral Gene Transfer
, 2012
"... This Provisional PDF corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. ..."
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This Provisional PDF corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon.
ADENOVIRUS ENDOCYTOSIS AND ADENOVIRAL GENE TRANSFER IN CARDIOVASCULAR AND DERMATOLOGIC DISEASE MODELS
, 2004
"... Academic Dissertation to be presented with the assent of ..."
Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis
"... Connective tissue growth factor (CTGF) is felt to be one of the key profibrotic factors and is a downstream effector molecule mediating the action of transforming growth factor (TGF)–�1, a cytokine known to induce severe and progressive fibrosis. However, the in vivo fibrogenic effect of isolated CT ..."
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CTGF expression is not well described. We used adenoviral gene transfer to transiently overexpress CTGF in rat lungs after intratracheal administration and compared it with transient overexpression of active TGF-�1 delivered by a similar adenovirus vector. This high expression of CTGF over 6–10 days
Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck
- Cancer Res
, 1995
"... Cancer gene therapy strategies for inducing apoptosis in solid tumors may allow contemporary medicine to reassess its management of these cancers. We demonstrated previously that overexpression of the wild-type /»5.à • gene in squamous cell carcinoma of the head and neck cell lines via adenovirus-m ..."
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Cited by 5 (2 self)
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-mediated gene transfer suppressed growth both in vitro and in vivo. Here, we characterize the mechanism of the growth suppression by the exogenous p53 gene as a consequence of programmed cell death (apoptosis). One of the cell lines used in this study, Tu-138, harbors a mutated p53 gene, whereas the other cell
Overexpression of Protein Kinase C β Isoform by Adenoviral Gene Transfer Accelerated Intimal Hyperplasia in Rat Carotid Artery
"... Abstract: Vigorous restenosis is responsible for high failure rates of angioplasty in diabetic patients. Since protein kinase C (PKC)β isoform activation is associated with vascular complications of diabetes, we have determined whether PKCβ isoform overexpression can stimulate growth and migration o ..."
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patients. Key words: protein kinase C, restenosis, gene transfer, diabetes.
Adenoviral Gene Transfer of Fortilin Attenuates Neointima Formation Through Suppression of Vascular Smooth Muscle Cell Proliferation and Migration
, 2003
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The online version of this article, along with updated information and services, is located on the
Restoration of Diastolic Function in Senescent Rat Hearts Through Adenoviral Gene Transfer of Sarcoplasmic
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The online version of this article, along with updated information and services, is located on the
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