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22,871
Molecular Computation Of Solutions To Combinatorial Problems
, 1994
"... The tools of molecular biology are used to solve an instance of the directed Hamiltonian path problem. A small graph is encoded in molecules of DNA and the `operations' of the computation are performed with standard protocols and enzymes. This experiment demonstrates the feasibility of carrying ..."
Abstract
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Cited by 773 (6 self)
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of carrying out computations at the molecular level.
Modeling and simulation of genetic regulatory systems: A literature review
- JOURNAL OF COMPUTATIONAL BIOLOGY
, 2002
"... In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between ..."
Abstract
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Cited by 738 (14 self)
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In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between
UCSF Chimera—a visualization system for exploratory research and analysis
- J. Comput. Chem
, 2004
"... Abstract: The design, implementation, and capabilities of an extensible visualization system, UCSF Chimera, are discussed. Chimera is segmented into a core that provides basic services and visualization, and extensions that provide most higher level functionality. This architecture ensures that the ..."
Abstract
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Cited by 504 (7 self)
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Abstract: The design, implementation, and capabilities of an extensible visualization system, UCSF Chimera, are discussed. Chimera is segmented into a core that provides basic services and visualization, and extensions that provide most higher level functionality. This architecture ensures
Comparison of discrimination methods for the classification of tumors using gene expression data
- JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
, 2002
"... A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel biotechnologies increasingly used in cancer research. By allowing the monitoring of expression levels in cells for thousand ..."
Abstract
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Cited by 770 (6 self)
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A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel biotechnologies increasingly used in cancer research. By allowing the monitoring of expression levels in cells
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res
"... Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time PCR is easy to perform, provides the necessary accuracy and produces reliable as ..."
Abstract
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Cited by 1088 (4 self)
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Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time PCR is easy to perform, provides the necessary accuracy and produces reliable
Computational Studies at the Molecular Level
"... Conformational behaviour of amphiphilic molecules in aqueous solution and at a water/air interface: computational studies at the molecular level ..."
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Conformational behaviour of amphiphilic molecules in aqueous solution and at a water/air interface: computational studies at the molecular level
PHENIX: a comprehensive Python-based system for macromolecular structure solution
- Acta Crystallogr. D Biol. Crystallogr
, 2010
"... Macromolecular X-ray crystallography is routinely applied to understand biological processes at a molecular level. However, significant time and effort are still required to solve and complete many of these structures because of the need for manual interpretation of complex numerical data using many ..."
Abstract
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Cited by 418 (5 self)
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Macromolecular X-ray crystallography is routinely applied to understand biological processes at a molecular level. However, significant time and effort are still required to solve and complete many of these structures because of the need for manual interpretation of complex numerical data using
Re-Tiling Polygonal Surfaces
- Computer Graphics
, 1992
"... This paper presents an automatic method of creating surface models at several levels of detail from an original polygonal description of a given object. Representing models at various levels of detail is important for achieving high frame rates in interactive graphics applications and also for speed ..."
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Cited by 445 (3 self)
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This paper presents an automatic method of creating surface models at several levels of detail from an original polygonal description of a given object. Representing models at various levels of detail is important for achieving high frame rates in interactive graphics applications and also
Specificity and stability in topology of protein networks
- Science
, 2002
"... Molecular networks guide the biochemistry of a living cell on multiple levels: its metabolic and signalling pathways are shaped by the network of interacting proteins, whose production, in turn, is controlled by the genetic regulatory network. To address topological properties of these two networks ..."
Abstract
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Cited by 408 (3 self)
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Molecular networks guide the biochemistry of a living cell on multiple levels: its metabolic and signalling pathways are shaped by the network of interacting proteins, whose production, in turn, is controlled by the genetic regulatory network. To address topological properties of these two networks
Results 1 - 10
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22,871
