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unknown title

by Surjit Kaila, S. Srai
"... HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA–forming microsatellite ..."
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HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA–forming microsatellite

unknown title

by Henry K. Bayele, Carole Peyssonnaux, Ra Giatromanolaki, Wagner W. Arrais-silva, Hiba S. Mohamed, Helen Collins, Selma Giorgio, Michael Koukourakis, All S. Johnson, Jenefer M. Blackwell, Victor Nizet, Surjit Kaila, S. Srai
"... HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA–forming microsatellite ..."
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HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA–forming microsatellite

Characterization of monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.J. Exp. Med

by C. Unkeless , 1979
"... Fc receptors 1 (FcR) recognize the Fc domain of IgG and are found on macrophages, lymphocytes, and polymorphonuclear leukocytes (for reviews see Kerbel and Davies [1] and Dickler[2]). These receptors enable the effector cells to recognize foreign antigens to which antibodies are bound and may also p ..."
Abstract - Cited by 183 (7 self) - Add to MetaCart
play a role in immune responsiveness (3). Although there have been reports of isolation of FcR from various cell types, there is as yet no general agreement on structure or properties. Peptides with apparent molecular weights ranging from 125,000 to 28,000 have been isolated by affinity chromatography

S.H.: A genome-wide association study of global gene expression.

by Anna L Dixon , Liming Liang , Miriam F Moffatt , Wei Chen , Simon Heath , Kenny C C Wong , Jenny Taylor , Edward Burnett , Ivo Gut , Martin Farrall , G Mark Lathrop , Gonçalo R Abecasis , William O C Cookson - Nature Genetics , 2007
"... We have created a global map of the effects of polymorphism on gene expression in 400 children from families recruited through a proband with asthma. We genotyped 408,273 SNPs and identified expression quantitative trait loci from measurements of 54,675 transcripts representing 20,599 genes in Epst ..."
Abstract - Cited by 242 (11 self) - Add to MetaCart
traits were markedly enriched in Gene Ontology descriptors for response to unfolded protein (chaperonins and heat shock proteins), regulation of progression through the cell cycle, RNA processing, DNA repair, immune responses and apoptosis. SNPs that regulate expression of these genes are candidates

Toll-like receptor activation of XBP1 regulates innate immune responses

by Fabio Martinon, Xi Chen, Ann-hwee Lee, Laurie H. Glimcher
"... in macrophages ..."
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in macrophages

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates.

by Andreas Pichlmair , Oliver Schulz , Choon Ping Tan , Tanja I Näslund , Peter Liljeström , Friedemann Weber , Caetano Reis E Sousa - Science , 2006
"... Double-stranded RNA (dsRNA) produced during viral replication is believed to be the critical trigger for activation of antiviral immunity mediated by the RNA helicase enzymes RIG-I and MDA5. Here, we show that influenza A virus infection does not generate dsRNA and that RIG-I is activated by single ..."
Abstract - Cited by 217 (6 self) - Add to MetaCart
Double-stranded RNA (dsRNA) produced during viral replication is believed to be the critical trigger for activation of antiviral immunity mediated by the RNA helicase enzymes RIG-I and MDA5. Here, we show that influenza A virus infection does not generate dsRNA and that RIG-I is activated

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role

by Simon Read, Vivianne Malmström, Fiona Powrie - in the function of CD25 � CD4 , 2000
"... It is now clear that functionally specialized regulatory T (Treg) cells exist as part of the normal immune repertoire, preventing the development of pathogenic responses to both self- and intestinal antigens. Here, we report that the Treg cells that control intestinal inflammation express the same p ..."
Abstract - Cited by 224 (9 self) - Add to MetaCart
It is now clear that functionally specialized regulatory T (Treg) cells exist as part of the normal immune repertoire, preventing the development of pathogenic responses to both self- and intestinal antigens. Here, we report that the Treg cells that control intestinal inflammation express the same

RESEARCH ARTICLE Modulation of Human Macrophage Responses toMycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface

by Srijata Sarkar, Bey Fen Leo, Claudia Carranza, Shu Chen, Cesar Rivas-santiago, Ra E. Porter, Mary P. Ryan, Andrew Gow, Kian Fan Chung, Teresa D. Tetley, Junfeng (jim Zhang, Panos G. Georgopoulos, Pamela A. Ohman-strickl, Stephan Schwander
"... Exposure to silver nanoparticles (AgNP) used in consumer products carries potential health risks including increased susceptibility to infectious pathogens. Systematic assessments of antimicrobial macrophage immune responses in the context of AgNP exposure are impor-tant because uptake of AgNP by ma ..."
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Exposure to silver nanoparticles (AgNP) used in consumer products carries potential health risks including increased susceptibility to infectious pathogens. Systematic assessments of antimicrobial macrophage immune responses in the context of AgNP exposure are impor-tant because uptake of Ag

Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment

by Sabine Ehrt, Martin I. Voskuil, Yang Liu, Joseph A. Mangan, Irene M. Monahan, Gregory Dolganov, Brad Efron, Philip D. Butcher, Carl Nathan, Gary K. Schoolnik - J Exp Med , 2003
"... Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of Mycobacterium tuberculosis (MTB) in macrophages from wild-type and nitric oxide (NO) synthase 2–deficient mice before and ..."
Abstract - Cited by 167 (11 self) - Add to MetaCart
Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of Mycobacterium tuberculosis (MTB) in macrophages from wild-type and nitric oxide (NO) synthase 2–deficient mice before

situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

by Joshy Jacob, Garnett Kelsoe , 1991
"... In the genetically restricted response that follows immunization with (4-hydroxy-3-nitrophenyl)acetyl coupled to protein carriers, two distinct populations of B cells are observed in the spleens of C57BL/6 mice. By 48 h postimmunization, loci of antigen-binding B cells appear along the periphery of ..."
Abstract - Cited by 171 (6 self) - Add to MetaCart
In the genetically restricted response that follows immunization with (4-hydroxy-3-nitrophenyl)acetyl coupled to protein carriers, two distinct populations of B cells are observed in the spleens of C57BL/6 mice. By 48 h postimmunization, loci of antigen-binding B cells appear along the periphery
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