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A comparison of bayesian methods for haplotype reconstruction from population genotype data.

by Matthew Stephens , Peter Donnelly , Dr Matthew Stephens - Am J Hum Genet , 2003
"... In this report, we compare and contrast three previously published Bayesian methods for inferring haplotypes from genotype data in a population sample. We review the methods, emphasizing the differences between them in terms of both the models ("priors") they use and the computational str ..."
Abstract - Cited by 557 (7 self) - Add to MetaCart
In this report, we compare and contrast three previously published Bayesian methods for inferring haplotypes from genotype data in a population sample. We review the methods, emphasizing the differences between them in terms of both the models ("priors") they use and the computational

Bayesian Model Selection in Social Research (with Discussion by Andrew Gelman & Donald B. Rubin, and Robert M. Hauser, and a Rejoinder)

by Adrian Raftery - SOCIOLOGICAL METHODOLOGY 1995, EDITED BY PETER V. MARSDEN, CAMBRIDGE,; MASS.: BLACKWELLS. , 1995
"... It is argued that P-values and the tests based upon them give unsatisfactory results, especially in large samples. It is shown that, in regression, when there are many candidate independent variables, standard variable selection procedures can give very misleading results. Also, by selecting a singl ..."
Abstract - Cited by 585 (21 self) - Add to MetaCart
single model, they ignore model uncertainty and so underestimate the uncertainty about quantities of interest. The Bayesian approach to hypothesis testing, model selection and accounting for model uncertainty is presented. Implementing this is straightforward using the simple and accurate BIC

A Bayesian Framework for the Analysis of Microarray Expression Data: Regularized t-Test and Statistical Inferences of Gene Changes

by Pierre Baldi, Anthony D. Long - Bioinformatics , 2001
"... Motivation: DNA microarrays are now capable of providing genome-wide patterns of gene expression across many different conditions. The first level of analysis of these patterns requires determining whether observed differences in expression are significant or not. Current methods are unsatisfactory ..."
Abstract - Cited by 491 (6 self) - Add to MetaCart
due to the lack of a systematic framework that can accommodate noise, variability, and low replication often typical of microarray data. Results: We develop a Bayesian probabilistic framework for microarray data analysis. At the simplest level, we model log-expression values by independent normal

A new approach to the maximum flow problem

by Andrew V. Goldberg, Robert E. Tarjan - JOURNAL OF THE ACM , 1988
"... All previously known efficient maximum-flow algorithms work by finding augmenting paths, either one path at a time (as in the original Ford and Fulkerson algorithm) or all shortest-length augmenting paths at once (using the layered network approach of Dinic). An alternative method based on the pre ..."
Abstract - Cited by 672 (33 self) - Add to MetaCart
All previously known efficient maximum-flow algorithms work by finding augmenting paths, either one path at a time (as in the original Ford and Fulkerson algorithm) or all shortest-length augmenting paths at once (using the layered network approach of Dinic). An alternative method based

Reducing Multiclass to Binary: A Unifying Approach for Margin Classifiers

by Erin L. Allwein, Robert E. Schapire, Yoram Singer - JOURNAL OF MACHINE LEARNING RESEARCH , 2000
"... We present a unifying framework for studying the solution of multiclass categorization problems by reducing them to multiple binary problems that are then solved using a margin-based binary learning algorithm. The proposed framework unifies some of the most popular approaches in which each class ..."
Abstract - Cited by 561 (20 self) - Add to MetaCart
We present a unifying framework for studying the solution of multiclass categorization problems by reducing them to multiple binary problems that are then solved using a margin-based binary learning algorithm. The proposed framework unifies some of the most popular approaches in which each class

The emotional dog and its rational tail: a social intuitionist approach to moral judgment

by Jonathan Haidt - Psychological Review , 2001
"... This is the manuscript that was published, with only minor copy-editing alterations, as: Haidt, J. (2001). The emotional dog and its rational tail: A social intuitionist approach to moral judgment. Psychological Review. 108, 814-834 Copyright 2001, American Psychological Association To obtain a repr ..."
Abstract - Cited by 691 (21 self) - Add to MetaCart
This is the manuscript that was published, with only minor copy-editing alterations, as: Haidt, J. (2001). The emotional dog and its rational tail: A social intuitionist approach to moral judgment. Psychological Review. 108, 814-834 Copyright 2001, American Psychological Association To obtain a

Variational algorithms for approximate Bayesian inference

by Matthew J. Beal , 2003
"... The Bayesian framework for machine learning allows for the incorporation of prior knowledge in a coherent way, avoids overfitting problems, and provides a principled basis for selecting between alternative models. Unfortunately the computations required are usually intractable. This thesis presents ..."
Abstract - Cited by 440 (9 self) - Add to MetaCart
The Bayesian framework for machine learning allows for the incorporation of prior knowledge in a coherent way, avoids overfitting problems, and provides a principled basis for selecting between alternative models. Unfortunately the computations required are usually intractable. This thesis presents

Probabilistic Inference Using Markov Chain Monte Carlo Methods

by Radford M. Neal , 1993
"... Probabilistic inference is an attractive approach to uncertain reasoning and empirical learning in artificial intelligence. Computational difficulties arise, however, because probabilistic models with the necessary realism and flexibility lead to complex distributions over high-dimensional spaces. R ..."
Abstract - Cited by 736 (24 self) - Add to MetaCart
Probabilistic inference is an attractive approach to uncertain reasoning and empirical learning in artificial intelligence. Computational difficulties arise, however, because probabilistic models with the necessary realism and flexibility lead to complex distributions over high-dimensional spaces

Verb Semantics And Lexical Selection

by Zhibiao Wu , 1994
"... ... structure. As Levin has addressed (Levin 1985), the decomposition of verbs is proposed for the purposes of accounting for systematic semantic-syntactic correspondences. This results in a series of problems for MT systems: inflexible verb sense definitions; difficulty in handling metaphor and new ..."
Abstract - Cited by 551 (4 self) - Add to MetaCart
and new usages; imprecise lexical selection and insufficient system coverage. It seems one approach is to apply probability methods and statistical models for some of these problems. However, the question reminds: has PSR exhausted the potential of the knowledge-based approach? If not, are there any

Smooth minimization of nonsmooth functions

by Yu. Nesterov - Math. Programming , 2005
"... In this paper we propose a new approach for constructing efficient schemes for nonsmooth convex optimization. It is based on a special smoothing technique, which can be applied to the functions with explicit max-structure. Our approach can be considered as an alternative to black-box minimization. F ..."
Abstract - Cited by 523 (1 self) - Add to MetaCart
In this paper we propose a new approach for constructing efficient schemes for nonsmooth convex optimization. It is based on a special smoothing technique, which can be applied to the functions with explicit max-structure. Our approach can be considered as an alternative to black-box minimization
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