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The Large-Scale Organization of Metabolic Networks

by H. Jeong, B. Tombor, R. Albert, Z. N. Oltvai, A.-L. Barabási , 2000
"... In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular ..."
Abstract - Cited by 609 (7 self) - Add to MetaCart
functions, their large-scale structure is essentially unknown. Here we present the first systematic comparative mathematical analysis of the metabolic networks of 43 organisms representing all three domains of life. We show that, despite significant variances in their individual constituents and pathways

Imagenet: A large-scale hierarchical image database

by Jia Deng, Wei Dong, Richard Socher, Li-jia Li, Kai Li, Li Fei-fei - In CVPR , 2009
"... The explosion of image data on the Internet has the potential to foster more sophisticated and robust models and algorithms to index, retrieve, organize and interact with images and multimedia data. But exactly how such data can be harnessed and organized remains a critical problem. We introduce her ..."
Abstract - Cited by 840 (28 self) - Add to MetaCart
datasets. Constructing such a large-scale database is a challenging task. We describe the data collection scheme with Amazon Mechanical Turk. Lastly, we illustrate the usefulness of ImageNet through three simple applications in object recognition, image classification and automatic object clustering. We

The anatomy of a large-scale hypertextual web search engine.

by Sergey Brin , Lawrence Page - Comput. Netw. ISDN Syst., , 1998
"... Abstract In this paper, we present Google, a prototype of a large-scale search engine which makes heavy use of the structure present in hypertext. Google is designed to crawl and index the Web efficiently and produce much more satisfying search results than existing systems. The prototype with a fu ..."
Abstract - Cited by 4673 (5 self) - Add to MetaCart
Abstract In this paper, we present Google, a prototype of a large-scale search engine which makes heavy use of the structure present in hypertext. Google is designed to crawl and index the Web efficiently and produce much more satisfying search results than existing systems. The prototype with a

Automatically characterizing large scale program behavior

by Timothy Sherwood, Erez Perelman, Greg Hamerly , 2002
"... Understanding program behavior is at the foundation of computer architecture and program optimization. Many pro-grams have wildly different behavior on even the very largest of scales (over the complete execution of the program). This realization has ramifications for many architectural and com-pile ..."
Abstract - Cited by 778 (41 self) - Add to MetaCart
-ior of an arbitrary section of execution in a program. To this end we examine the use of Basic Block Vectors. We quantify the effectiveness of Basic Block Vectors in capturing program behavior across several different architectural met-rics, explore the large scale behavior of several programs, and develop a set

A Security Architecture for Computational Grids

by Ian Foster , Carl Kesselman, Gene Tsudik, Steven Tuecke , 1998
"... State-of-the-art and emerging scientific applications require fast access to large quantities of data and commensurately fast computational resources. Both resources and data are often distributed in a wide-area network with components administered locally and independently. Computations may involve ..."
Abstract - Cited by 568 (47 self) - Add to MetaCart
involve hundreds of processes that must be able to acquire resources dynamically and communicate e#ciently. This paper analyzes the unique security requirements of large-scale distributed (grid) computing and develops a security policy and a corresponding security architecture. An implementation

Architectural Styles and the Design of Network-based Software Architectures

by Roy Thomas Fielding , 2000
"... The World Wide Web has succeeded in large part because its software architecture has been designed to meet the needs of an Internet-scale distributed hypermedia system. The Web has been iteratively developed over the past ten years through a series of modifications to the standards that define its ..."
Abstract - Cited by 1119 (1 self) - Add to MetaCart
The World Wide Web has succeeded in large part because its software architecture has been designed to meet the needs of an Internet-scale distributed hypermedia system. The Web has been iteratively developed over the past ten years through a series of modifications to the standards that define its

The cascade-correlation learning architecture

by Scott E. Fahlman, Christian Lebiere - Advances in Neural Information Processing Systems 2 , 1990
"... Cascade-Correlation is a new architecture and supervised learning algorithm for artificial neural networks. Instead of just adjusting the weights in a network of fixed topology, Cascade-Correlation begins with a minimal network, then automatically trains and adds new hidden units one by one, creatin ..."
Abstract - Cited by 801 (6 self) - Add to MetaCart
-Correlation architecture has several advantages over existing algorithms: it learns very quickly, the network determines its own size and topology, it retains the structures it has built even if the training set changes, and it requires no back-propagation of error signals through the connections of the network.

The PARSEC benchmark suite: Characterization and architectural implications

by Christian Bienia, Sanjeev Kumar, Jaswinder Pal Singh, Kai Li - IN PRINCETON UNIVERSITY , 2008
"... This paper presents and characterizes the Princeton Application Repository for Shared-Memory Computers (PARSEC), a benchmark suite for studies of Chip-Multiprocessors (CMPs). Previous available benchmarks for multiprocessors have focused on high-performance computing applications and used a limited ..."
Abstract - Cited by 518 (4 self) - Add to MetaCart
number of synchronization methods. PARSEC includes emerging applications in recognition, mining and synthesis (RMS) as well as systems applications which mimic large-scale multithreaded commercial programs. Our characterization shows that the benchmark suite covers a wide spectrum of working sets

Cognitive architecture and instructional design

by John Sweller, Jeroen J. G. Van Merrienboer, Fred G. W. C. Paas - Educational Psychology Review , 1998
"... Cognitive load theory has been designed to provide guidelines intended to assist in the presentation of information in a manner that encourages learner activities that optimize intellectual performance. The theory assumes a limited capacity working memory that includes partially independent subcompo ..."
Abstract - Cited by 503 (53 self) - Add to MetaCart
subcomponents to deal with auditory/verbal material and visual/2- or 3-dimensional information as well as an effectively unlimited long-term memory, holding schemas that vary in their degree of automation. These structures and functions of human cognitive architecture have been used to design a variety of novel

Principled design of the modern web architecture

by Roy T. Fielding, Richard N. Taylor - ACM Trans. Internet Techn
"... The World Wide Web has succeeded in large part because its software architecture has been designed to meet the needs of an Internet-scale distributed hypermedia system. The modern Web architecture emphasizes scalability of component interactions, generality of interfaces, independent deployment of c ..."
Abstract - Cited by 531 (14 self) - Add to MetaCart
The World Wide Web has succeeded in large part because its software architecture has been designed to meet the needs of an Internet-scale distributed hypermedia system. The modern Web architecture emphasizes scalability of component interactions, generality of interfaces, independent deployment
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