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CA: Yeast genes controlling responses to topogenic signals in a model transmembrane protein

by Carol A. Harley, Carol A Harley - Mol Biol Cell
"... Yeast genes controlling responses to topogenic signals in a model transmembrane protein ..."
Abstract - Cited by 7 (0 self) - Add to MetaCart
Yeast genes controlling responses to topogenic signals in a model transmembrane protein

Early Expression of Yeast Genes Affected by Chemical Stress†

by C. Jacq , 2004
"... The variety of environmental stresses is probably the major challenge imposed on transcription activators and the transcriptional machinery. To precisely describe the very early genomic response developed by yeast to accommodate a chemical stress, we performed time course analyses of the modificatio ..."
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of the modifications of the yeast gene expression program which immediately follows the addition of the antimitotic drug benomyl. Similar analyses were conducted with different isogenic yeast strains in which genes coding for relevant transcription factors were deleted and coupled with efficient bioinformatics tools

Systematic Management and Analysis of Yeast Gene Expression Data

by John Aach, Wayne Rindone, George M. Church , 2000
"... roarrays, Serial Analysis of Gene Expression (SAGE), and other techniques (Velculescu et al. 1995; Lockhart et al. 1996; DeRisi et al. 1997), has led to the rapid accumulation of large expression data sets and the development of the field of functional genomics. Functional genomics has been contrast ..."
Abstract - Cited by 39 (4 self) - Add to MetaCart
roarrays, Serial Analysis of Gene Expression (SAGE), and other techniques (Velculescu et al. 1995; Lockhart et al. 1996; DeRisi et al. 1997), has led to the rapid accumulation of large expression data sets and the development of the field of functional genomics. Functional genomics has been

Discovering Statistically Significant Biclusters in Gene Expression Data

by Amos Tanay, Roded Sharan, Ron Shamir - In Proceedings of ISMB 2002 , 2002
"... In gene expression data, a bicluster is a subset of the genes exhibiting consistent patterns over a subset of the conditions. We propose a new method to detect significant biclusters in large expression datasets. Our approach is graph theoretic coupled with statistical modelling of the data. Under p ..."
Abstract - Cited by 302 (4 self) - Add to MetaCart
plausible assumptions, our algorithm is polynomial and is guaranteed to find the most significant biclusters. We tested our method on a collection of yeast expression profiles and on a human cancer dataset. Cross validation results show high specificity in assigning function to genes based

Super-paramagnetic clustering of yeast gene expression profiles

by G. Getz , E. Levine , E. Domany , M. Q. Zhang , 1999
"... ..."
Abstract - Cited by 16 (5 self) - Add to MetaCart
Abstract not found

Exploring the Conditional Coregulation of Yeast Gene Expression Through Fuzzy K-Means Clustering

by A P Gasch, M P Eisen , 2002
"... Background: Organisms simplify the orchestration of gene expression by coregulating genes whose products function together in the cell. Many proteins serve different roles depending on the demands of the organism, and therefore the corresponding genes are often coexpressed with different groups o ..."
Abstract - Cited by 137 (0 self) - Add to MetaCart
Background: Organisms simplify the orchestration of gene expression by coregulating genes whose products function together in the cell. Many proteins serve different roles depending on the demands of the organism, and therefore the corresponding genes are often coexpressed with different groups

P-tree Classification of Yeast Gene Deletion Data

by Amal Perera, Anne Denton, Pratap Kotala, William Jockheck, Willy Valdivia Granda, William Perrizo , 2002
"... Genomics data has many properties that make it different from "typical" relational data. The presence of multi-valued attributes as well as the large number of null values led us to a P-tree-based bit-vector representation in which matching 1-values were counted to evaluate similarity betw ..."
Abstract - Cited by 10 (4 self) - Add to MetaCart
between genes. Quantitative information such as the number of interactions was also included in the classifier. Interaction information allowed us to extend the known properties of one protein with information on its interacting neighbors. Different feature attributes were weighted independently

The fission yeast genes pypl + and pyp2 + encode protein tyrosine phosphatases that negatively regulate mitosis

by S Ottilie, J Chernoff, G Hannig, C S Hoffman, R L Erikson, Sabine Ottilie, Jonathan Chernoff, T Gerhard Hannig, Charles S. Hoffman, R. L. Erikson , 1992
"... The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis. ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis.

Semi-Supervised Clustering of Yeast Gene Expression Data

by A. Schönhuth, I. G. Costa, A. Schliep , 2006
"... To identify modules of interacting molecules often gene expression is analyzed with clustering methods. Constrained or semi-supervised clustering provides a framework to augment the primary, gene expression data with secondary data, to arrive at biological meaningful clusters. Here, we present an a ..."
Abstract - Cited by 2 (1 self) - Add to MetaCart
an approach using constrained clustering and present favorable results on a biological data set of gene expression time-courses in Yeast together with predicted transcription factor binding site information.

Factors affecting splicing strength of yeast genes,”Comparative

by Pinchao Ma , Xuhua Xia - and Functional Genomics
"... Accurate and efficient splicing is of crucial importance for highly-transcribed intron-containing genes (ICGs) in rapidly replicating unicellular eukaryotes such as the budding yeast Saccharomyces cerevisiae. We characterize the 5 and 3 splice sites (ss) by position weight matrix scores (PWMSs), wh ..."
Abstract - Cited by 3 (2 self) - Add to MetaCart
Accurate and efficient splicing is of crucial importance for highly-transcribed intron-containing genes (ICGs) in rapidly replicating unicellular eukaryotes such as the budding yeast Saccharomyces cerevisiae. We characterize the 5 and 3 splice sites (ss) by position weight matrix scores (PWMSs
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