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23,027
Phylogenetic identification and in situ detection of individual microbial cells without cultivation
- MICROBIOL. REV.
, 1995
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The embryonic cell lineage of the nematode Caenorhabditis elegans
- Dev. Biol
, 1983
"... The number of nongonadal nuclei in the free-living soil nematode Caenorhabditis elegans increases from about 550 in the newly hatched larva to about 810 in the mature hermaphrodite and to about 970 in the mature male. The pattern of cell divisions which leads to this increase is essentially invarian ..."
Abstract
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Cited by 540 (19 self)
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invariant among individuals; rigidly determined cell lineages generate a fixed number of progeny cells of strictly specified fates. These lineages range in length from one to eight sequential divisions and lead to significant developmental changes in the neuronal, muscular, hypodermal, and digestive systems
The Large-Scale Organization of Metabolic Networks
, 2000
"... In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular ..."
Abstract
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Cited by 609 (7 self)
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In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular
Neuronal Synchrony: A Versatile Code for the Definition of Relations?
, 1999
"... temporal relations requires the joint evaluation of responses from more than one neuron, only experiments that permit simultaneous measurements of responses 60528 Frankfurt from multiple units are considered. These include multi-Federal Republic of Germany electrode recordings from multiple individu ..."
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Cited by 470 (20 self)
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individual cells, but also measurements of local field potentials (LFPs) and electroencephalographic (EEG) or magnetoencephalo-Most of our knowledge about the functional organization of neuronal systems is based on the analysis of the firing patterns of individual neurons that have been recorded one by one
Alternative isoform regulation in human tissue transcriptomes
- Nature
, 2008
"... Through alternative processing of pre-mRNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an in-depth analysis of 15 diverse human tissue and cell line transcriptomes based on deep sequencing of ..."
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Cited by 545 (6 self)
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Through alternative processing of pre-mRNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an in-depth analysis of 15 diverse human tissue and cell line transcriptomes based on deep sequencing
The Advantages of Evolutionary Computation
, 1997
"... Evolutionary computation is becoming common in the solution of difficult, realworld problems in industry, medicine, and defense. This paper reviews some of the practical advantages to using evolutionary algorithms as compared with classic methods of optimization or artificial intelligence. Specific ..."
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Cited by 541 (6 self)
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and optimization mechanism. Evolved biota demonstrate optimized complex behavior at every level: the cell, the organ, the individual, and the population. The problems that biological species have solved are typified by chaos, chance, temporality, and nonlinear interactivities. These are also characteristics
Phase relationship between hippocampal place units and the EEG theta rhythm. Hippocampus 3:317–330
, 1993
"... Many complex spike cells in the hippocampus of the freely moving rat have as their primary correlate the animal's location in an environment (place cells). In contrast, the hippocampal electroencephalograph theta pattern of rhythmical waves (7- 12 Hz) is better correlated with a class of moveme ..."
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Cited by 344 (4 self)
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; to 3.55 " in different cells. The effect appeared to be due to the fact that individual cells had a higher interburst rate than the theta frequency. The phase was highly correlated with spatial location and less well correlated with temporal aspects of behavior, such as the time after place field
Dynamics of Sparsely Connected Networks of Excitatory and Inhibitory Spiking Neurons
, 1999
"... The dynamics of networks of sparsely connected excitatory and inhibitory integrateand -re neurons is studied analytically. The analysis reveals a very rich repertoire of states, including: Synchronous states in which neurons re regularly; Asynchronous states with stationary global activity and very ..."
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Cited by 306 (16 self)
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irregular individual cell activity; States in which the global activity oscillates but individual cells re irregularly, typically at rates lower than the global oscillation frequency. The network can switch between these states, provided the external frequency, or the balance between excitation
Learning Invariance From Transformation Sequences
, 1991
"... Introduction How can we consistently recognize objects when changes in the viewing angle, eye position, distance, size, orientation, relative position, or deformations of the object itself (e.g., of a newspaper or a gymnast) can change their retinal projections so significantly? The visual system m ..."
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Cited by 318 (2 self)
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. Electrophysiological experiments suggest that the invariance properties of perception may be due to the receptive field characteristics of individual cells in the visual system. Complex cells in the primary visual cortex exhibit approximate invariance to position within a limited range (Hubel and Wiesel 1962), while
The Variable Discharge of Cortical Neurons: Implications for Connectivity, Computation, and Information Coding
- J. Neurosci
, 1998
"... this paper we propose that the irregular ISI arises as a consequence of a specific problem that cortical neurons must solve: the problem of dynamic range or gain control. Cortical neurons receive 3000--10,000 synaptic contacts, 85% of which are asymmetric and hence presumably excitatory (Peters, 198 ..."
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Cited by 345 (3 self)
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, 1987; Braitenberg and Schuz, 1991). More than half of these contacts are thought to arise from neurons within a 100--200 #m radius of the target cell, reflecting the stereotypical columnar organization of neocortex. Because neurons within a cortical column typically share similar physiological
Results 1 - 10
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23,027