"... In PAGE 2: ... Monozygotic twins have less variation within pairs as compared to dizygotic twins and sibling pairs. Table2 indeed shows that the correlation coefficients for all cytokines are higher for monozygotic twin pairs than for dizygotic twin and sibling pairs. This suggests that heritability plays a role in the LPS-induced cytokine response.... In PAGE 2: ... This suggests that heritability plays a role in the LPS-induced cytokine response. Results from the variance decomposition models con- firmed that for all cytokines, over 50% of the variance is genetically determined ( Table2 ). IL-1ra and TNF-a had the lowest estimate (53%), while IL-1b had the highest estimate (86%).... ..."

"... In PAGE 7: ... The objective is a simple notation that expresses clear distinctions where needed with minimal additions. The notation for activity modeling summarized in Table1 adds to the established notation already used in usage-centered design four new symbols for activities, actions, artifacts, and non-actor participants. It is important to keep in mind that these models are being introduced to maximize utility and efficiency in representing activity context for interaction design purposes rather than for software engineering.... In PAGE 9: ... competing activities involving shared resources in common with proximate activities 4. adjacent activities in the same setting but otherwise unrelated to proximate activities Activities are represented in an Activity Map by the block shape shown in Table1 . A line or arrow connecting one activity to another represents a relationship.... In PAGE 13: ... In this context, actions refer to goal-directed interactions among actors or players and between them and artifacts other than the system of reference. Actions are represented by a distinct symbol (the barred ellipse seen in Table1 ), a variation of the symbol already generally used to represent task cases. The Task Map, a model used to represent the interrelationships among task cases in usage- centered design, can be extended to incorporate activities and actions.... ..."

"... In PAGE 15: ...eactivation (i.e. greater activation in the control task tha n the experimental task) was observed in the medial portions of the medial and superior frontal gyri (BAs 9/10 and 6), posterior cingulate (BAs 23, 29, 30, 31) and cuneus (BA 18) . Insert Table4 about here Discussion. The two conditions studied here differed only in the orientation of the figures presented: in the experimental condition, a mental transformation was required to orient the figures to upright.... ..."