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Abstract: This article will describe some of the physiological and neurochemical mechanisms that might mediate episodic memory consolidation. Firstly, I will review the neuropsychological and computational evidence for a two-stage model of memory consolidation. I will then describe electrophysiological data that support this concept and suggest that the two stages are linked to different stages of the sleep--wake cycle when encoding and consolidation might occur. In the final section, I Neuromodulation: (Update)
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.... for learning rate Acetylcholine is known to modulate the synaptic plasticity in the hippocampus and the cerebral cortex (Hasselmo, 1999). Depletion of acetylcholine leads to memory disorders like Alzheimer s disease. These facts point to the possibility that 5...
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BibTeX entry: (Update)
Hasselmo, M.E. (1999) Neuromodulation: acetylcholine and memory consolidation. Trends in Cognitive Sciences, 3:351-359. http://citeseer.ist.psu.edu/hasselmo99neuromodulation.html More
@misc{ hasselmo99neuromodulation,
author = "M. Hasselmo",
title = "Neuromodulation: acetylcholine and memory consolidation",
text = "Hasselmo, M.E. (1999) Neuromodulation: acetylcholine and memory consolidation.
Trends in Cognitive Sciences, 3:351-359.",
year = "1999",
url = "citeseer.ist.psu.edu/hasselmo99neuromodulation.html" }
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