| Bernardo LS, Prince DA (1982) Cholinergic excitation of mammalian hippocampal pyramidal cells. Brain Res 249:315--331. |
....benefits. Several in vitro experiments have demonstrated that application of ACh, muscarinic agonists, or anticholinesterases increased neuronal excitability [reduced postburst afterhyperpolarization (AHP) and spike frequency adaptation (accommodation) of hippocampal pyramidal neurons (Bernardo and Prince, 1981, 1982; Cole and Nicoll, 1983, 1984a,b; Madison and Nicoll, 1984; Halliwell, 1990; Taylor and Griffith, 1993; Pedarzani and Storm, 1996) Furthermore, both the AHP and accommodation were reduced in CA1 neurons from young and aging rabbits that acquired eyeblink conditioning, but not in trained rabbits ....
....RBC AChE activity was significantly different between the two treatment groups (F (1,5) # 28.79; p # 0. 003) Carbachol increased neuronal excitability Bath application of carbachol significantly increased the excitability of CA1 neurons from both young and aging subjects, as reported previously (Bernardo and Prince, 1982; Cole and Nicoll, 1983, 1984a,b; Potier et al. 1992; Taylor and Griffith, 1993; Pedarzani and Storm, 1996) At 500 nM, the AHP amplitude was reduced by #1.0 mV in CA1 neurons from both young (1.18 # 0.30 mV; p # 0.003) and aging (1.17 # 0.27 mV; p # 0.001) subjects (Fig. 6, Table 3) The ....
Bernardo LS, Prince DA (1982) Cholinergic excitation of mammalian hippocampal pyramidal cells. Brain Res 249:315--331.
No context found.
Benardo, L.S. and Prince, D.A. (1982) Cholinergic excitation of mammalian hippocampal pyramidal cells Brain Res. 249, 315--331
No context found.
L. S. Bernardo and D. A. Prince. Cholinergic excitation of mammalian hippocampal pyramidal cells. Brain Research, 249:315--331, 1982a.
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