| L.J. Leon and F.A. Roberge. Directional characteristics of action potential propagation in cardiac muscle. A model study. Circulation Research, 69:378--395, 1991. |
....per time step would be enormous. Hence it is obvious that the problem, as posed for a 1 mm cube, is large enough to overwhelm most desktop computers. As a result, models based on microscopic scale membrane kinetics have been limited to propagation in 2 D sheets or small 3 D blocks of tissue [4, 9, 8]. Bidomain models, represent heart tissue as two continuous, intertwined spaces, the extracellular and the intracellular, separated from each other all throughout by a thin membrane. The electrical properties of this membrane are modeled using the membrane models mentioned above. Due to the ....
L.J. Leon and F.A. Roberge. Directional characteristics of action potential propagation in cardiac muscle. A model study. Circulation Research, 69:378--395, 1991.
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