David L. Glanzman, Eric R. Kandel, and Samuel Schacher. Target-dependent structural changes accompanying long-term synaptic facilitation in aplysia sensory neurons. Science, 249, 1990. Home/Search Document Not in Database Summary Related Articles |
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The Role of Chemical Mechanisms in Neural Computation and Learning - Hiller (Correct)
....affect the degree to which the animal s long term response changes. These phenomena are defined in Section 3.1.1. Mechanisms for long term learning have not yet been extensively explored, though it appears to involve both the production of new proteins [12, 65] and new synapse formation [17]. One apparent mechanism for DNA transcription in long term sensitization is cAMP dependent phosphorylation of a substrate protein that acts as a DNA transcription factor [12] This protein, when activated by cAMP, binds to a particular DNA sequence and activates (or, conversely, inhibits) ....
David L. Glanzman, Eric R. Kandel, and Samuel Schacher. Target-dependent structural changes accompanying long-term synaptic facilitation in aplysia sensory neurons. Science, 249, 1990.
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