| J. G. Defares, J. J. Osborne, and H. H. Hiroshi. Theoretical synthesis of the cardiovascular system. Acta Physiol. Pharm. Neerl., 12:189--265, 1963. 117 |
....combined two ventricles with a pulmonary circuit branch to simulate the effects of Starling heartlung relationship. This work was considered as the starting point for integrative physiology [7] Then in early 1960 s, a six node electrical circuit model was proposed by Defares and his colleagues [8]. In that model, each node consists of a capacitor to ground and is connected to two adjacent nodes by impedances. The varied left and right ventricular capacitances were used to simulate the time varying elastance property of contraction. Early in 1970 s, Dr. Arthur Guyton developed refined com36 ....
J. G. Defares, J. J. Osborne, and H. H. Hiroshi. Theoretical synthesis of the cardiovascular system. Acta Physiol. Pharm. Neerl., 12:189--265, 1963. 117
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