| Y. Cao, A. Janke, P. J. Waddell, M. Westerman, O. Takenaka, S. Murata, N. Okada, S. Paabo, M. Hasegawa, Con ict among individual mitochondrial proteins in resolving the phylogeny of Eutherian orders, J. Mol. Evol., 47(1998), 307-322. |
....in the loss of their shared information. Our theoretical approach is used experimentally to create a fully automated and reasonably accurate software tool based on such a distance to compare two genomes. We demonstrate that a whole mitochondrial genome phylogeny of the Eutherians which con rms [8], can be reconstructed automatically from unaligned complete mitochondrial genomes by use of our software implementing (an approximation of) our theory. These experimental con rmations of the e acity of our comprehensive approach contrasts with recent more specialized approaches such as [37] that ....
....groups of placental mammals are more closely related: Primates, Ferungulates, and Rodents. This is because the maximum likelihood method gives (Ferungulates, Primates, Rodents) grouping for half of the proteins in mitochondial genome, and (Rodents, Ferungulates, Primates) for the other half [8]. In [8] Cao et al. aligned 12 concatenated mitochondrial proteins taken from the following species: rat (Rattus norvegicus) house mouse (Mus musculus) grey seal (Halichoerus grypus) harbor seal (Phoca vitulina) cat (Felis catus) white rhino (Ceratotherium simum) horse (Equus caballus) ....
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Y. Cao, A. Janke, P. J. Waddell, M. Westerman, O. Takenaka, S. Murata, N. Okada, S. Paabo, M. Hasegawa, Con ict among individual mitochondrial proteins in resolving the phylogeny of Eutherian orders, J. Mol. Evol., 47(1998), 307-322.
....main groups of placental mammals are more closely related: Primates, Ferungulates, and Rodents. This is because by the maximum likelihood method, some proteins support the (Ferungulates, Primates, Rodents) grouping while other proteins support the (Rodents, Ferungulates, Primates) grouping (Cao et al. 1998). Cao et al. aligned 12 concatenated mitochondrial proteins from the following species: rat (Rattus norvegicus) house mouse (Mus musculus) grey seal (Halichoerus grypus) harbor seal (Phoca vitulina) cat (Felis catus) white rhino (Ceratotherium simum) horse (Equus caballus) nback whale ....
....from mtDNAs of the above species, and performed the same computation. We have obtained the same tree. Phylogenetic Position of the Rodents We also analyzed a larger dataset derived from the 34 taxa mitochondrial genome phylogeny in (Reyes et al. 2000) This dataset included 19 of the 20 taxa in (Cao et al. 1998) and the additional 15 taxa: aardvark (Orycteropus afer) armadillo (Dasy pus novemcintus) baboon (Papio hamadryas) dog (Canis familiaris) donkey (Equus asinus) dormouse (Glis glis) elephant (Loxodonta africana) fruit bat (Artibeus jamaicensis) great rhino (Rhinoceros unicornis) guinea ....
[Article contains additional citation context not shown here]
Cao, Y., Janke, A., Waddell, P. J., Westerman, M., Takenaka, O., Murata, S., Okada, N., Paabo, S., and Hasegawa, M. (1998). Con ict among individual mitochondrial proteins in resolving the phylogeny of eutherian orders. J. Mol. Evol., 47:307-322.
....Figure 1.1 is called a species tree. Due to various CHAPTER 1. INTRODUCTION 4 biological reasons, a gene tree in general does not accurately re ect the evolutionary history at the species level (one obvious reason being that the trees obtained from di erent genes are not necessarily consistent. [10]. As more genomes are sequenced, methods that utilize the entire genome are in active research (for example, see [41, 63, 49, 36] Clearly, the inference of phylogenetic trees is not exclusively biological, but also involves mathematical modeling and algorithm design. For example, given two ....
....but not necessarily the species themselves. It is often the case that di erent genes lead to di erent trees. However, if the biologist would like to have a species tree, it is unlikely that trees inferred based on di erent genes would agree with each other. For instance, in a recent biology paper [10] Cao et. al studied the phylogenetic relationship among primates (e.g. human ) ferungulates (e.g. horse) and rodents (e.g. mouse) using the genes on the H strand of mitochondria DNA and found that two di erent trees were constructed depending on the gene used in the analysis. Di erent ....
Cao, Y. and Janke, A. and Waddell, P. and Westerman, M. and Takenake, O. and Murata, S. and Okada, N. and Paabo, S. and Hasegawa, M. 1998. Con ict among individual mitochondrial proteins in resolving the phylogeny of eutherian orders Molecular Evolution 47:307-322.
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