J.S. Kahle, C.W. Cotman, Carbachol depresses the synaptic responses in the medial but not the lateral perforant path, Brain Res. 482 (1989) 159 -- 163. Home/Search Document Not in Database Summary Related Articles Check |
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Free Recall and Recognition in a Network Model of the.. - Hasselmo, Wyble (1997) (Correct)
....Cholinergic agonists have been shown to strongly suppress excitatory synaptic transmission at specific connections within the hippocampal formation. For example, acetylcholine and cholinergic agonists suppress synaptic potentials elicited in the middle molecular layer of the dentate gyrus [51,52], in stratum radiatum of region CA3 [53,54] and in stratum radiatum of region CA1 [53,55 57] These effects appear to be selective to specific synapses, since cholinergic agonists have much weaker effects on synaptic transmission in stratum lacunosum moleculare of CA1 [57] and in the outer ....
....the neurons spike in a more sustained manner [61,63] Scopolamine blocks this effect, resulting in less spiking activity. 4) Acetylcholine enhances the rate of synaptic modification in the cortex [65,67] Scopolamine blocks this effect, resulting in less change in the strength of synapses. [52]. Blockade of this selective suppression by scopolamine may enhance proactive interference from previously stored patterns during the learning of new input patterns [47,54,57,58] 1.3.2. Scopolamine blocks the cholinergic depolarization of hippocampal neurons Cholinergic agonists have been shown ....
J.S. Kahle, C.W. Cotman, Carbachol depresses the synaptic responses in the medial but not the lateral perforant path, Brain Res. 482 (1989) 159 -- 163.
Neuromodulation: Acetylcholine and memory consolidation - Hasselmo (1999) (3 citations) (Correct)
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Kahle, J.S. and Cotman, C.W. (1989) Carbachol depresses synaptic responses in the medial but not the lateral perforant path Brain Res.
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