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Koonin, E. V. (1999) The emerging paradigm and open problems in comparative genomics. Bioinformatics, 15 (4), 265-- 266. Editorial.

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Similarity Distance and Phylogeny - Li, Li, Ma, Vitányi (2002)   (Correct)

.... source code in assignments The fast advance of worldwide genome sequencing projects has raised the following fundamental question to prominence in contemporary biological science: how do we compare two genomes This problem gured on two recent lists of major open problems in bioinformatics [20, 38]. Our aim here is not to de ne a similarity measure for each application eld; we develop a general mathematical theory of similarity. To obtain evidence that the theory signi cantly addresses the question (and is not only theoretically satisfactory) we test it on real world applications in a ....

E.V. Koonin, The emerging paradigm and open problems in comparative genomics, Bioinformatics, 15(1999), 265-266.


Algorithmic Complexity - Li, Vitányi   (Correct)

....also used in a more serious manner to build correct phylogenies from complete mitochondrial genomes of mammals and confirmed a biological conjecture [1] that ferungulates 4 are closer to primates than to rodents. It is a major challenge in bioinformatics to find good methods to compare genomes [10, 19]. Traditional approaches of computing the phylogeny require multiple alignment. They would not work here since chain letters contain swapped sentences and genomes contain translocated genes and noncoding regions. Inductive Reasoning: Solomonoff [16] argues that all inference problems can be cast ....

Koonin, E.V., The emerging paradigm and open problems in comparative genomics. Bioinformatics 15, 265--266 (1999).


Simultaneous Identification of Conserved Regions and Inversions.. - Lago   (Correct)

No context found.

Koonin, E. V. (1999) The emerging paradigm and open problems in comparative genomics. Bioinformatics, 15 (4), 265-- 266. Editorial.


The Similarity Metric - Xin (2003)   (8 citations)  (Correct)

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E.V. Koonin, The emerging paradigm and open problems in comparative genomics, Bioinformatics, 15(1999), 265-266.


The Similarity Metric - Li, Chen, Li, Ma, Vitanyi (2003)   (8 citations)  (Correct)

No context found.

E.V. Koonin, The emerging paradigm and open problems in comparative genomics, Bioinformatics, 15(1999), 265-266.


The k-Feature Set Problem is W [2]-complete - Cotta, Moscato (2003)   (Correct)

No context found.

E.V. Koonin. The emerging paradigm and open problems in comparative genomics. Bioinformatics, 15:265--266, 1999.


Applying Memetic Algorithms to the Analysis of.. - Cotta, Mendes.. (2003)   (Correct)

No context found.

E.V. Koonin. The emerging paradigm and open problems in comparative genomics. Bioinformatics, 15:265--266, 1999.


Simultaneous Identification of Conserved Regions and Inversions.. - Lago   (Correct)

No context found.

Koonin, E. V. (1999) The emerging paradigm and open problems in comparative genomics. Bioinformatics, 15 (4), 265-- 266. Editorial.


An Information Based Sequence Distance and Its.. - Li, Badger, Chen, .. (2001)   (9 citations)  (Correct)

No context found.

Algorithmica, 13:180-210. Koonin, E. V. (1999). The emerging paradigm and open problems in comparative genomics. Bioinformatics, 15:265-266.

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