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Biomarker Discovery in Microarray Gene Expression Data with Gaussian...



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Abstract: Motivation: In clinical practice, pathological phenotypes are often labelled with ordinal scales rather than binary, e.g. the Gleason grading system for tumor cell differentiation. However, in the literature of microarray analysis, these ordinal labels have been rarely treated in a principled way. This paper describes a gene selection algorithm based on Gaussian processes to discover consistent gene expression patterns associated with ordinal clinical phenotypes. The technique of automatic... (Update)

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@misc{ in-bioinformatics,
  author = "Biomarker Discovery In",
  title = "Bioinformatics",
  url = "citeseer.ist.psu.edu/734748.html" }
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