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by M. Sermesant, Y. Coudire, H. Delingette, N. Ayache, J. Sainte-marie, D. Chapelle, F. Clment, M. Sorine
ftp://ftp-sop.inria.fr/epidaure/Publications/Sermesant/ms4cmsICEMA.ps.gz
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Abstract:
We present recent advances on a 3D numerical modeling of the myocardium which couples electrical and biomechanical models. The long-term objective is to simulate a realistic contraction of the heart from both electrical measurements (typically the ECG) and geometrical measurements (typically provided by medical imaging). This realistic contraction should provide useful quantitative parameters for the diagnosis and also for guiding some new forms of therapy. Our modeling is based on a multi-scale analysis ranging from microscopic to macroscopic scales, and integrates a priori information on the overall geometry and on the ber directions extracted from specic medical imaging techniques (e.g. MRI). The FitzHugh-Nagumo equations are solved along with a constitutive law based on the Hill-Maxwell Rheological model, on which a data assimilation analysis is done. In medical image analysis, we believe that this new generation of physics-based deformable models will be useful to provide a more robust quantitative interpretation of temporal series of cardiac images. 1
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