Monitoring gene expression profiles is a novel approach in cancer diagnosis. Several studies showed that prediction of cancer types using gene expression data is promising and very informative. The Support Vector Machine (SVM) is one of the classification methods successfully applied to the cancer diagnosis problems using gene expression data. However, its optimal extension to more than two classes was not obvious, which might impose limitations in its application to multiple tumor types. In this paper, we analyze a couple of published multiple cancer types data sets by the multicategory SVM, which is a recently proposed extension of the binary SVM. 1
|
4514
|
Statistical Learning Theory
– Vapnik
- 1998
|
|
1103
|
A Tutorial on Support Vector Machines for Pattern Recognition
– Burges
- 1998
|
|
727
|
Spline Models for Observational Data
– Wahba
- 1990
|
|
688
|
A training algorithm for optimal margin classifiers
– Boser, Guyon, et al.
- 1992
|
|
573
|
A Probabilistic Theory of Pattern Recognition
– Devroye, Gyorfi, et al.
- 1996
|
|
511
|
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
– Goloub, Slonim, et al.
- 1999
|
|
495
|
Training of Support Vector Machine using Sequential Minimal Optimization
– Platt
- 1999
|
|
191
|
Comparison of discrimination methods for the classification of tumors using gene expression data
– Dudoit, Fridlyand, et al.
- 2002
|
|
172
|
A comparison of methods for multi-class support vector machines
– Hsu, Lin
- 2001
|
|
171
|
An improved training algorithm for support vector machines
– Osuna, Freund, et al.
|
|
162
|
Support vector machine classification and validation of cancer tissue samples using microarray expression data
– Furey, Cristianini, et al.
- 2000
|
|
129
|
Sequenital minimal optimization: A fast algorithm for training support vector machines
– Platt
- 1998
|
|
127
|
Multi-Class Support Vector Machines
– Weston, Watkins
- 1998
|
|
124
|
Some results on Tchebycheffian spline functions
– Kimeldorf, Wahba
- 1971
|
|
113
|
Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks
– Khan, Wei, et al.
- 2001
|
|
105
|
Support Vector Machine, Reproducing Kernel Hilbert Spaces and Randomized GACV
– Wahba
|
|
77
|
Another approach to polychotomous classification
– Friedman
- 1996
|
|
71
|
On the Learnability and Design of Output Codes for Multiclass problems
– Crammer, Singer
- 2000
|
|
56
|
Support vector machines for multi-class pattern recognition
– Weston, Watkins
- 1999
|
|
52
|
Asymptotic analysis of penalized likelihood and related estimates
– Cox, O’Sullivan
- 1990
|
|
46
|
A unified framework for regularization networks and support vector machines
– Evgenious, Pontil, et al.
- 1999
|
|
45
|
Successive overrelaxation for support vector machines
– MANGASARIAN, MUSICANT
- 1999
|
|
42
|
Support vector machines for classification in nonstandard situations
– Lin, Lee, et al.
|
|
39
|
Support vector machines and the Bayes rule in classification
– Lin
|
|
39
|
On the estimation of a probability density function by the maximum penalized likelihood method
– Silverman
- 1982
|
|
37
|
Tsybakov, “Smooth discrimination analysis
– Mammen, B
- 1999
|
|
28
|
Some results on Tchebychean spline functions
– Kimeldorf, Wahba
- 1971
|
|
26
|
Robust bounds on generalization from the margin distribution
– Shawe-Taylor, Cristianini
- 1998
|
|
17
|
SSVM: A smooth support vector machine for classification
– Lee, Mangasarian
|
|
16
|
GACV for support vector machines, or , another way to look at margin-like quantities
– Wahba, Lin, et al.
- 1999
|
|
16
|
Optimal rates of convergence to Bayes risk in nonparametric discrimination
– Marron
- 1983
|
|
11
|
Tensor product space ANOVA models
– Lin
- 2000
|
|
5
|
Multiclass Classification of SRBCTs
– Yeo, Poggio
- 2001
|
|
4
|
Empirical processes in M-estimation. Cambridge university press
– Geer
- 1999
|
|
3
|
Gacv for Support Vector
– Wahba, Lin, et al.
- 2000
|
|
1
|
The role of E-proteins
– Bain, Murre
- 1998
|
|
1
|
Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors, Eur J Biochem 234: 406--413
– Charrasse, Mazel, et al.
- 1995
|
|
1
|
Comparison of cell surface antigen HBA71 (p30/32MIC2), neuron-specific enolase, and vimentin in the immunohistochemical analysis of Ewing's sarcoma of bone., Am J Surg Pathol 16: 746--755
– Fellinger, Garin-Chesa, et al.
- 1992
|
|
1
|
Hem-1, a potential membrane protein, with expression restricted to blood cells, Biochim Biophys Acta 1090: 241
– Hromas, Collins, et al.
- 1991
|
|
1
|
Immunocytochemical study of 12E7 in small round-cell tumours of childhood: an assessment of its sensitivity and specificity., Histopathology 23: 557--561
– Ramani, Rampling, et al.
- 1993
|
|
1
|
Immunohistochemical profile of monoclonal antibody O13: antibody that recognizes glycoprotein p30/32MIC2 and is useful in diagnosing Ewing's sarcoma and peripheral neuroepithelioma., Am J Surg Pathol 18: 486--494
– Weidner, Tjoe
- 1994
|