IXDB, an Integrated Database for Genomic Data
Abstract:
The generation of physical maps at the chromosomal scale and at a resolution sufficient for large scale sequencing requires more data, experiments and resources than can be produced by a single research group. This is reflected by the fact that most chromosomes are informally split into regions of research interest. These are then often exclusively tackled by a small number of groups, following certain specialized research interests such as the search for a specific gene. In addition, many interesting questions other than those aimed at genome sequencing require an overall overview, such as the determination of chromosome structure conservation across species. Such questions are currently very tiresome and error-prone to approach, as no single-point and comprehensive interface to all the different datasets is available ([1]). We have developed IXDB, a database focused on the human X chromosome, to assist our mapping projects. IXDB has a relational datamodel and covers the field of mapping information, with growing extensions towards genomic sequences and a more detailed gene representation. IXDB is designed as an integrated database, which means that it includes and tightly integrate data from other public database. It aims to ultimately serve as the above described single-point interface to mapping data of the human X chromosome. It currently contains information from many different
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